WO2003069345A3 - Analyse von proteinexpressionsmuster - Google Patents

Analyse von proteinexpressionsmuster Download PDF

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Publication number
WO2003069345A3
WO2003069345A3 PCT/EP2003/001374 EP0301374W WO03069345A3 WO 2003069345 A3 WO2003069345 A3 WO 2003069345A3 EP 0301374 W EP0301374 W EP 0301374W WO 03069345 A3 WO03069345 A3 WO 03069345A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis
protein expression
expression pattern
metabolisation
biomacromolecule
Prior art date
Application number
PCT/EP2003/001374
Other languages
English (en)
French (fr)
Other versions
WO2003069345A2 (de
Inventor
Juergen Wilhelm Rich Bernhardt
Felix Oliver Heinrich
Karin Engelhart-Jentzsch
Original Assignee
Biotesys Gmbh
Juergen Wilhelm Rich Bernhardt
Felix Oliver Heinrich
Karin Engelhart-Jentzsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotesys Gmbh, Juergen Wilhelm Rich Bernhardt, Felix Oliver Heinrich, Karin Engelhart-Jentzsch filed Critical Biotesys Gmbh
Priority to AU2003226975A priority Critical patent/AU2003226975A1/en
Publication of WO2003069345A2 publication Critical patent/WO2003069345A2/de
Publication of WO2003069345A3 publication Critical patent/WO2003069345A3/de

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zum Nachweis eines Metabolisierungsprozesses durch Immobilisierung zumindest eines Liganden mit einer spezifischen Bindungsstelle für zumindest ein Biomakromolekül auf einem Träger. Zumindest eine indikative Komponente des Biomakromoleküls eines zellulären Repertoires des Metabolisierungsprozesses in zumindest annähernd nativer und/oder metabolisierter Konformation wird durch die Interaktion der spezifischen Bindungsstelle mit einem aktiven Bindungszentrum der indikativen Komponente identifiziert.
PCT/EP2003/001374 2002-02-12 2003-02-12 Analyse von proteinexpressionsmuster WO2003069345A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003226975A AU2003226975A1 (en) 2002-02-12 2003-02-12 Analysis of a protein expression pattern

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA220/2002 2002-02-12
AT2202002 2002-02-12

Publications (2)

Publication Number Publication Date
WO2003069345A2 WO2003069345A2 (de) 2003-08-21
WO2003069345A3 true WO2003069345A3 (de) 2004-06-03

Family

ID=27671429

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/001374 WO2003069345A2 (de) 2002-02-12 2003-02-12 Analyse von proteinexpressionsmuster

Country Status (2)

Country Link
AU (1) AU2003226975A1 (de)
WO (1) WO2003069345A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106919998B (zh) * 2015-12-28 2021-07-06 航天信息股份有限公司 一种基于aoe网络的物流模型及方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000063701A2 (en) * 1999-04-15 2000-10-26 The Board Of Trustees Of The Leland Stanford Junior University Microarrays of polypeptides
WO2001077668A2 (en) * 2000-04-10 2001-10-18 The Scripps Research Institute Proteomic analysis using active-site directed probes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000063701A2 (en) * 1999-04-15 2000-10-26 The Board Of Trustees Of The Leland Stanford Junior University Microarrays of polypeptides
WO2001077668A2 (en) * 2000-04-10 2001-10-18 The Scripps Research Institute Proteomic analysis using active-site directed probes

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DE CRESCENZO G ET AL: "Real-time kinetic studies on the interaction of transforming growth factor alpha with the epidermal growth factor receptor extracellular domain reveal a conformational change model.", BIOCHEMISTRY. UNITED STATES 8 AUG 2000, vol. 39, no. 31, 8 August 2000 (2000-08-08), pages 9466 - 9476, XP002257922, ISSN: 0006-2960 *
GE HUI: "UPA, a universal protein array system for quantitative detection of protein-protein, protein-DNA, protein-RNA and protein-ligand interactions", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 28, no. 2, 2000, pages E3 - e3, XP002183744, ISSN: 0305-1048 *
MACBEATH G ET AL: "Printing proteins as microarrays for high-throughput function determination", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 289, 8 September 2000 (2000-09-08), pages 1760 - 1763, XP002190973, ISSN: 0036-8075 *
MYSZKA D G ET AL: "Implementing surface plasmon resonance biosensors in drug discovery", PHARMACEUTICAL SCIENCE AND TECHNOLOGY TODAY 01 SEP 2000 UNITED KINGDOM, vol. 3, no. 9, 1 September 2000 (2000-09-01), pages 310 - 317, XP001155380, ISSN: 1461-5347 *
OHLSON S S ET AL: "Continuous weak-affinity immunosensing", TRENDS IN BIOTECHNOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 18, no. 2, February 2000 (2000-02-01), pages 49 - 52, XP004187249, ISSN: 0167-7799 *
RICH R L ET AL: "Survey of the year 2000 commercial optical biosensor literature.", JOURNAL OF MOLECULAR RECOGNITION: JMR. ENGLAND 2001 SEP-OCT, vol. 14, no. 5, September 2001 (2001-09-01), pages 273 - 294, XP009019158, ISSN: 0952-3499 *
SLEPAK V Z: "APPLICATION OF SURFACE PLASMON RESONANCE FOR ANALYSIS OF PROTEIN-PROTEIN INTERACTIONS IN THE G PROTEIN-MEDIATED SIGNAL TRANSDUCTION PATHWAY", JOURNAL OF MOLECULAR RECOGNITION, HEYDEN & SON LTD., LONDON, GB, vol. 13, no. 1, January 2000 (2000-01-01), pages 20 - 26, XP002906134, ISSN: 0952-3499 *
STOLL D ET AL: "PROTEIN MICROARRAY TECHNOLOGY", FRONTIERS IN BIOSCIENCE, XX, XX, vol. 7, 1 January 2002 (2002-01-01), pages C13 - C32, XP008016809 *
WEINBERGER S R ET AL: "RECENT TRENDS IN PROTEIN BIOCHIP TECHNOLOGY", PHARMACOGENOMICS, ASHLEY PUBLICATIONS, GB, vol. 1, no. 3, November 2000 (2000-11-01), pages 395 - 416, XP009009627, ISSN: 1462-2416 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106919998B (zh) * 2015-12-28 2021-07-06 航天信息股份有限公司 一种基于aoe网络的物流模型及方法

Also Published As

Publication number Publication date
WO2003069345A2 (de) 2003-08-21
AU2003226975A1 (en) 2003-09-04

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