WO2004011496A3 - Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof - Google Patents

Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof Download PDF

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Publication number
WO2004011496A3
WO2004011496A3 PCT/EP2002/007440 EP0207440W WO2004011496A3 WO 2004011496 A3 WO2004011496 A3 WO 2004011496A3 EP 0207440 W EP0207440 W EP 0207440W WO 2004011496 A3 WO2004011496 A3 WO 2004011496A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotides
cell
novel
peptides
proteins
Prior art date
Application number
PCT/EP2002/007440
Other languages
French (fr)
Other versions
WO2004011496A2 (en
Inventor
Nalan Utku
Original Assignee
Nalan Utku
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nalan Utku filed Critical Nalan Utku
Priority to EP02758310A priority Critical patent/EP1581554A2/en
Priority to AU2002325299A priority patent/AU2002325299A1/en
Priority to PCT/EP2002/007440 priority patent/WO2004011496A2/en
Publication of WO2004011496A2 publication Critical patent/WO2004011496A2/en
Publication of WO2004011496A3 publication Critical patent/WO2004011496A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Described are polynucleotides encoding novel T-cell proteins and biologically fragments thereof, which are specifically up-regulated during early events in T-cell activation. Furthermore, vectors are described comprising said polynucleotides and/or host cells transformed therewith. Additionally, antisense constructs to said polynucleotides are described. Furthermore, methods and uses for modulating immune responses through the T-cell protein as well as pharmaceutical compositions comprising agents which act on the T-cell protein are described. Also, uses of said polynucleotides, vectors, proteins or antibodies for the preparation of diagnostic and pharmaceutical compositions for use, inter alia, in organ transplantation, for the treatment of autoimmune, allergic or infectious diseases, or for treatment of tumors are provided.
PCT/EP2002/007440 2002-07-04 2002-07-04 Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof WO2004011496A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02758310A EP1581554A2 (en) 2002-07-04 2002-07-04 Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof
AU2002325299A AU2002325299A1 (en) 2002-07-04 2002-07-04 Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof
PCT/EP2002/007440 WO2004011496A2 (en) 2002-07-04 2002-07-04 Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2002/007440 WO2004011496A2 (en) 2002-07-04 2002-07-04 Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof

Publications (2)

Publication Number Publication Date
WO2004011496A2 WO2004011496A2 (en) 2004-02-05
WO2004011496A3 true WO2004011496A3 (en) 2005-10-27

Family

ID=30775771

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/007440 WO2004011496A2 (en) 2002-07-04 2002-07-04 Novel t-cell proteins, peptides and antibodies derived therefrom and uses thereof

Country Status (3)

Country Link
EP (1) EP1581554A2 (en)
AU (1) AU2002325299A1 (en)
WO (1) WO2004011496A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383799B2 (en) 2006-01-20 2013-02-26 Cell Signaling Technology, Inc. Translocation and mutant ROS kinase in human non-small cell lung carcinoma
DK1973946T3 (en) * 2006-01-20 2015-06-22 Cell Signaling Technology Inc TRANSLOCATION AND MUTANT ROSE KINASE IN HUMAN NON-SMALL CELL LUNGCARCINOM

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980281A (en) 1988-02-10 1990-12-25 Housey Gerard M Method of screening for protein inhibitors and activators

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HEINEMAN T ET AL: "GENOMIC ORGANIZATION OF THE GENE CODING FOR TIRC7, A NOVEL MEMBRANEPROTEIN ESSENTIAL FOR T CELL ACTIVATION", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 57, no. 3, 1 May 1999 (1999-05-01), pages 398 - 406, XP000999606 *
See also references of EP1581554A2 *
UTKU N ET AL: "PREVENTION OF ACUTE ALLOGRAFT REJECTION BY ANTIBODY TARGETING OF TIRC7, A NOVEL T CELL MEMBRANE PROTEIN", IMMUNITY, CELL PRESS, US, vol. 9, October 1998 (1998-10-01), pages 509 - 518, XP002188110 *
UTKU N ET AL: "THE HUMAN HOMOLOG OF DROSOPHILA CORNICHON PROTEIN IS DIFFERENTIALLYEXPRESSED IN ALLOACTIVATED T-CELLS", BIOCHIMICA ET BIOPHYSICA ACTA, AMSTERDAM, NL, vol. 1449, no. 3, 1999, pages 203 - 210, XP000982809, ISSN: 0006-3002 *

Also Published As

Publication number Publication date
EP1581554A2 (en) 2005-10-05
WO2004011496A2 (en) 2004-02-05
AU2002325299A1 (en) 2004-02-16

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