WO2003101328A1 - Appareil et procede associe permettant de traiter des lesions cutanees - Google Patents

Appareil et procede associe permettant de traiter des lesions cutanees Download PDF

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Publication number
WO2003101328A1
WO2003101328A1 PCT/IT2003/000347 IT0300347W WO03101328A1 WO 2003101328 A1 WO2003101328 A1 WO 2003101328A1 IT 0300347 W IT0300347 W IT 0300347W WO 03101328 A1 WO03101328 A1 WO 03101328A1
Authority
WO
WIPO (PCT)
Prior art keywords
cannula
sucking
laser
radiofrequency
laser source
Prior art date
Application number
PCT/IT2003/000347
Other languages
English (en)
Inventor
Giuseppe Guantera
Mario Marino
Original Assignee
Akropolis S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akropolis S.R.L. filed Critical Akropolis S.R.L.
Priority to AU2003242995A priority Critical patent/AU2003242995A1/en
Publication of WO2003101328A1 publication Critical patent/WO2003101328A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00559—Female reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/183—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves characterised by the type of antenna
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/183—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves characterised by the type of antenna
    • A61B2018/1846—Helical antennas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/007—Aspiration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/007—Aspiration
    • A61B2218/008—Aspiration for smoke evacuation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy

Definitions

  • the present invention relates to an apparatus for treating cutaneous injuries.
  • the invention concerns an apparatus of the above kind, and the relevant method, to be use in the medical and therapeutical field, based on the use of the combined action of laser, ultrasounds, radiofrequency and negative ions.
  • cicatrix are an more or less serious anaesthetic that, even not a physical invalidation, can be for the person a remarkable psychological problem, particularly if the wound is on the face or on a part of the body usually and periodically exposed, such as shoulders, arms, legs, hands.
  • the Applicant has realised an apparatus, and the relevant method, based on the combination of a plurality of principles, each one aimed to a specific action suitable to obtain specific bio-physical effects on the cutaneous surface affected by the wound.
  • the solution suggested according to the present invention is based on the fact that the wound to be subjected to treatment is generally comprised of a cicatricial tissue that replaced, during the reparatory phase following the wound, the pre-existing epithelial tissue, so that the operations suggested according to the invention are, in succession, the removal of the cicatricial tissue and the stimulation of creation of tissue comprised of epithelial cells, thus having the same features of those before the wound.
  • a very slightly bleeding surface wound similar to an abrasion is obtained, involving only the corneous layer.
  • this new wound is immediately and in the following days subjected to treatment by substances helping in the formation of epithelial tissue, activated by the use of ultrasounds and radiation at the same time of laser and radiofrequency.
  • the use of ultrasounds aims to reduce the inflammation and at the same time help the penetration and the intra-tissue spreading of the substances used, the laser radiation stimulates the reconstruction processes and the radiofrequency induction is used for the known capability of stimulating the production of elastin and collagen, that are the basic bricks of the cutaneous tissue structure.
  • treatments according to the invention can also be carried out according to a sucked phase, or to a pulsed pressure, alternating sucking moments and intervals at room pressure.
  • the apparatus suggested according to the present invention allows to widen the medical - surgical instrument range relevant to the plastic surgery and aesthetic medicine fields.
  • the apparatus suggested is suitable for the ambulatory treatment of cicatrix, stretch marks, cheloids or other surgical or traumatic, pathological wounds and is based on the use of a infrared laser source, a negative ion flow generator, an ultrasound transducer and a radiofrequency emitter.
  • Treatments by the apparatus according to the invention are carried out in two phases, a preparatory phase, aiming to ablate the surface cicatricial tissue and a following phase that, by the combined action of the laser, of the ultrasounds and of the radiofrequency stimulate the reconstruction of the wound by new tissue of the epithelial kind, equal to that already existing before the original wound.
  • the two phases must be carried out with two different boxes having a single laser source.
  • the solution suggested according to the present invention allows to obtain a remarkable practicality and safe, being further very simple under the constructive point of view and under the adjustment of the various components.
  • the apparatus according to the invention is characterised by low manufacturing and operation costs. It is therefore specific object of the present invention an apparatus for treating cutaneous injuries comprising a first structure for exfoliation and sucking of cells and a second structure for reconstruction of epithelial tissue, said first structure providing a laser source, a box having a body with a central longitudinal hole for the passage of the laser beam, and electric coupler, provided within said longitudinal central hole, a pneumatic insulator, a cannula, an ionising device electrode exiting from the cannula, within said cannula, and sucking means for the ablated cells; said second structure providing a laser source, a box having a body with a longitudinal central hole for the passage of the laser beam, a pneumatic insulator, a disposable cannula, means for sucking the ablated cells, an antenna, a piezoelectric element and an ultrasound coupler; the apparatus further providing a sucking and filtering block for the sucked particles, a low voltage and low intensity current feeder,
  • said sucking block provides a sucking pump able to produce vacuum with values included in the range of 0 - 760 mmHg.
  • said high tension generator produces a current adjustable up to 1 0 kV, with a current intensity not higher than 0.05 mA.
