WO2000020590A3 - Proteines de recepteurs couples a des proteines g - Google Patents

Proteines de recepteurs couples a des proteines g Download PDF

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Publication number
WO2000020590A3
WO2000020590A3 PCT/US1999/023317 US9923317W WO0020590A3 WO 2000020590 A3 WO2000020590 A3 WO 2000020590A3 US 9923317 W US9923317 W US 9923317W WO 0020590 A3 WO0020590 A3 WO 0020590A3
Authority
WO
WIPO (PCT)
Prior art keywords
coupled receptor
protein coupled
receptor proteins
gcrp
provides
Prior art date
Application number
PCT/US1999/023317
Other languages
English (en)
Other versions
WO2000020590A2 (fr
Inventor
Y Tom Tang
Henry Yue
Preeti Lal
Olga Bandman
Janice Au-Young
Roopa Reddy
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Yalda Azimzai
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Henry Yue
Preeti Lal
Olga Bandman
Au Young Janice
Roopa Reddy
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Yalda Azimzai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Henry Yue, Preeti Lal, Olga Bandman, Au Young Janice, Roopa Reddy, Neil C Corley, Karl J Guegler, Gina A Gorgone, Mariah R Baughn, Yalda Azimzai filed Critical Incyte Pharma Inc
Priority to AU64179/99A priority Critical patent/AU6417999A/en
Priority to CA002345045A priority patent/CA2345045A1/fr
Priority to JP2000574685A priority patent/JP2003521870A/ja
Priority to EP99951820A priority patent/EP1119621A2/fr
Publication of WO2000020590A2 publication Critical patent/WO2000020590A2/fr
Publication of WO2000020590A3 publication Critical patent/WO2000020590A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne des protéines de récepteurs couplés à des protéines G (GCRP), et des polynucléotides identifiant et codant les GCRP. En outre, cette invention concerne des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes, et des antagonistes. L'invention concerne également des méthodes diagnostiques, thérapeutiques, ou préventives des troubles associés à l'expression des GCRP.
PCT/US1999/023317 1998-10-06 1999-10-06 Proteines de recepteurs couples a des proteines g WO2000020590A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU64179/99A AU6417999A (en) 1998-10-06 1999-10-06 G-protein coupled receptor proteins
CA002345045A CA2345045A1 (fr) 1998-10-06 1999-10-06 Proteines de recepteurs couples a des proteines g
JP2000574685A JP2003521870A (ja) 1998-10-06 1999-10-06 Ｇタンパク質共役受容体タンパク質
EP99951820A EP1119621A2 (fr) 1998-10-06 1999-10-06 Proteines de recepteurs couples a des proteines g

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17221198A 1998-10-06 1998-10-06
US16721998A 1998-10-06 1998-10-06
US60/172,211 1998-10-06
US13358599P 1999-05-11 1999-05-11
US60/133,585 1999-05-11

Publications (2)

Publication Number Publication Date
WO2000020590A2 WO2000020590A2 (fr) 2000-04-13
WO2000020590A3 true WO2000020590A3 (fr) 2000-07-20

Family

ID=56289949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/023317 WO2000020590A2 (fr) 1998-10-06 1999-10-06 Proteines de recepteurs couples a des proteines g

Country Status (1)

Country Link
WO (1) WO2000020590A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2162000A (en) * 1998-12-10 2000-06-26 Zymogenetics Inc. Seven transmembrane domain receptor zsig56
US6790631B1 (en) 1999-10-05 2004-09-14 Agensys, Inc. G protein-coupled receptor up-regulated in prostate cancer and uses thereof
US7208280B2 (en) 1999-10-05 2007-04-24 Agensys, Inc. Nucleic acid and corresponding protein entitled 101P3A41 useful in treatment and detection of cancer
US7361338B2 (en) 1999-10-05 2008-04-22 Agensys, Inc. Methods to inhibit growth of prostate cancer cells
ES2371212T3 (es) * 1999-10-05 2011-12-28 Agensys, Inc. Receptor acoplado a proteína g regulado positivamente en el cáncer de próstata y usos del mismo.
US20030212255A1 (en) * 2000-07-26 2003-11-13 Muralidhara Padigaru Novel proteins and nucleic acids encoding same
CA2430993A1 (fr) * 2000-12-08 2002-06-13 Incyte Genomics, Inc. Recepteurs couples a la proteine g
IL158860A0 (en) * 2001-05-15 2004-05-12 Agensys Inc Nucleic acids and corresponding proteins entitled 101p3a11 or phor-1 useful in treatment and detection of cancer and pharmaceutical compositions containing the same
CA2469480A1 (fr) * 2001-12-27 2003-07-17 Agy Therapeutics, Inc. Utilisation de cibles biomoleculaires dans le traitement et la visualisation de tumeurs
DE10225443A1 (de) * 2002-06-08 2003-12-18 Aventis Pharma Gmbh Verfahren zur Identifizierung von Agonisten oder Antagonisten für den G-Protein gekoppelten Rezeptor mas like 1
WO2004046315A2 (fr) * 2002-11-14 2004-06-03 Slowave, Inc. Compositions et procedes utilisant le recepteur de ghb humain
EP1687687A1 (fr) 2003-11-20 2006-08-09 Koninklijke Philips Electronics N.V. Procede et dispositif de mise a disposition de donnees numeriques codees

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996018651A1 (fr) * 1994-12-16 1996-06-20 Smithkline Beecham Corporation Recepteur humain somatostatinoide
EP0805204A2 (fr) * 1996-04-29 1997-11-05 Institut für Hormon- und Fortpflanzungsforschung GmbH Protéine récepteur spécifique de l'épididyme et son utilisation
WO1999015551A1 (fr) * 1997-09-24 1999-04-01 Garvan Institute Of Medical Research Nouveau recepteur
WO1999046281A2 (fr) * 1998-03-10 1999-09-16 Genentech, Inc. Nouveaux polypeptides et acides nucleiques les codant

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996018651A1 (fr) * 1994-12-16 1996-06-20 Smithkline Beecham Corporation Recepteur humain somatostatinoide
EP0805204A2 (fr) * 1996-04-29 1997-11-05 Institut für Hormon- und Fortpflanzungsforschung GmbH Protéine récepteur spécifique de l'épididyme et son utilisation
WO1999015551A1 (fr) * 1997-09-24 1999-04-01 Garvan Institute Of Medical Research Nouveau recepteur
WO1999046281A2 (fr) * 1998-03-10 1999-09-16 Genentech, Inc. Nouveaux polypeptides et acides nucleiques les codant

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMEST30 E.M.B.L. Databases; 4 October 1996 (1996-10-04), FUJIWARA T ET AL: "Human placenta cDNA 5'-end GEN-553A03", XP002130338 *
STADEL J M ET AL: "Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery", TRENDS IN PHARMACOLOGICAL SCIENCES,GB,ELSEVIER TRENDS JOURNAL, CAMBRIDGE, vol. 18, no. 11, November 1997 (1997-11-01), pages 430-437, XP004096215, ISSN: 0165-6147 *

Also Published As

Publication number Publication date
WO2000020590A2 (fr) 2000-04-13

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