WO2003087843A3 - Diagnostics and therapeutics for diseases associated with mas related gene f (mrgf) - Google Patents

Diagnostics and therapeutics for diseases associated with mas related gene f (mrgf) Download PDF

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Publication number
WO2003087843A3
WO2003087843A3 PCT/EP2003/003425 EP0303425W WO03087843A3 WO 2003087843 A3 WO2003087843 A3 WO 2003087843A3 EP 0303425 W EP0303425 W EP 0303425W WO 03087843 A3 WO03087843 A3 WO 03087843A3
Authority
WO
WIPO (PCT)
Prior art keywords
diseases
mrgf
disorders
therapeutics
diagnostics
Prior art date
Application number
PCT/EP2003/003425
Other languages
French (fr)
Other versions
WO2003087843A2 (en
Inventor
Stefan Golz
Ulf Brueggemeier
Holger Summer
Original Assignee
Bayer Healthcare Ag
Stefan Golz
Ulf Brueggemeier
Holger Summer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag, Stefan Golz, Ulf Brueggemeier, Holger Summer filed Critical Bayer Healthcare Ag
Priority to AU2003229593A priority Critical patent/AU2003229593A1/en
Publication of WO2003087843A2 publication Critical patent/WO2003087843A2/en
Publication of WO2003087843A3 publication Critical patent/WO2003087843A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides a human MrgF which is associated with the cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD, asthma, genito-urological disorders, cancer, gastro-intestinal diseases, and liver diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD, asthma, genito-urological disorders, cancer, gastro-intestinal diseases, and liver diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of MrgF as well as pharmaceutical compositions comprising such compounds.
PCT/EP2003/003425 2002-04-15 2003-04-02 Diagnostics and therapeutics for diseases associated with mas related gene f (mrgf) WO2003087843A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003229593A AU2003229593A1 (en) 2002-04-15 2003-04-02 Diagnostics and therapeutics for diseases associated with mas related gene f (mrgf)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02008160 2002-04-15
EP02008160.0 2002-04-15

Publications (2)

Publication Number Publication Date
WO2003087843A2 WO2003087843A2 (en) 2003-10-23
WO2003087843A3 true WO2003087843A3 (en) 2004-09-02

Family

ID=29225583

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/003425 WO2003087843A2 (en) 2002-04-15 2003-04-02 Diagnostics and therapeutics for diseases associated with mas related gene f (mrgf)

Country Status (2)

Country Link
AU (1) AU2003229593A1 (en)
WO (1) WO2003087843A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996016087A1 (en) * 1994-11-18 1996-05-30 Human Genome Sciences, Inc. G-protein coupled receptor
WO2003004528A1 (en) * 2001-07-02 2003-01-16 Ingenium Pharmaceuticals Ag Human g protein-coupled receptors and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996016087A1 (en) * 1994-11-18 1996-05-30 Human Genome Sciences, Inc. G-protein coupled receptor
WO2003004528A1 (en) * 2001-07-02 2003-01-16 Ingenium Pharmaceuticals Ag Human g protein-coupled receptors and uses thereof

Also Published As

Publication number Publication date
WO2003087843A2 (en) 2003-10-23
AU2003229593A1 (en) 2003-10-27
AU2003229593A8 (en) 2003-10-27

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