  • said radiofrequency generator produces radiofrequency at 3 kHz, with the power that can be adjusted.
  • said second structure is comprised by a handle, with a mechanical coupling for the coupling with interchangeable boxes.
  • the laser source of the two structures can be unified, the remaining components of the structures being coupable to the other parts of the apparatus.
  • said antenna is of the spiral kind.
  • said disposable cannula is a glass disposable or sterilizable cannula.
  • said electrode projecting from the cannula is a pointed disposable or sterilizable electrode.
  • said ultrasound coupler can be comprised of a reversed metallic cone.
  • the invention further concern a method for treating cutaneous injuries comprising a preparation phase, aiming to remove the cicatricial surface tissue and a following phase that, by the combined action of the laser, of the ultrasounds and of the radiofrequency stimulates the reconstruction of the wound with a new epithelial kind tissue, equal to that already existing before the original wound.
  • figure 1 is a schematic view of the box of the apparatus according to the invention in a first treatment phase
  • figure 2 is a schematic view of the box of the apparatus according to the invention in a second treatment phase
  • figure 3 is a first block diagram of the apparatus according to the invention
  • figure 4 is a second block diagram of the apparatus according to the invention.
  • the apparatus substantially provides two blocks, namely a first block providing inside a sucking pump that can produce an atmospheric vacuum between 0 and 760 mmHg, a Laser source feeder, a high tension generator, adjustable up to 1 ,0 kV, with a current intensity not higher than 0.05 mA and a radiofrequency generator at 3 kHz, with adjustable power. Said frequency is not critical, but it has been chosen to obtain the emission of ultrasounds having a surface action on the tissues subjected to treatment by a piezoelectric ceramic.
  • the second block is comprised of a handeable movable laser source, with mechanical coupling for the connection with interchangeable boxes.
  • first figure 1 it is shown the structure of the box comprising the handle to carry out the first phase of the treatment, in order to obtain an exfoliation of the surface of the wound.
  • body 1 of the box is holed along its axis, to allow the fixing of the glass disposable or sterilizable cannula 2, comprising the interface between the system and the part of the body to be subjected to treatment.
  • Box 1 further provides a pneumatic insulator 9, that is comprised of a plane lens transparent to the laser radiation.
  • the function of the insulator 9 is that of realising a pneumatic insulation, in such a way that the laser source 7 can work at atmospheric pressure, thus not being subjected to pressure rushes that could damage the same.
  • FIG. 2 it is schematically shown the structure of the apparatus according to the invention for carrying out the second phase or reconstruction phase.
  • the body 1 comprised of a suitable plastic material, there are provided, along the longitudinal hole 3, glass or plastic cannula 2, providing inside a spiral antenna 9, for the induction of the radiofrequency signal to the part subjected to the treatment.
  • the fact that the end portion of the antenna 9 is a spiral antenna is not a basic feature to obtain the working frequency, but it only has the function of widening the diffusion ray of the signal induced by capacitive effect.
  • Said antenna 9 is removably coupled with a reversed metallic cone 10, coupled with the radiofrequency generator (not shown).
  • Antenna 9 has the object of contacting the radiofrequency signal with the toroidal piezometric ceramic element 1 1 for the generation of the ultrasonic vibration, transmitted by the same cone to the cannula 2.
  • Signal transmitted from the antenna 9 has the same frequency of the ultrasound signal, since both the antenna and the piezoelectric ceramic element 1 1 are supplied by the same generator.
  • Sleeve 8 allows the coupling of the box with the sucking system and is angled with respect to the body axis 1 , to prevent that possible sucked particles can soil the optical parts of the laser.
  • Body face 1 opposed to that from which the cannula 2 exits is closed by the lens 9, that let the laser ray 6 passing and insulates the block comprised of the radiofrequency generator for the excitation of the piezoelectric ceramic element 1 1 and for supplying the antenna.
  • box A for the first phase treatment (shown in figure 1 ) is coupled with blocks B, C and D.
  • Generator shown in figures 3 and 4 is comprised of four blocks:
  • - block B comprised of a sucking pump and relevant particle interception filter
  • - block C comprised of the feeder of the Laser source
  • - block D comprised of the high tension and low intensity current feeder for producing the negative ion flow
  • block E comprised of radiofrequency generator for excitation of the piezoelectric ceramic element 1 1 and for supplying the antenna 9.
  • the functional part of the solution suggested according to the invention is focused on two handles, respectively carrying out the functions of exfoliation and suction of the cells, so that they must be realised very carefully.
  • the treatment that can be carried out by the apparatus according to the invention provides two phases, respectively an exfoliation and a reconstruction phase, both providing the use of a laser, the latter becomes a common element.
  • the handle for treatments substantially provides the LASER source fixedly coupled with the generator, and two separated boxes provided with a suitable optical, mechanical coupling system between the boxes and the same source.
  • the treatment is mainly carried out under sucking conditions, and the laser source is provided with delicate alignment systems of the optical cavity, is unavoidable that it is not subjected to stresses due to the pressure, that could damage the same.
  • the treatment boxes are pneumatically insulated with respect to the laser source in such a way that the latter can work exclusively under atmospheric room pressure.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Otolaryngology (AREA)
  • Electromagnetism (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Surgical Instruments (AREA)
  • Laser Surgery Devices (AREA)

