WO2003088873A1 - Bande de fixation permettant de fixer une valvule cardiaque prothetique a un tissu - Google Patents

Bande de fixation permettant de fixer une valvule cardiaque prothetique a un tissu Download PDF

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Publication number
WO2003088873A1
WO2003088873A1 PCT/US2003/011702 US0311702W WO03088873A1 WO 2003088873 A1 WO2003088873 A1 WO 2003088873A1 US 0311702 W US0311702 W US 0311702W WO 03088873 A1 WO03088873 A1 WO 03088873A1
Authority
WO
WIPO (PCT)
Prior art keywords
proximal
distal
annular portion
fixation band
tissue
Prior art date
Application number
PCT/US2003/011702
Other languages
English (en)
Inventor
Steven B. Woolfson
Richard B. Streeter
Daniel C. Taylor
John R. Liddicoat
Original Assignee
Viacor, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viacor, Inc. filed Critical Viacor, Inc.
Priority to AU2003230938A priority Critical patent/AU2003230938A1/en
Publication of WO2003088873A1 publication Critical patent/WO2003088873A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes

Definitions

  • This invention relates to surgical apparatus in general, and more particularly to prosthetic heart valves.
  • the human heart consists of four chambers: the right atrium for receiving blood from systemic circulation; the right ventricle for receiving blood from the right atrium and pumping it to the lungs; the left atrium for receiving oxygenated blood from the lungs; and the left ventricle for receiving oxygenated blood from the left atrium and pumping it to systemic circulation.
  • the human heart also consists of four valves: the tricuspid valve located between the right atrium and the right ventricle; the pulmonary valve located at the output of the right ventricle; the mitral valve located between the left atrium and the left ventricle; and the aortic valve located at the output of the left ventricle.
  • a natural heart valve may need to be replaced by a prosthetic heart valve.
  • the patient In this situation, sometimes referred to as "on pump" surgery, the patient must be placed on a heart-lung machine and the heart stopped while the defective heart valve is removed and the prosthetic heart valve installed through a major incision made in the wall of the heart.
  • the prosthetic heart valve is typically sutured in place at the annulus, or seat, of the natural heart valve using a sewing cuff disposed about the circular periphery of the prosthetic heart valve.
  • the incisions may be made into the vascular system at a location remote from the valve seat, e.g., in the superior vena cava in the case of the tricuspid valve, or in the pulmonary artery in the case of the pulmonary valve, or the pulmonary veins in the case of the mitral valve, or the aorta in the case of the aortic valve.
  • one object of the present invention is to provide novel apparatus for quickly, easily and conveniently affixing a prosthetic heart valve in position within the heart.
  • Another object of the present invention is to provide a novel fixation band for affixing a prosthetic heart valve in position within the heart. And another object of the present invention is to provide a novel method for affixing a prosthetic heart valve in position within the heart.
  • the fixation band generally comprises a tubular frame having a distal end and a proximal end, and a tube having a distal end and a proximal end.
  • the tubular frame comprises a plurality of longitudinally-extending members each having a hook on its distal end and
  • the tubular frame also comprises at least one laterally-extending member for stabilizing the longitudinally-extending members relative to one another so as to form the complete tubular frame.
  • the tube is positioned inside the longitudinally-extending members, with the distal end of the tube being everted back over the aforementioned hooks.
  • a sewing cuff is formed in the tube distal to the distalmost end of the longitudinally-extending members.
  • a standard prosthetic valve is secured to the distal end of the fixation band by suturing the prosthetic valve' s sewing cuff to the fixation band' s sewing cuff.
  • the prosthetic valve, with fixation band attached is advanced to the valve's seat.
  • the fixation band' s tubular frame is pulled proximally slightly. This action causes the ends of the hooks to pass through the side wall of the everted tube and into the surrounding tissue at the valve's seat, whereby the fixation band, and hence the prosthetic valve, will be fixed against further proximal movement.
  • the fixation band' s fixation means are deployed so as to
  • VIA-2425 secure the proximal end of the fixation band to the surrounding tissue, whereby the fixation band, and hence the prosthetic valve, will be fixed against distal movement.
  • the fixation means may be deployed by bending them radially outwardly so that they engage the surrounding tissue.
  • the fixation means may be deployed by removing a restraining device, whereby the fixation means will automatically deploy against the surrounding tissue.
