WO2003093300A3 - Peptides anti-microbiens et compositions - Google Patents

Peptides anti-microbiens et compositions Download PDF

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Publication number
WO2003093300A3
WO2003093300A3 PCT/US2003/014240 US0314240W WO03093300A3 WO 2003093300 A3 WO2003093300 A3 WO 2003093300A3 US 0314240 W US0314240 W US 0314240W WO 03093300 A3 WO03093300 A3 WO 03093300A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
microbial peptides
cyclic peptides
acids
peptides
Prior art date
Application number
PCT/US2003/014240
Other languages
English (en)
Other versions
WO2003093300A2 (fr
Inventor
M Reza Ghadiri
Hui Sun Kim
Sara Fernandez-Lopez
Keith Wilcoxen
Original Assignee
Scripps Research Inst
M Reza Ghadiri
Hui Sun Kim
Sara Fernandez-Lopez
Keith Wilcoxen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2002/014329 external-priority patent/WO2002090503A2/fr
Application filed by Scripps Research Inst, M Reza Ghadiri, Hui Sun Kim, Sara Fernandez-Lopez, Keith Wilcoxen filed Critical Scripps Research Inst
Priority to AU2003228896A priority Critical patent/AU2003228896A1/en
Publication of WO2003093300A2 publication Critical patent/WO2003093300A2/fr
Publication of WO2003093300A3 publication Critical patent/WO2003093300A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne de nouveaux agents anti-microbiens et des compositions qui incluent des peptides cycliques portant une séquence d'acides aminés faisant alterner les acides aminés L et D. Selon un autre mode de réalisation, les peptides cycliques sont faits d'acides aminés β.
PCT/US2003/014240 2002-05-06 2003-05-06 Peptides anti-microbiens et compositions WO2003093300A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003228896A AU2003228896A1 (en) 2002-05-06 2003-05-06 Anti-microbial peptides and compositions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
USPCT/US02/14329 2002-05-06
PCT/US2002/014329 WO2002090503A2 (fr) 2001-05-04 2002-05-06 Peptides antimicrobiens et compositions

Publications (2)

Publication Number Publication Date
WO2003093300A2 WO2003093300A2 (fr) 2003-11-13
WO2003093300A3 true WO2003093300A3 (fr) 2004-09-10

Family

ID=29398926

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/014240 WO2003093300A2 (fr) 2002-05-06 2003-05-06 Peptides anti-microbiens et compositions

Country Status (2)

Country Link
AU (1) AU2003228896A1 (fr)
WO (1) WO2003093300A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7566765B2 (en) 2000-03-06 2009-07-28 Rigel Pharmaceuticals, Inc. Heterocyclic compounds containing a nine-membered carbon-nitrogen ring
JP2007538112A (ja) 2004-01-29 2007-12-27 ピナクル ファーマシューティカルズ β−シクロデキストリン誘導体およびそれらの炭疽致死毒に対する使用
US20080234182A1 (en) * 2007-03-22 2008-09-25 Innovative Biologics, Inc. Blockers of pore-forming virulence factors and their use as anti-infectives
AU2012203804B2 (en) * 2005-12-22 2014-10-16 Novabiotics Limited Cyclic antimicrobial peptides
NO346186B1 (no) * 2005-12-22 2022-04-11 Novabiotics Ltd Anvendelse av et syklisk peptid for fremstilling av et medikament for behandling eller forebyggelse av en soppinfeksjon.
WO2010051667A1 (fr) * 2008-11-10 2010-05-14 复旦大学 Compositions pharmaceutiques comprenant des nanotubes de peptide cyclique et utilisations de celles-ci

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010535A1 (fr) * 1993-10-14 1995-04-20 The Scripps Research Institute Tube peptidique cyclique

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010535A1 (fr) * 1993-10-14 1995-04-20 The Scripps Research Institute Tube peptidique cyclique

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FERNANDEZ-LOPEZ, ET AL: "ANTIBACTERIAL AGENTS BASED ON THE CYCLIC D,L-ALPHA-PEPTIDE ARCHITECTURE", NATURE, vol. 412, no. 6845, 26 July 2001 (2001-07-26), pages 452 - 455, XP002971654 *
GHADLRI, ET AL: "SELF-ASSEMBLING ORGANIC NANOTUBES BASED ON A CYCLIC PEPTIDE ARCHITECTURE", NATURE, vol. 366, 25 November 1993 (1993-11-25), pages 324 - 327, XP002936460 *
RAPAPORT, ET AL: "CRYSTALLINE CYCLIC PEPTIDE NANOTUBES AT INTERFACE", J. AM. CHEM. SOC., vol. 121, 1999, pages 1186 - 1191, XP002971655 *

Also Published As

Publication number Publication date
WO2003093300A2 (fr) 2003-11-13
AU2003228896A8 (en) 2003-11-17
AU2003228896A1 (en) 2003-11-17

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