WO2003106627A3 - Cancer-linked gene as target for chemotherapy - Google Patents

Cancer-linked gene as target for chemotherapy Download PDF

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Publication number
WO2003106627A3
WO2003106627A3 PCT/US2003/018533 US0318533W WO03106627A3 WO 2003106627 A3 WO2003106627 A3 WO 2003106627A3 US 0318533 W US0318533 W US 0318533W WO 03106627 A3 WO03106627 A3 WO 03106627A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
disclosed
target
chemotherapy
linked gene
Prior art date
Application number
PCT/US2003/018533
Other languages
French (fr)
Other versions
WO2003106627A2 (en
Inventor
Krista Evans
Reinhard Ebner
Original Assignee
Avalon Pharmaceuticals
Krista Evans
Reinhard Ebner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avalon Pharmaceuticals, Krista Evans, Reinhard Ebner filed Critical Avalon Pharmaceuticals
Priority to AU2003276643A priority Critical patent/AU2003276643A1/en
Publication of WO2003106627A2 publication Critical patent/WO2003106627A2/en
Publication of WO2003106627A3 publication Critical patent/WO2003106627A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypetides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agent thereto. Also described are methods of diagnosing using the gene sequences.
PCT/US2003/018533 2002-06-13 2003-06-12 Cancer-linked gene as target for chemotherapy WO2003106627A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003276643A AU2003276643A1 (en) 2002-06-13 2003-06-12 Cancer-linked gene as target for chemotherapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38867302P 2002-06-13 2002-06-13
US60/388,673 2002-06-13

Publications (2)

Publication Number Publication Date
WO2003106627A2 WO2003106627A2 (en) 2003-12-24
WO2003106627A3 true WO2003106627A3 (en) 2004-06-24

Family

ID=29736512

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/018533 WO2003106627A2 (en) 2002-06-13 2003-06-12 Cancer-linked gene as target for chemotherapy

Country Status (2)

Country Link
AU (1) AU2003276643A1 (en)
WO (1) WO2003106627A2 (en)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KAMBE M: "Enhancement of chemotherapeutic effects with focused shock waves: extracorporeal shock wave chemotherapy (ESWC)", IN VIVO, vol. 10, no. 3, 1996, pages 369 - 375, XP002976709 *
OZOREN N AND EL-DEIRY W: "Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis", EXPERIMENTAL CELL RESEARCH, vol. 281, no. 2, 2002, pages 175 - 181, XP002976708 *

Also Published As

Publication number Publication date
WO2003106627A2 (en) 2003-12-24
AU2003276643A8 (en) 2003-12-31
AU2003276643A1 (en) 2003-12-31

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