  • a fixation band for affixing a prosthetic heart valve to tissue
  • the fixation band comprising: a structure having a proximal end and a distal end in opposition to one another, and a lateral region between the proximal end and the distal end, wherein the prosthetic heart valve is attached to one of the proximal end and the distal end of the structure; a plurality of barbs selectively configurable between a first position and a second position, the barbs being contained within a peripheral boundary of the lateral
  • VIA-2425 region of the structure in the first position and the barbs being extended from the peripheral boundary of the lateral region of the structure in the second position; and an actuator for selectively moving the plurality of barbs between the first position and the second position.
  • a prosthetic heart valve assembly comprising: a prosthetic heart valve comprising a frame, at least one leaflet adapted to open and close relative to the frame; and a fixation band for affixing the prosthetic heart valve to tissue, the fixation band comprising: a structure having a proximal end and a distal end in opposition to one another, and a lateral region between the proximal end and the distal end, wherein the prosthetic heart valve is attached to one of the proximal end and the distal end of the structure; a plurality of barbs selectively configurable between a first position and a second position, the barbs being contained within a peripheral boundary of the lateral region of the structure in the first position, and the barbs being extended from the peripheral boundary of
  • a method for affixing a prosthetic heart valve to tissue comprising: providing a fixation band for affixing a prosthetic heart valve to tissue, the fixation band comprising: a structure having a proximal end and a distal end in opposition to one another, and a lateral region between the proximal end and the distal end, wherein the prosthetic heart valve is attached to one of the proximal end and the distal end of the structure; a plurality of barbs selectively configurable between a first position and a second position, the barbs being contained within a peripheral boundary of the lateral region of the structure in the first position, and the barbs being extended from the peripheral boundary of the lateral region of the structure in the second position; and an actuator for selectively moving the plurality of barbs between the first position and the second
  • VIA-2425 fixation band adjacent to the tissue and actuating the fixation band so as to affix the prosthetic valve to tissue.
  • a method for affixing a prosthetic heart valve to tissue comprising: positioning a fixation band adjacent to the tissue; and removing a pin in engagement with a spring in a loaded configuration so as to release the spring, cause a cog to rotate, and deploy barbs through a lateral portion of the fixation band into the tissue surrounding the fixation band.
  • a fixation band for affixing a prosthetic heart valve to tissue
  • the fixation band comprising: a proximal annular portion and a distal annular portion selectively positioned relatively to one another, the proximal annular portion and the distal annular portion each having a proximal side and a distal side, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and the prosthetic heart
  • VIA-2425 valve being attached to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; a plurality of staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device in attachment to the proximal annular portion and the distal annular portion, the compression device being configured to selectively position the proximal annular member and the distal annular member toward one another so as to compress the plurality of staples therebetween and deploy the plurality of staples into tissue so as to affix the prosthetic heart valve to the tissue.
  • a prosthetic heart valve assembly comprising: a prosthetic heart valve comprising a frame, and at least one leaflet adapted to open and close relative to the frame; and a fixation band for affixing a prosthetic heart valve to tissue, the fixation band comprising: a proximal annular portion and a distal annular portion selectively positioned relatively to one another, the proximal annular portion and the fixation band
  • VIA-2425 distal annular portion each having a proximal side and a distal side, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and the prosthetic heart valve being attached to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; a plurality of staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device in attachment to the proximal annular portion and the distal annular portion, the compression device being configured to selectively position the proximal annular member and the distal annular member toward one another so as to compress the plurality of staples therebetween and deploy the plurality of staples into tissue so as to affix the prosthetic heart valve to the tissue.
  • a method for affixing a prosthetic heart valve to tissue comprising: providing a fixation band for affixing a prosthetic heart valve to tissue, the fixation band comprising: a proximal annular
  • a method for affixing a prosthetic heart valve to tissue comprising: positioning a fixation band having the prosthetic heart valve attached thereto adjacent to the tissue; and actuating a compression device attached to the fixation band so as to move a proximal annular portion and a distal annular portion of the fixation band toward one another so as to deploy a plurality of staples into the tissue.
  • a method for affixing a prosthetic heart valve to tissue comprising: positioning a fixation band adjacent to tissue; actuating a compression device attached to the fixation band to move a proximal annular portion and a distal annular portion of the fixation band toward one another so as to deploy a plurality of staples into the tissue; and attaching the prosthetic heart valve to the fixation band.
