WO2003064587A3 - Hif-1 alpha proteins mutated in the c-terminal transactivation domain - Google Patents
Hif-1 alpha proteins mutated in the c-terminal transactivation domain Download PDFInfo
- Publication number
- WO2003064587A3 WO2003064587A3 PCT/SE2003/000030 SE0300030W WO03064587A3 WO 2003064587 A3 WO2003064587 A3 WO 2003064587A3 SE 0300030 W SE0300030 W SE 0300030W WO 03064587 A3 WO03064587 A3 WO 03064587A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hif
- alpha
- transactivation
- transactivation domain
- terminal transactivation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003201798A AU2003201798A1 (en) | 2002-01-11 | 2003-01-13 | Hif-1 alpha proteins mutated in the c-terminal transactivation domain |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34697602P | 2002-01-11 | 2002-01-11 | |
US60/346,976 | 2002-01-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003064587A2 WO2003064587A2 (en) | 2003-08-07 |
WO2003064587A3 true WO2003064587A3 (en) | 2003-11-13 |
Family
ID=27662960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE2003/000030 WO2003064587A2 (en) | 2002-01-11 | 2003-01-13 | Hif-1 alpha proteins mutated in the c-terminal transactivation domain |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003201798A1 (en) |
WO (1) | WO2003064587A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106366173A (en) * | 2015-07-24 | 2017-02-01 | 北京京爱康科技有限公司 | Chromatin peptide for controlling expression of anoxic reaction gene through combining hypoxic response element |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000029437A1 (en) * | 1998-11-13 | 2000-05-25 | Pharmacia Ab | HYPOXIA-INDUCIBLE FACTOR 1α HIF-1α VARIANTS AND METHODS FOR IDENTIFYING HIF-1α MODULATORS |
WO2000074725A1 (en) * | 1999-06-04 | 2000-12-14 | Dana-Farber Cancer Institute, Inc. | Identification of compounds that modify transcriptional responses to hypoxia |
-
2003
- 2003-01-13 AU AU2003201798A patent/AU2003201798A1/en not_active Abandoned
- 2003-01-13 WO PCT/SE2003/000030 patent/WO2003064587A2/en not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000029437A1 (en) * | 1998-11-13 | 2000-05-25 | Pharmacia Ab | HYPOXIA-INDUCIBLE FACTOR 1α HIF-1α VARIANTS AND METHODS FOR IDENTIFYING HIF-1α MODULATORS |
WO2000074725A1 (en) * | 1999-06-04 | 2000-12-14 | Dana-Farber Cancer Institute, Inc. | Identification of compounds that modify transcriptional responses to hypoxia |
Non-Patent Citations (4)
Title |
---|
JIE GU ET AL.: "Molecular mechanism of hypoxia-inducible factor 1alpha-p300 interaction", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 5, 2001, pages 3550 - 3554 * |
JORGE L. ET AL.: "Functional analysis of hypoxia-inducible factor-1alpha-mediated transactivation", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 41, October 2002 (2002-10-01), pages 38723 - 38730, XP055016537, DOI: doi:10.1074/jbc.M205051200 * |
O'ROURKE JOHN F. ET AL.: "Oxygen-regulated and transactivating domains in endothelial PAS protein 1: Comparison with hypoxia-inducible factor-1alpha", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 4, 1999, pages 2060 - 2071, XP002304818, DOI: doi:10.1074/jbc.274.4.2060 * |
PILAR CARRERO ET AL.: "Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha", MOLECULAR AND CELLULAR BIOLOGY, vol. 20, no. 1, 2000, pages 402 - 415 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003201798A1 (en) | 2003-09-02 |
WO2003064587A2 (en) | 2003-08-07 |
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