WO2003074696A1 - Method of detecting base substitution - Google Patents

Method of detecting base substitution Download PDF

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Publication number
WO2003074696A1
WO2003074696A1 PCT/JP2003/002419 JP0302419W WO03074696A1 WO 2003074696 A1 WO2003074696 A1 WO 2003074696A1 JP 0302419 W JP0302419 W JP 0302419W WO 03074696 A1 WO03074696 A1 WO 03074696A1
Authority
WO
WIPO (PCT)
Prior art keywords
base substitution
detecting base
detecting
gene
chimeric oligonucleotide
Prior art date
Application number
PCT/JP2003/002419
Other languages
French (fr)
Japanese (ja)
Inventor
Junko Yamamoto
Hiroyuki Mukai
Kiyozo Asada
Ikunoshin Kato
Original Assignee
Takara Bio Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Bio Inc. filed Critical Takara Bio Inc.
Priority to JP2003573147A priority Critical patent/JP4022522B2/en
Priority to AU2003211421A priority patent/AU2003211421A1/en
Publication of WO2003074696A1 publication Critical patent/WO2003074696A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A chimeric oligonucleotide primer and a probe useful in detecting a base substitution on a gene; a method of detecting a base substitution on a gene with the use of the chimeric oligonucleotide; and a kit therefor.
PCT/JP2003/002419 2002-03-07 2003-03-03 Method of detecting base substitution WO2003074696A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2003573147A JP4022522B2 (en) 2002-03-07 2003-03-03 Detection method of base substitution
AU2003211421A AU2003211421A1 (en) 2002-03-07 2003-03-03 Method of detecting base substitution

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002/62543 2002-03-07
JP2002062543 2002-03-07

Publications (1)

Publication Number Publication Date
WO2003074696A1 true WO2003074696A1 (en) 2003-09-12

Family

ID=27784896

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2003/002419 WO2003074696A1 (en) 2002-03-07 2003-03-03 Method of detecting base substitution

Country Status (4)

Country Link
JP (1) JP4022522B2 (en)
AU (1) AU2003211421A1 (en)
TW (1) TW200401036A (en)
WO (1) WO2003074696A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010026933A1 (en) 2008-09-03 2010-03-11 タカラバイオ株式会社 Composition for detection of rna
JP5711234B2 (en) * 2010-07-29 2015-04-30 タカラバイオ株式会社 Method for producing RNA-containing probe for target base detection

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660988A (en) * 1993-11-17 1997-08-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
EP1167524A1 (en) * 1999-03-19 2002-01-02 Takara Shuzo Co, Ltd. Method for amplifying nucleic acid sequence
WO2002016639A1 (en) * 2000-08-23 2002-02-28 Takara Bio Inc. Method of amplifying nucleic acid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660988A (en) * 1993-11-17 1997-08-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
EP1167524A1 (en) * 1999-03-19 2002-01-02 Takara Shuzo Co, Ltd. Method for amplifying nucleic acid sequence
WO2002016639A1 (en) * 2000-08-23 2002-02-28 Takara Bio Inc. Method of amplifying nucleic acid

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EIJI KOBAYASHI ET AL.: "Atarashi single nucleotide polymorphisms (SNPs) typing hoho", JAPANESE JOURNAL OF SCIENCE AND TECHNOLOGY FOR IDENTIFICATION, vol. 6, no. SEPARATE VOLUME, pages 73, XP002952464 *
HSU L.C. ET AL.: "Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2", PROC. NATL. ACAD. SCI. USA, vol. 82, no. 11, 1985, pages 3771 - 3775, XP002968816 *
NISHI M. ET AL.: "Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization and evolutionary history", MOL. ENDOCRINOL., vol. 3, no. 11, 1989, pages 1775 - 1781, XP009004693 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010026933A1 (en) 2008-09-03 2010-03-11 タカラバイオ株式会社 Composition for detection of rna
US10760074B2 (en) 2008-09-03 2020-09-01 Takara Bio Inc. Composition for detection of RNA
JP5711234B2 (en) * 2010-07-29 2015-04-30 タカラバイオ株式会社 Method for producing RNA-containing probe for target base detection

Also Published As

Publication number Publication date
AU2003211421A1 (en) 2003-09-16
JPWO2003074696A1 (en) 2005-06-30
TW200401036A (en) 2004-01-16
JP4022522B2 (en) 2007-12-19

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