WO2003087331A3 - Recepteur detectant les cations polyvalents dans du saumon atlantique - Google Patents

Recepteur detectant les cations polyvalents dans du saumon atlantique Download PDF

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Publication number
WO2003087331A3
WO2003087331A3 PCT/US2003/011188 US0311188W WO03087331A3 WO 2003087331 A3 WO2003087331 A3 WO 2003087331A3 US 0311188 W US0311188 W US 0311188W WO 03087331 A3 WO03087331 A3 WO 03087331A3
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WO
WIPO (PCT)
Prior art keywords
salmokcar
polyvalent cation
atlantic salmon
nucleic acid
present
Prior art date
Application number
PCT/US2003/011188
Other languages
English (en)
Other versions
WO2003087331A2 (fr
Inventor
Jr. H. William Harris
Jacqueline Nearing
Marlies Betka
Original Assignee
Marical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/125,778 external-priority patent/US6979558B2/en
Priority claimed from US10/125,792 external-priority patent/US6979559B2/en
Priority claimed from US10/125,772 external-priority patent/US6951739B2/en
Application filed by Marical, Inc. filed Critical Marical, Inc.
Priority to AU2003232002A priority Critical patent/AU2003232002A1/en
Priority to EP03746726.3A priority patent/EP1572938A4/fr
Priority to CA2481827A priority patent/CA2481827C/fr
Publication of WO2003087331A2 publication Critical patent/WO2003087331A2/fr
Publication of WO2003087331A3 publication Critical patent/WO2003087331A3/fr

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/40Fish
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne quatre séquences d'acides nucléiques et d'aminoacides pleine longueur destinées à des récepteurs détectant les cations polyvalents (PVCR) dans le saumon atlantique. Ces PVCR ont été nommés SalmoKCaR n°1, SalmoKCaR n°2, SalmoKCaR n°3, et SalmoKCaR n°4. L'invention concerne des homologues de ceux-ci, des anticorps dirigés contre ceux-ci, et des procédés permettant d'évaluer des molécules d'acides nucléiques et des polypeptides des récepteurs SalmoKCaR. L'invention concerne en outre des plasmides, des vecteurs, et des cellules hôtes contenant les séquences d'acides nucléiques des récepteurs SalmoKCaR n°1, 2, 3 et/ou 4.
PCT/US2003/011188 2000-10-12 2003-04-09 Recepteur detectant les cations polyvalents dans du saumon atlantique WO2003087331A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2003232002A AU2003232002A1 (en) 2002-04-11 2003-04-09 Polyvalent cation-sensing receptor in atlantic salmon
EP03746726.3A EP1572938A4 (fr) 2002-04-11 2003-04-09 Recepteur detectant les cations polyvalents dans du saumon atlantique
CA2481827A CA2481827C (fr) 2002-04-11 2003-04-09 Recepteur detectant les cations polyvalents dans du saumon atlantique

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US24039200P 2000-10-12 2000-10-12
US24000300P 2000-10-12 2000-10-12
US12144102A 2002-04-11 2002-04-11
US10/121,441 2002-04-11
US10/125,778 US6979558B2 (en) 2000-10-12 2002-04-18 Polyvalent cation-sensing receptor in Atlantic salmon
US10/125,772 2002-04-18
US10/125,792 US6979559B2 (en) 2000-10-12 2002-04-18 Polyvalent cation-sensing receptor in atlantic salmon
US10/125,792 2002-04-18
US10/125,778 2002-04-18
US10/125,772 US6951739B2 (en) 2000-10-12 2002-04-18 Polyvalent cation-sensing receptor in atlantic salmon

Publications (2)

Publication Number Publication Date
WO2003087331A2 WO2003087331A2 (fr) 2003-10-23
WO2003087331A3 true WO2003087331A3 (fr) 2014-07-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/011188 WO2003087331A2 (fr) 2000-10-12 2003-04-09 Recepteur detectant les cations polyvalents dans du saumon atlantique

Country Status (1)

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WO (1) WO2003087331A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2890859B1 (fr) * 2005-09-21 2012-12-21 Oreal Oligonucleotide d'arn double brin inhibant l'expression de la tyrosinase
PL3197290T3 (pl) * 2014-09-23 2019-08-30 Europharma As Pasza dla ryb i jej zastosowanie w profilaktyce i leczeniu zespołu krwotocznego smoltów (hss) u łososiowatych

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545808A (en) * 1991-03-15 1996-08-13 Hsc Research And Development Limited Partnership Transgenic salmonid fish expressing exogenous salmonid growth hormone
US6337391B1 (en) * 1996-03-27 2002-01-08 Brighams & Women's Hospital Polycation-sensing receptor in aquatic species and methods of use
WO2002031149A2 (fr) * 2000-10-12 2002-04-18 Marical, Inc. Proteines d'un recepteur sensible aux cations polyvalents presentes chez certaines especes aquatiques

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545808A (en) * 1991-03-15 1996-08-13 Hsc Research And Development Limited Partnership Transgenic salmonid fish expressing exogenous salmonid growth hormone
US6337391B1 (en) * 1996-03-27 2002-01-08 Brighams & Women's Hospital Polycation-sensing receptor in aquatic species and methods of use
WO2002031149A2 (fr) * 2000-10-12 2002-04-18 Marical, Inc. Proteines d'un recepteur sensible aux cations polyvalents presentes chez certaines especes aquatiques

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CLARK, M.S.: "Calcitonin: characterisation and expression in a teleost fish, Fugu rubripes.", JOURNAL OF MOLECULAR ENDOCRINOLOGY., vol. 28, no. 2, April 2002 (2002-04-01), pages 111 - 123, XP002972676 *
LO, Y. H. ET AL.: "High-affinity Ca2+, Mg2+-ATPase in plasma membrane-rich preparations from olfactory epithelium of Atlantic salmon.", BIOCHIMICA ET BIOPHYSICIA ACTA., vol. 1192, no. 2, 1994, pages 153 - 158, XP023354346 *
NEARING, J. ET AL.: "Polyvalent cation receptor proteins (CaRs) are salinity sensors in fish.", PNAS., vol. 99, no. 14, 9 July 2002 (2002-07-09), pages 9231 - 9236, XP002207947 *
RADMAN, D.P. ET AL.: "Evidence for calcium-sensing receptormediated stanniocalcin secretioninfish.", MOLECULAR AND CELLULAR ENDOCRINOLOGY., vol. 186, no. 1, 15 January 2002 (2002-01-15), pages 111 - 119, XP002972677 *
See also references of EP1572938A4 *

Also Published As

Publication number Publication date
WO2003087331A2 (fr) 2003-10-23

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