WO2003097802A3 - Cancer-linked gene as target for chemotherapy - Google Patents

Cancer-linked gene as target for chemotherapy Download PDF

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Publication number
WO2003097802A3
WO2003097802A3 PCT/US2003/015313 US0315313W WO03097802A3 WO 2003097802 A3 WO2003097802 A3 WO 2003097802A3 US 0315313 W US0315313 W US 0315313W WO 03097802 A3 WO03097802 A3 WO 03097802A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
target
disclosed
chemotherapy
linked gene
Prior art date
Application number
PCT/US2003/015313
Other languages
French (fr)
Other versions
WO2003097802A2 (en
Inventor
Zoe Weaver
Reinhard Ebner
Original Assignee
Avalon Pharmaceuticals
Zoe Weaver
Reinhard Ebner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avalon Pharmaceuticals, Zoe Weaver, Reinhard Ebner filed Critical Avalon Pharmaceuticals
Priority to AU2003229293A priority Critical patent/AU2003229293A1/en
Priority to EP03726880A priority patent/EP1513951A4/en
Priority to CA002485981A priority patent/CA2485981A1/en
Publication of WO2003097802A2 publication Critical patent/WO2003097802A2/en
Publication of WO2003097802A3 publication Critical patent/WO2003097802A3/en
Priority to US11/599,845 priority patent/US20080025981A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
PCT/US2003/015313 2002-03-04 2003-05-15 Cancer-linked gene as target for chemotherapy WO2003097802A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2003229293A AU2003229293A1 (en) 2002-05-16 2003-05-15 Cancer-linked gene as target for chemotherapy
EP03726880A EP1513951A4 (en) 2002-05-16 2003-05-15 Cancer-linked gene as target for chemotherapy
CA002485981A CA2485981A1 (en) 2002-05-16 2003-05-15 Cancer-linked gene as target for chemotherapy
US11/599,845 US20080025981A1 (en) 2002-03-04 2006-11-15 Cancer-linked genes as targets for chemotherapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38091202P 2002-05-16 2002-05-16
US60/380,912 2002-05-16

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10514533 A-371-Of-International 2003-05-15
US11/599,845 Continuation-In-Part US20080025981A1 (en) 2002-03-04 2006-11-15 Cancer-linked genes as targets for chemotherapy

Publications (2)

Publication Number Publication Date
WO2003097802A2 WO2003097802A2 (en) 2003-11-27
WO2003097802A3 true WO2003097802A3 (en) 2004-12-29

Family

ID=29550036

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/015313 WO2003097802A2 (en) 2002-03-04 2003-05-15 Cancer-linked gene as target for chemotherapy

Country Status (4)

Country Link
EP (1) EP1513951A4 (en)
AU (1) AU2003229293A1 (en)
CA (1) CA2485981A1 (en)
WO (1) WO2003097802A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2537859A1 (en) 2011-06-23 2012-12-26 Université de Mons Molecules specifically binding pancreatic beta cells biomarkers
EP3672990A1 (en) 2017-08-25 2020-07-01 Five Prime Therapeutics, Inc. B7-h4 antibodies and methods of use thereof
SG11202008105RA (en) 2018-03-02 2020-09-29 Five Prime Therapeutics Inc B7-h4 antibodies and methods of use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094409A2 (en) * 2000-06-07 2001-12-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of pancreatic cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1190051A2 (en) * 1999-06-17 2002-03-27 Incyte Genomics, Inc. Human transport proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094409A2 (en) * 2000-06-07 2001-12-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of pancreatic cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1513951A4 *

Also Published As

Publication number Publication date
AU2003229293A1 (en) 2003-12-02
EP1513951A4 (en) 2005-12-28
AU2003229293A8 (en) 2003-12-02
CA2485981A1 (en) 2003-11-27
EP1513951A2 (en) 2005-03-16
WO2003097802A2 (en) 2003-11-27

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