Abstract

L'invention concerne un appareil permettant de traiter des lésions cutanées, comprenant une première structure d'exfoliation et d'aspiration de cellules et une seconde structure pour la reconstruction du tissu épithélial. La première structure comporte une source laser, un boîte possédant un corps avec un trou longitudinal central destiné au passage du faisceau laser, et un dispositif d'accouplement électrique situé dans le trou central longitudinal, un isolateur pneumatique, une canule, une électrode d'ionisation du dispositif sortant de la canule et située dans la canule, et un moyen d'aspiration pour les cellules enlevées. La seconde structure comporte une source laser, une boîte possédant un corps avec un trou central longitudinal destiné au passage du faisceau laser, un isolateur pneumatique, une canule jetable, un moyen d'aspiration pour les cellules enlevées, une antenne, un élément piézo-électrique et un dispositif d'accouplement à ultrasons. L'appareil comporte également un bloc d'aspiration et de filtrage pour les particules aspirées, une ligne d'alimentation de courant à faible tension et à faible intensité destinée à produire un flux ionique négatif, et un générateur de radiofréquences destiné à exciter l'élément céramique piézo-électrique.
PCT/IT2003/000347 2002-06-03 2003-06-03 Appareil et procede associe permettant de traiter des lesions cutanees WO2003101328A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003242995A AU2003242995A1 (en) 2002-06-03 2003-06-03 Apparatus and relevant method for treating cutaneous injuries

