WO2003102164A3 - Genes lies au cancer utilises comme cibles de chimiotherapie - Google Patents

Genes lies au cancer utilises comme cibles de chimiotherapie

Info

Publication number
WO2003102164A3
WO2003102164A3 PCT/US2003/017920 US0317920W WO03102164A3 WO 2003102164 A3 WO2003102164 A3 WO 2003102164A3 US 0317920 W US0317920 W US 0317920W WO 03102164 A3 WO03102164 A3 WO 03102164A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
target
disclosed
chemotherapy
linked gene
Prior art date
Application number
PCT/US2003/017920
Other languages
English (en)
Other versions
WO2003102164A2 (fr
Inventor
Martin Shea
Reinhard Ebner
Original Assignee
Avalon Pharmaceuticals
Martin Shea
Reinhard Ebner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avalon Pharmaceuticals, Martin Shea, Reinhard Ebner filed Critical Avalon Pharmaceuticals
Priority to AU2003240572A priority Critical patent/AU2003240572A1/en
Publication of WO2003102164A2 publication Critical patent/WO2003102164A2/fr
Publication of WO2003102164A3 publication Critical patent/WO2003102164A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne de séquences de gènes liés au cancer et des séquences d'acides aminés dérivées, ainsi que des méthodes destinées à analyser des agents antitumoraux potentiels compte tenu de leur pouvoir de modulation de l'expression des gènes liés au cancer. L'invention concerne également des anticorps qui réagissent avec les polypeptides de l'invention et des méthodes d'utilisation de ces anticorps pour le traitement d'états cancéreux, par exemple pour le ciblage de cellules cancéreuses in vivo dans le but de leur administrer des agents thérapeutiques. Sont également décrites des méthodes de diagnostic à l'aide des séquences de gènes de l'invention.
PCT/US2003/017920 2002-05-30 2003-05-29 Genes lies au cancer utilises comme cibles de chimiotherapie WO2003102164A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003240572A AU2003240572A1 (en) 2002-05-30 2003-05-29 Cancer-linked gene as target for chemotherapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38436702P 2002-05-30 2002-05-30
US60/384,367 2002-05-30

Publications (2)

Publication Number Publication Date
WO2003102164A2 WO2003102164A2 (fr) 2003-12-11
WO2003102164A3 true WO2003102164A3 (fr) 2005-04-21

Family

ID=29712020

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/017920 WO2003102164A2 (fr) 2002-05-30 2003-05-29 Genes lies au cancer utilises comme cibles de chimiotherapie

Country Status (2)

Country Link
AU (1) AU2003240572A1 (fr)
WO (1) WO2003102164A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 29 January 2002 (2002-01-29), KIKUNO R. ET AL: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro", XP002903261, Database accession no. (AB028982) *
DATABASE GENBANK [online] 8 February 2001 (2001-02-08), SHIMKETS RA ET AL: "Novel nucleic acids and peptides derived from open reading frame X, useful for treating e.g. cancers, proliferative disorders, neurodegenerative disorders and cardiovascular disease", XP002903260, Database accession no. (AAC76569) *
DNA RES., vol. 6, no. 3, 1999, pages 197 - 205 *
HAMPE ET AL: "The genes for the human VPS10 domain-containing receptors are large and contain many small exons", HUMAN GENETICS, vol. 108, no. 6, 2001, pages 529 - 536, XP002294173 *
KIKUNO R. ET AL: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro", DNA RESEARCH, vol. 6, no. 3, 1999, pages 197 - 205, XP002952960 *

Also Published As

Publication number Publication date
WO2003102164A2 (fr) 2003-12-11
AU2003240572A1 (en) 2003-12-19
AU2003240572A8 (en) 2003-12-19

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