  • Fig. 1 is a schematic view of a fixation band formed in accordance with the present invention
  • Fig. 2 is a schematic view of the fixation band's tubular frame
  • Fig. 3 is a schematic view of the fixation band's tube prior to its assembly with the tubular frame
  • Fig. 4 is a schematic view of the complete fixation band shown in Fig. 1;
  • Fig. 5 is a schematic view showing a prosthetic heart valve secured to the fixation band of Fig. 1;
  • Fig. 6 is a schematic view showing the assembly of
  • FIG. 7 is a schematic view showing the assembly of Fig. 6 after deployment of the fixation band's proximal fixation means;
  • Fig. 8 is a schematic view showing a restraining device for restraining the fixation band's proximal fixation mean
  • Figs. 9A-12B are schematic views showing a fixation apparatus having side deploying barbs
  • Figs. 13A-13D are schematic views showing a heart valve replacement using the side deploying fixation apparatus shown in Figs. 9A-12B;
  • Figs. 14-30 are schematic views showing fixation apparatus having compression deploying barbs.
  • Figs. 31 and 32 are schematic views showing a heart valve replacement using a left ventrical approach
  • Figs. 33-35 are schematic views showing fixation of an prosthetic aortic heart valve at an annulus of the native aortic valve
  • Figs. 36-39 are schematic views showing fixation of an prosthetic heart valve using snap fit means
  • FIG. 40 is a schematic view showing another embodiment of a prosthetic heart valve using snap fit means .
  • Fixation band 5 which comprises one preferred form of the invention.
  • Fixation band 5 generally comprises a tubular frame 10 and a tube 15.
  • Tubular frame 10 is shown in greater detail in
  • Tubular frame 10 generally comprises a distal end 20 and a proximal end 25.
  • Tubular frame 10 comprises a plurality of longitudinally-extending members 30 each having a hook 35 on its distal end, and fixation means 40 (discussed in further detail below) on its proximal end.
  • Tubular frame 10 also comprises at least one laterally-extending member 45 for stabilizing the longitudinally-extending members 30 relative to one another so as to form the complete tubular frame.
  • each laterally-extending member 45 extends completely around the circumference of the frame, in the manner shown in
  • laterally-extending member 45 may be in the form of a circular hoop, like the hoop of a barrel, such as the laterally-extending member 47 shown in Fig. 2.
  • laterally-extending member 45 may have a serpentine configuration, such as the laterally-extending member 48 shown in Fig. 2.
  • Tube 15 is, initially, an ordinary straight tube such as is shown in Fig. 3, i.e., it is a hollow structure having a distal end 50, a proximal end 55 and a central lumen 60 extending therebetween.
  • Tube 15 is preferably formed out of material which is easily incorporated in tissue, e.g., Dacron polyester or the like.
  • Tube 15 may be vertically pleated or elastic, whereby to allow the material to stretch radially.
  • Tube 15 is preferably mounted to tubular frame 10 as follows. First, the distal end 50 of tube 15 is passed, distally, down the interior of tubular frame 10. Then the distal end 50 of tube 15 is everted (Fig.
  • a sewing cuff 65 is formed in tube 15 distal to the distalmost end of longitudinally-extending members 30.
  • Tube 15 may then be secured in this position, e.g., with sutures 70 maintaining sewing cuff 65 and with sutures 80 holding tube 15 to longitudinally-extending members 30.
  • a standard prosthetic heart valve 85 (Fig. 5) is secured to the distal end of fixation band 5 by sewing the prosthetic heart valve's sewing cuff 90 to the fixation band's sewing cuff 65.
  • the prosthetic valve 85, with fixation band 5 attached is advanced to the valve's seat.
  • the fixation band's tubular frame 10 is pulled proximally slightly. This action causes the ends of the hooks 35 to pass through the side wall of the everted tube 15 (Fig. 6) and into the surrounding tissue T at the valve's seat, whereby fixation band 5, and hence prosthetic valve 85, will be fixed against further proximal movement.
  • the fixation band's fixation means 40 are deployed (Fig. 7) so as to secure the proximal end of the fixation band
  • fixation means 40 are secured to the proximal end of tube 15, the proximal end of tube 15 will follow the curvature of the deploying fixation means 40, such as is shown in Fig. 7.
  • fixation means 40 are free to move independently outboard relative to the proximal end of tube 40, either because they are not secured to tube 15 or they extend past the proximal end of the tube, fixation means 40 are free to move separately into the surrounding tissue.
  • fixation means 40 may be deployed by bending the proximal ends of longitudinally-extending members 30 outwardly, e.g., with an annular forming tool or a forceps-type device.
  • fixation means 40 may be deployed by removing a restraining device, e.g., a collar 87 (Fig. 8), whereby fixation means 40 will automatically deploy against the surrounding tissue.
  • Fixation band 5 may be used to affix prosthetic heart valve 85 to tissue in a conventional on-pump surgical procedure.
  • fixation band 5 may be used to affix prosthetic heart valve 85 to tissue in a beating heart, off-pump surgical procedure.