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002RM000307A ITRM20020307A1 (it) 2002-06-03 2002-06-03 Apparecchiatura per il trattamento di lesioni cutanee, e relativo metodo.
ITRM2002A000307 2002-06-03

Publications (1)

Publication Number Publication Date
WO2003101328A1 true WO2003101328A1 (fr) 2003-12-11

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Family Applications (1)

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PCT/IT2003/000347 WO2003101328A1 (fr) 2002-06-03 2003-06-03 Appareil et procede associe permettant de traiter des lesions cutanees

Country Status (3)

Country Link
AU (1) AU2003242995A1 (fr)
IT (1) ITRM20020307A1 (fr)
WO (1) WO2003101328A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007113817A3 (fr) * 2006-04-06 2007-11-15 Lite Touch Ltd Procédés et appareil de photothermolyse
WO2007147905A1 (fr) * 2006-06-16 2007-12-27 Arcusa Villacampa Francisco Ja Aiguille jetable améliorée pour application d'énergie laser
EP1991315A1 (fr) * 2006-02-28 2008-11-19 Jun, Yong gyu Applicateur pour traitement de la peau et procédé de traitement de la peau mettant en oeuvre ledit applicateur

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0310431A2 (fr) * 1987-09-30 1989-04-05 Valleylab, Inc. Appareil pour la fragmentation de tissus et/ou hémostase
US5702360A (en) * 1993-07-08 1997-12-30 Satelec S.A. Ultrasonic surgical knife
WO2001049194A2 (fr) * 1999-12-30 2001-07-12 Pearl Technology Holdings, Llc Dispositif de lifting facial
US20010014780A1 (en) * 1999-05-14 2001-08-16 Martin Roy W. Apparatus and method for producing high intensity focused ultrasonic energy for medical applications
FR2805989A1 (fr) * 2000-03-10 2001-09-14 Prod Ella Bache Laboratoire Su Procede de traitement des inesthetismes de la silhouette du corps humain et dispositif pour la mise en oeuvre du procede
US6355033B1 (en) * 1999-06-17 2002-03-12 Vivant Medical Track ablation device and methods of use

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0310431A2 (fr) * 1987-09-30 1989-04-05 Valleylab, Inc. Appareil pour la fragmentation de tissus et/ou hémostase
US5702360A (en) * 1993-07-08 1997-12-30 Satelec S.A. Ultrasonic surgical knife
US20010014780A1 (en) * 1999-05-14 2001-08-16 Martin Roy W. Apparatus and method for producing high intensity focused ultrasonic energy for medical applications
US6355033B1 (en) * 1999-06-17 2002-03-12 Vivant Medical Track ablation device and methods of use
WO2001049194A2 (fr) * 1999-12-30 2001-07-12 Pearl Technology Holdings, Llc Dispositif de lifting facial
FR2805989A1 (fr) * 2000-03-10 2001-09-14 Prod Ella Bache Laboratoire Su Procede de traitement des inesthetismes de la silhouette du corps humain et dispositif pour la mise en oeuvre du procede

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1991315A1 (fr) * 2006-02-28 2008-11-19 Jun, Yong gyu Applicateur pour traitement de la peau et procédé de traitement de la peau mettant en oeuvre ledit applicateur
EP1991315A4 (fr) * 2006-02-28 2012-08-22 Yong Gyu Jun Applicateur pour traitement de la peau et procédé de traitement de la peau mettant en oeuvre ledit applicateur
WO2007113817A3 (fr) * 2006-04-06 2007-11-15 Lite Touch Ltd Procédés et appareil de photothermolyse
WO2007147905A1 (fr) * 2006-06-16 2007-12-27 Arcusa Villacampa Francisco Ja Aiguille jetable améliorée pour application d'énergie laser

Also Published As

Publication number Publication date
ITRM20020307A1 (it) 2003-12-03
AU2003242995A1 (en) 2003-12-19
ITRM20020307A0 (it) 2002-06-03

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