WO2003070229A3 - Use of proteinase inhibitors in the treatment of autoimmune diseases - Google Patents
Use of proteinase inhibitors in the treatment of autoimmune diseases Download PDFInfo
- Publication number
- WO2003070229A3 WO2003070229A3 PCT/EP2003/001807 EP0301807W WO03070229A3 WO 2003070229 A3 WO2003070229 A3 WO 2003070229A3 EP 0301807 W EP0301807 W EP 0301807W WO 03070229 A3 WO03070229 A3 WO 03070229A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treatment
- autoimmune diseases
- proteinase inhibitors
- activation
- diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003206945A AU2003206945A1 (en) | 2002-02-22 | 2003-02-21 | Use of proteinase inhibitors in the treatment of autoimmune diseases |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10207744.4 | 2002-02-22 | ||
DE10207744 | 2002-02-22 | ||
DE10241411A DE10241411A1 (en) | 2002-02-22 | 2002-09-06 | Use of proteinase inhibitors for the treatment of autoimmune diseases |
DE10241411.4 | 2002-09-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003070229A2 WO2003070229A2 (en) | 2003-08-28 |
WO2003070229A3 true WO2003070229A3 (en) | 2004-03-04 |
Family
ID=27758411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/001807 WO2003070229A2 (en) | 2002-02-22 | 2003-02-21 | Use of proteinase inhibitors in the treatment of autoimmune diseases |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003206945A1 (en) |
WO (1) | WO2003070229A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE50310038D1 (en) | 2002-03-11 | 2008-08-07 | Curacyte Ag | INGREDIENTS OF UROKINASE, THEIR PREPARATION AND USE |
DE10301300B4 (en) * | 2003-01-15 | 2009-07-16 | Curacyte Chemistry Gmbh | Use of acylated 4-amidino- and 4-guanidinobenzylamines for the inhibition of plasma kallikrein |
DE10322191B4 (en) * | 2003-05-16 | 2014-02-27 | The Medicines Company (Leipzig) Gmbh | N-sulfonylated amino acid derivatives, process for their preparation and their use |
DE10342108A1 (en) | 2003-09-11 | 2005-04-14 | Curacyte Chemistry Gmbh | Basic substituted benzylamine analogs as coagulation factor Xa inhibitors, their preparation and use |
AU2006286752B2 (en) * | 2005-08-29 | 2011-10-06 | Wilex Ag | Oxadiazole compounds as urokinase inhibitors |
DE102006050672A1 (en) | 2006-10-24 | 2008-04-30 | Curacyte Discovery Gmbh | New glycylglycine derivatives with a benzylsulfonylamido group and an amidino-organylamido group at the opposite chain ends, used in drugs for reducing loss of blood, e.g. in operations |
WO2010054307A1 (en) * | 2008-11-07 | 2010-05-14 | The Cleveland Clinic Foundation | Compounds and methods of promoting oligodendrocyte precursor differentiation |
WO2012004678A2 (en) * | 2010-07-07 | 2012-01-12 | The Medicines Company (Leipzig) Gmbh | Serine protease inhibitors |
DE102011108346A1 (en) * | 2011-07-25 | 2013-01-31 | Philipps-Universität Marburg | Use of inhibitors of TMPRSS2 as a drug |
US11130780B2 (en) | 2015-03-09 | 2021-09-28 | Washington University | Inhibitors of growth factor activation enzymes |
RU2020107706A (en) * | 2017-07-21 | 2021-08-23 | Редхилл Байофарма Лтд. | APPLICATION OF WX-UK1 AND ITS PRODUCT WX-671 FOR TREATMENT OF NON-MALIGNANT MEDICAL CONDITIONS |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998013061A1 (en) * | 1996-09-24 | 1998-04-02 | Cv Therapeutics, Inc. | Inhibition of 26s and 20s proteasome by indanones |
US5843905A (en) * | 1993-06-04 | 1998-12-01 | Vertex Pharmaceuticals, Incorporated | Peptidic phosphinyloxymethyl ketones as interleukin-1β-converting enzyme inhibitors |
US5932567A (en) * | 1995-02-10 | 1999-08-03 | Basf Aktiengesellschaft | Thrombin inhibitors |
WO2000061608A2 (en) * | 1999-04-09 | 2000-10-19 | Basf Aktiengesellschaft | Low-molecular inhibitors of complement proteases |
US6358928B1 (en) * | 1999-11-22 | 2002-03-19 | Enzyme Systems Products | Peptidyl sulfonyl imidazolides as selective inhibitors of serine proteases |
WO2002053516A2 (en) * | 2001-01-08 | 2002-07-11 | Laboratoires Fournier Sa | N(phenylsulphonyl)glycine derivatives and their therapeutic use |
WO2003037892A1 (en) * | 2001-10-29 | 2003-05-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as reversible inhibitors of cysteine proteases |
-
2003
- 2003-02-21 AU AU2003206945A patent/AU2003206945A1/en not_active Abandoned
- 2003-02-21 WO PCT/EP2003/001807 patent/WO2003070229A2/en not_active Application Discontinuation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5843905A (en) * | 1993-06-04 | 1998-12-01 | Vertex Pharmaceuticals, Incorporated | Peptidic phosphinyloxymethyl ketones as interleukin-1β-converting enzyme inhibitors |
US5932567A (en) * | 1995-02-10 | 1999-08-03 | Basf Aktiengesellschaft | Thrombin inhibitors |
WO1998013061A1 (en) * | 1996-09-24 | 1998-04-02 | Cv Therapeutics, Inc. | Inhibition of 26s and 20s proteasome by indanones |
WO2000061608A2 (en) * | 1999-04-09 | 2000-10-19 | Basf Aktiengesellschaft | Low-molecular inhibitors of complement proteases |
US6358928B1 (en) * | 1999-11-22 | 2002-03-19 | Enzyme Systems Products | Peptidyl sulfonyl imidazolides as selective inhibitors of serine proteases |
WO2002053516A2 (en) * | 2001-01-08 | 2002-07-11 | Laboratoires Fournier Sa | N(phenylsulphonyl)glycine derivatives and their therapeutic use |
WO2003037892A1 (en) * | 2001-10-29 | 2003-05-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as reversible inhibitors of cysteine proteases |
Non-Patent Citations (1)
Title |
---|
KUNGL AJ ET AL: "Time-Resolved Fluorescence Anisotropy of HIV-1 Protease Inhibitor Complexes Correlates with Inhibitory Activity", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON, PA, US, vol. 37, 13 February 1998 (1998-02-13), pages 2778 - 2786, XP002191310, ISSN: 0006-2960 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003206945A1 (en) | 2003-09-09 |
WO2003070229A2 (en) | 2003-08-28 |
AU2003206945A8 (en) | 2003-09-09 |
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