  • the assembled heart valve 85 and fixation band 5 are advanced to the intended valve seat by passing the assembly through an appropriate vascular pathway, e.g., in the case of the aortic valve, by passing the assembly down the aorta.
  • tubular frame 10 is described as being fully assembled (i.e., laterally-extending member 45 is secured to longitudinally-extending member 30) prior to being joined with tube 15 so as to form the complete fixation band 5.
  • longitudinally-extending members 30 are described as being fully assembled (i.e., laterally-extending member 45 is secured to longitudinally-extending member 30) prior to being joined with tube 15 so as to form the complete fixation band 5.
  • longitudinally-extending members 30 are described as being fully assembled (i.e., laterally-extending member 45 is secured to longitudinally-extending member 30) prior to being joined with tube 15 so as to form the complete fixation band 5.
  • VIA-2425 and/or the laterally-extending member 45 may be secured to tube 15 prior to being joined to one another.
  • tube 15 is described as being, prior to eversion, an ordinary straight tube.
  • tube 15 could be flared outwardly toward its distal end 50 to facilitate eversion over hooks 35, and/or it could include a radially-extending flange at its distal end to facilitate eversion over hooks 35, where the flange may be formed separately from the main body of the tube.
  • Figs. 9A-13D there is shown a side deploying apparatus 90 for affixing an prosthetic aortic heart valve 95 in position inside the aorta.
  • Side deploying apparatus 90 is a multi-state device that can be safely guided into the aorta, properly positioned near the annulus of the native aortic valve, and then, by either automatic action or operator control, be deployed by means of introducing a number of barbs 100 into the aortic valve annulus. Side deploying apparatus 90 may also have the capability of its barbs 100 being retracted for either better positioning or removal.
  • apparatus 90 comprises two shell portions 105 and two cog portions 110.
  • apparatus 90 is shown assembled and its barbs 100 deployed.
  • Fig. 9B apparatus 90 is shown assembled, attached to a prosthetic valve 95 and its barbs 100 deployed, which keeps prosthetic valve 95 stationary relative to the wall of the aorta.
  • Three significant features of shell 105 are: studs 115, which act as anchors for cog 110; the exit tracts 120, which allow for barbs 100 of cog 110 to exit shells 105; and the pinholes 125 through which actuating pins 130 (Fig. 11B) are inserted.
  • cog 110 is shown in a "loaded" form inside shell 105.
  • Two cogs 110 are the moving parts of apparatus 90 and reside sandwiched next to each other inside shells 105, but in opposing directions to one another.
  • cog 110 has several significant features integral to its function: eyelets 135, springs 140, barbs 100, and pinholes 142. When in the loaded state, springs 140 of cog 110 are stretched and barbs 100 are
  • FIGs. 12A and 12B cog 110 is shown in the "deployed" form relative to shell 105.
  • barbs 100 are extended through exit tracts 120 and springs 140 are no longer stretched.
  • Apparatus 90 can be transformed into the deployed state by removing pins 130 from pinholes 142 of each cog 110.
  • springs 140 each contract so as to rotate cog 110 relative to studs 115 of shell 105 and force barbs 100 out of exit tracks 120.
  • force on pinholes 142 must be re-applied and cog 110 rotated back to its loaded position (see Figs. 11A and ' 11B) .
  • FIGs. 13A-13D there is shown an example of a typical heart valve replacement.
  • Fig. 13A there is shown an aorta 145 with a native aortic valve 150.
  • Fig. 13B aorta 145 is shown after valve 150 has been removed.
  • Fig. 13C side deploying apparatus 90 is shown in an undeployed state (see Figs.
  • FIG. 13D side deploying apparatus 90 is shown in a deployed state (see Figs. 12A and 12B) inside aorta 145.
  • side deploying apparatus 90 is described in the context of affixing an prosthetic heart valve 95 in position within the aortic valve annulus. ' In this respect it should also be appreciated, however, that side deploying apparatus 90 may be used to affix some other heart valve within another cardiovascular structure.
  • FIG. 14 an apparatus 155 for affixing an prosthetic aortic valve 160 (Fig. 17) in position inside the aortic valve annulus.
  • Apparatus 155 is a compressive device that can be safely guided into the aorta, properly positioned near the annulus of the native aortic valve, and then, by either automatic action or operator control, deployed by means of advancing staples 165 (Fig. 17) into the aortic valve annulus.
  • Compressive apparatus 155 may also have the capability of having its staples 165 retracted for either better positioning or removal of the apparatus.
  • VIA-2425 apparatus 155 may be positioned for fixation above, below, or at the annulus of the native aortic valve.
  • Compressive apparatus 155 may also be positioned using an aortic approach or a left ventricular approach so as to advance it toward the annulus of the native aortic valve .
  • compressive apparatus 155 comprises a top ring 170 and a bottom ring 175 selectively positionable relative to one another by connector portions 180.
  • Top ring 170 and bottom ring 175 each have a surface, forming an anvil 185, facing one another.
  • each anvil 185 (on top ring 170 and bottom ring 175) is shaped in an opening curve configuration so as to form a "C" shaped staple 165 (see Figs. 19) when deployed.
  • each anvil 185 is shaped with a closing curve so as to form a "B" shaped staple (not shown) when deployed.
  • apparatus 155 includes
  • VIA-2425 deployment means 190 for selectively actuating top ring 170 and bottom ring 175 relative to one another.
  • Deployment means 190 generally comprise a handle 195, a plurality of cables 200 selectively connected to bottom ring 175 and extending to handle 195, and a support 205 selectively engaging top ring 170 and slidably connected to handle 200.
  • support 205 (see Fig. 16) comprises a solid component having passages 210 for blood flow formed therein.
  • support 205 comprises three legs 215 (Fig. 17), which allow blood flow therebetween .
  • a preferred embodiment of the present invention there is shown the compressive apparatus 155 and the prosthetic aortic heart valve 160 in connection to one another. Preferably, this connection is performed prior to implantation, either in an operating room by a physician or a manufacturing site by a manufacturer.
  • apparatus 155 and prosthetic aortic heart are shown in connection to one another.
  • VIA-2425 valve 160 are connected to one another in vivo, either prior to, or subsequent to, the fixation of apparatus 155 at or adjacent to an annulus of a native aortic heart valve (not shown) .
  • apparatus 155 is shown prior to actuation, with top ring 170 and bottom ring 175 spaced apart from one another. While in this configuration, apparatus 155 is positioned at a desired deployment site, at or adjacent to the annulus of the native aortic valve (not shown) .
  • FIGs. 19 and 20 apparatus 155 is shown subsequent to actuation, with top ring 170 and bottom ring 175 having been brought toward one another.
  • staples 165 are deployed in a "C" configuration, extending away from each anvil 185, as top ring 170 and bottom ring 175 are drawn together.
  • This deployment is effected by moving handle 195 ' away from support 205 (while applying a force on support 205 to prevent it from also moving with handle 195) so that cables 200 pull bottom ring 175 toward top ring 170, which is held stationary by legs 215.
  • deployment means 190 are shown disconnected from apparatus 155 and prosthetic aortic valve 160, with apparatus 155 shown configured for attachment at or adjacent to the annulus of a native aortic heart valve (not shown) .
  • Deployment means 190 is configured to disengage from apparatus 155 when handle 195 is moved away from apparatus 155 without holding support 205 stationary; as this occurs, cables 200 withdraw from bottom ring 175 and legs 215, which are pivotally attached together, collapse so that they can be withdrawn through a narrow opening.
  • tubular controller 220 generally comprises a grasper 225 for selective attachment to handle 195, and a tube 230 surrounding grasper 225 for selectively engaging support 205.
  • compression apparatus 155 is to be deployed (i.e., when it is to have its rings 170 and 175 drawn together so as to deform the staples 165)
  • tube 230 is held against support 205 while grasper 225 pulls handle 195 away from support 205.
  • deployment means 190 are to be withdrawn from
  • VIA-2425 compression apparatus 155 tubular controller is withdrawn from compression apparatus 155 by simultaneously withdrawing both grasper 225 and tube 230.
  • Figs. 26-29 there is shown apparatus 155 having a single anvil 185 for forming staple 165 into a "half-c" configuration.
  • apparatus 155 may be configured with a height of about half that of an apparatus 155 that forms a "C" configuration.
  • FIGs. 30-32 in a preferred embodiment of the present invention, there is shown apparatus being placed super-annular, i.e., on the aorta side of the aortic valve.
  • This placement of apparatus 155 superior to the annulus is preferably performed using a left ventricle approach through the heart.
  • a collapsible support 205 may be used.
  • a non-collapsible support (not shown) may be used.
  • a punch 235 may be used to resect the native aortic valve, with the punch approaching from either a left
  • FIGs 33-35 in a preferred embodiment of the present invention, there is shown apparatus 155 being affixed to the annulus of the native heart valve.
  • staples 165 are placed at the annulus so as to hold apparatus 155 in place.
  • a fixation ring 237 is shown with snap fit means 238 for attachment of a prosthetic valve 239 to the fixation ring 237.
  • Fixation ring 237 is deployed adjacent to the annulus of the native aortic valve and prosthesis 239 is snap fit to fixation ring 237 using snap fit means 238.
  • apparatus 155 configured with spring snaps 240 for attachment of a prosthesis 245 to apparatus 155.
  • Prosthesis 245 may be secured to apparatus 155 after attachment of apparatus 155 to the annulus is completed.
  • compressive apparatus 155 is described in the context of affixing a
  • VIA-2425 prosthetic heart valve in position within the aorta may be used to affix some other heart valve within another cardiovascular structure.

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  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention porte sur une bande de fixation (155) permettant de fixer une valvule cardiaque prothétique à un tissu. Cette bande de fixation comprend : une structure dotée d'une extrémité proximale et d'une extrémité distale opposées l'une à l'autre, et une zone latérale située entre l'extrémité proximale et l'extrémité distale, la valvule cardiaque prothétique étant fixée à l'extrémité proximale ou à l'extrémité distale de la structure ; une pluralité de cannelures (165) sélectivement configurables entre une première position et une seconde position, les cannelures (165) étant contenues dans une limite périphérique de la zone latérale de la structure en première position, et les cannelures (165) faisant saillie depuis la limite périphérique de la zone latérale de la structure en seconde position ; et un actionneur permettant de sélectivement déplacer la pluralité des cannelures (165) entre la première position et la seconde position.
PCT/US2003/011702 2002-04-16 2003-04-16 Bande de fixation permettant de fixer une valvule cardiaque prothetique a un tissu WO2003088873A1 (fr)

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Application Number Priority Date Filing Date Title
AU2003230938A AU2003230938A1 (en) 2002-04-16 2003-04-16 Fixation band for affixing a prosthetic heart valve to tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37305902P 2002-04-16 2002-04-16
US60/373,059 2002-04-16

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Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7621948B2 (en) 2003-07-21 2009-11-24 The Trustees Of The University Of Pennsylvania Percutaneous heart valve
US7753949B2 (en) 2007-02-23 2010-07-13 The Trustees Of The University Of Pennsylvania Valve prosthesis systems and methods
US8070802B2 (en) 2007-02-23 2011-12-06 The Trustees Of The University Of Pennsylvania Mitral valve system
EP2749254B1 (fr) 2003-12-23 2015-06-17 Sadra Medical, Inc. Valvule cardiaque repositionnable
US9101338B2 (en) 2006-05-03 2015-08-11 Mayo Foundation For Medical Education And Research Soft body tissue remodeling methods and apparatus
EP1734903B1 (fr) 2004-03-11 2015-10-21 Percutaneous Cardiovascular Solutions Pty Limited Prothese de valvule cardiaque percutanee
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US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US10206774B2 (en) 2003-12-23 2019-02-19 Boston Scientific Scimed Inc. Low profile heart valve and delivery system
US10258465B2 (en) 2003-12-23 2019-04-16 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10278805B2 (en) 2000-08-18 2019-05-07 Atritech, Inc. Expandable implant devices for filtering blood flow from atrial appendages
US10299922B2 (en) 2005-12-22 2019-05-28 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US10314695B2 (en) 2003-12-23 2019-06-11 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10335273B2 (en) 2003-12-23 2019-07-02 Boston Scientific Scimed Inc. Leaflet engagement elements and methods for use thereof
US10413409B2 (en) 2003-12-23 2019-09-17 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10426608B2 (en) 2003-12-23 2019-10-01 Boston Scientific Scimed, Inc. Repositionable heart valve
US10531952B2 (en) 2004-11-05 2020-01-14 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US10548734B2 (en) 2005-09-21 2020-02-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US10555809B2 (en) 2012-06-19 2020-02-11 Boston Scientific Scimed, Inc. Replacement heart valve
US10828154B2 (en) 2017-06-08 2020-11-10 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
US10898325B2 (en) 2017-08-01 2021-01-26 Boston Scientific Scimed, Inc. Medical implant locking mechanism
US10939996B2 (en) 2017-08-16 2021-03-09 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US10993805B2 (en) 2008-02-26 2021-05-04 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US11147668B2 (en) 2018-02-07 2021-10-19 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
US11185405B2 (en) 2013-08-30 2021-11-30 Jenavalve Technology, Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US11191641B2 (en) 2018-01-19 2021-12-07 Boston Scientific Scimed, Inc. Inductance mode deployment sensors for transcatheter valve system
US11229517B2 (en) 2018-05-15 2022-01-25 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11241312B2 (en) 2018-12-10 2022-02-08 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
US11241310B2 (en) 2018-06-13 2022-02-08 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
US11246625B2 (en) 2018-01-19 2022-02-15 Boston Scientific Scimed, Inc. Medical device delivery system with feedback loop
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US11337800B2 (en) 2015-05-01 2022-05-24 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US11357624B2 (en) 2007-04-13 2022-06-14 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US11439732B2 (en) 2018-02-26 2022-09-13 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading
US11517431B2 (en) 2005-01-20 2022-12-06 Jenavalve Technology, Inc. Catheter system for implantation of prosthetic heart valves
US11564794B2 (en) 2008-02-26 2023-01-31 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11589981B2 (en) 2010-05-25 2023-02-28 Jenavalve Technology, Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
US11759317B2 (en) 2016-12-20 2023-09-19 Edwards Lifesciences Corporation Three-dimensional woven fabric implant devices
US11771544B2 (en) 2011-05-05 2023-10-03 Symetis Sa Method and apparatus for compressing/loading stent-valves

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US10278805B2 (en) 2000-08-18 2019-05-07 Atritech, Inc. Expandable implant devices for filtering blood flow from atrial appendages
US7621948B2 (en) 2003-07-21 2009-11-24 The Trustees Of The University Of Pennsylvania Percutaneous heart valve
US8118866B2 (en) 2003-07-21 2012-02-21 The Trustees Of The University Of Pennsylvania Method for heart valve implantation
EP2749254B2 (fr) † 2003-12-23 2019-11-06 Boston Scientific Scimed, Inc. Valvule cardiaque repositionnable
EP2749254B1 (fr) 2003-12-23 2015-06-17 Sadra Medical, Inc. Valvule cardiaque repositionnable
US10426608B2 (en) 2003-12-23 2019-10-01 Boston Scientific Scimed, Inc. Repositionable heart valve
US10413409B2 (en) 2003-12-23 2019-09-17 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US10335273B2 (en) 2003-12-23 2019-07-02 Boston Scientific Scimed Inc. Leaflet engagement elements and methods for use thereof
EP3020365B1 (fr) 2003-12-23 2016-11-30 Boston Scientific Scimed, Inc. Valvule cardiaque repositionnable
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10314695B2 (en) 2003-12-23 2019-06-11 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US11185408B2 (en) 2003-12-23 2021-11-30 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10258465B2 (en) 2003-12-23 2019-04-16 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10206774B2 (en) 2003-12-23 2019-02-19 Boston Scientific Scimed Inc. Low profile heart valve and delivery system
US11974918B2 (en) 2004-03-11 2024-05-07 Percutaneous Cardiovascular Solutions Pty Ltd Percutaneous heart valve prosthesis
US10085835B2 (en) 2004-03-11 2018-10-02 Percutaneous Cardiovascular Solutions Pty Ltd Percutaneous heart valve prosthesis
US10993806B2 (en) 2004-03-11 2021-05-04 Percutaneous Cardiovascular Solutions Pty Ltd Percutaneous heart valve prosthesis
US11213390B2 (en) 2004-03-11 2022-01-04 Percutaneous Cardiovascular Solutions Pty Ltd Method of implanting a heart valve prosthesis
US11622856B2 (en) 2004-03-11 2023-04-11 Percutaneous Cardiovascular Solutions Pty Ltd Percutaneous heart valve prosthesis
US10213298B2 (en) 2004-03-11 2019-02-26 Percutaneous Cardiovascular Solutions Pty Ltd Percutaneous heart valve prosthesis
US11744705B2 (en) 2004-03-11 2023-09-05 Percutaneous Cardiovascular Solutions Pty Ltd Method of implanting a heart valve prosthesis
EP2308425B2 (fr) † 2004-03-11 2023-10-18 Percutaneous Cardiovascular Solutions Pty Limited Prothese de valvule cardiaque percutanee
EP1734903B2 (fr) † 2004-03-11 2022-01-19 Percutaneous Cardiovascular Solutions Pty Limited Prothese de valvule cardiaque percutanee
EP1734903B1 (fr) 2004-03-11 2015-10-21 Percutaneous Cardiovascular Solutions Pty Limited Prothese de valvule cardiaque percutanee
US10531952B2 (en) 2004-11-05 2020-01-14 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US11517431B2 (en) 2005-01-20 2022-12-06 Jenavalve Technology, Inc. Catheter system for implantation of prosthetic heart valves
US9492277B2 (en) 2005-08-30 2016-11-15 Mayo Foundation For Medical Education And Research Soft body tissue remodeling methods and apparatus
US10548734B2 (en) 2005-09-21 2020-02-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US10314701B2 (en) 2005-12-22 2019-06-11 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US10299922B2 (en) 2005-12-22 2019-05-28 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US9101338B2 (en) 2006-05-03 2015-08-11 Mayo Foundation For Medical Education And Research Soft body tissue remodeling methods and apparatus
US8070802B2 (en) 2007-02-23 2011-12-06 The Trustees Of The University Of Pennsylvania Mitral valve system
US7753949B2 (en) 2007-02-23 2010-07-13 The Trustees Of The University Of Pennsylvania Valve prosthesis systems and methods
US11357624B2 (en) 2007-04-13 2022-06-14 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US11564794B2 (en) 2008-02-26 2023-01-31 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11154398B2 (en) 2008-02-26 2021-10-26 JenaValve Technology. Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US10993805B2 (en) 2008-02-26 2021-05-04 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US10856858B2 (en) 2008-11-21 2020-12-08 Percutaneous Cardiovascular Solutions Pty Ltd Heart valve prosthesis and method
US10842476B2 (en) 2008-11-21 2020-11-24 Percutaneous Cardiovascular Solutions Pty Ltd Heart valve prosthesis and method
US10166014B2 (en) 2008-11-21 2019-01-01 Percutaneous Cardiovascular Solutions Pty Ltd Heart valve prosthesis and method
US11589981B2 (en) 2010-05-25 2023-02-28 Jenavalve Technology, Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
US10869760B2 (en) 2010-09-10 2020-12-22 Symetis Sa Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device
US10201418B2 (en) 2010-09-10 2019-02-12 Symetis, SA Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device
US11771544B2 (en) 2011-05-05 2023-10-03 Symetis Sa Method and apparatus for compressing/loading stent-valves
US11382739B2 (en) 2012-06-19 2022-07-12 Boston Scientific Scimed, Inc. Replacement heart valve
US10555809B2 (en) 2012-06-19 2020-02-11 Boston Scientific Scimed, Inc. Replacement heart valve
US11185405B2 (en) 2013-08-30 2021-11-30 Jenavalve Technology, Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US10154904B2 (en) 2014-04-28 2018-12-18 Edwards Lifesciences Corporation Intravascular introducer devices
US11998448B2 (en) 2014-04-28 2024-06-04 Edwards Lifesciences Corporation Intravascular introducer devices
US11103345B2 (en) 2014-05-12 2021-08-31 Edwards Lifesciences Corporation Prosthetic heart valve
US10195025B2 (en) 2014-05-12 2019-02-05 Edwards Lifesciences Corporation Prosthetic heart valve
US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US11337800B2 (en) 2015-05-01 2022-05-24 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US11051937B2 (en) 2015-07-14 2021-07-06 Edwards Lifesciences Corporation Prosthetic heart valve
US9974650B2 (en) 2015-07-14 2018-05-22 Edwards Lifesciences Corporation Prosthetic heart valve
US10722354B2 (en) 2016-02-12 2020-07-28 Edwards Lifesciences Corporation Prosthetic heart valve having multi-level sealing member
US11744700B2 (en) 2016-02-12 2023-09-05 Edwards Lifesciences Corporation Prosthetic heart valve having multi-level sealing member
US10179043B2 (en) 2016-02-12 2019-01-15 Edwards Lifesciences Corporation Prosthetic heart valve having multi-level sealing member
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US10709552B2 (en) 2016-05-16 2020-07-14 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US11759317B2 (en) 2016-12-20 2023-09-19 Edwards Lifesciences Corporation Three-dimensional woven fabric implant devices
US10828154B2 (en) 2017-06-08 2020-11-10 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
US10898325B2 (en) 2017-08-01 2021-01-26 Boston Scientific Scimed, Inc. Medical implant locking mechanism
US10939996B2 (en) 2017-08-16 2021-03-09 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11191641B2 (en) 2018-01-19 2021-12-07 Boston Scientific Scimed, Inc. Inductance mode deployment sensors for transcatheter valve system
US11246625B2 (en) 2018-01-19 2022-02-15 Boston Scientific Scimed, Inc. Medical device delivery system with feedback loop
US11147668B2 (en) 2018-02-07 2021-10-19 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
US11439732B2 (en) 2018-02-26 2022-09-13 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
US11229517B2 (en) 2018-05-15 2022-01-25 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11241310B2 (en) 2018-06-13 2022-02-08 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
US11241312B2 (en) 2018-12-10 2022-02-08 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading

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