WO2003061684A3 - Tumour treatment compositions comprising hsp70 and tumour necrosis factor - Google Patents
Tumour treatment compositions comprising hsp70 and tumour necrosis factor Download PDFInfo
- Publication number
- WO2003061684A3 WO2003061684A3 PCT/EP2003/000786 EP0300786W WO03061684A3 WO 2003061684 A3 WO2003061684 A3 WO 2003061684A3 EP 0300786 W EP0300786 W EP 0300786W WO 03061684 A3 WO03061684 A3 WO 03061684A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tumour
- hsp70
- necrosis factor
- treatment compositions
- tumour necrosis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003218639A AU2003218639A1 (en) | 2002-01-24 | 2003-01-24 | Tumour treatment compositions comprising hsp70 and tumour necrosis factor |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02075297 | 2002-01-24 | ||
EP02075297.8 | 2002-01-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003061684A2 WO2003061684A2 (en) | 2003-07-31 |
WO2003061684A3 true WO2003061684A3 (en) | 2004-01-15 |
Family
ID=27589134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/000786 WO2003061684A2 (en) | 2002-01-24 | 2003-01-24 | Tumour treatment compositions comprising hsp70 and tumour necrosis factor |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003218639A1 (en) |
WO (1) | WO2003061684A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008523055A (en) * | 2004-12-10 | 2008-07-03 | ゼルニケ ビジネス サポート ビー.ヴィー. | Heat shock protein (HSP) and supraventricular arrhythmia |
ES2532083T3 (en) * | 2008-06-26 | 2015-03-24 | Orphazyme Aps | Use of Hsp70 as a regulator of enzymatic activity |
CN103338784A (en) | 2010-11-30 | 2013-10-02 | 奥菲泽米有限公司 | Methods for increasing intracellular activity of Hsp70 |
JP6678676B2 (en) | 2014-09-15 | 2020-04-08 | オーファザイム エー/エス | Arimoclomol formulation |
EP3442530A1 (en) | 2016-04-13 | 2019-02-20 | Orphazyme A/S | Heat shock proteins and cholesterol homeostasis |
WO2017186919A1 (en) | 2016-04-29 | 2017-11-02 | Orphazyme Aps | Arimoclomol for treating glucocerebrosidase associated disorders |
IL303026A (en) | 2020-11-19 | 2023-07-01 | Zevra Denmark As | Processes for preparing arimoclomol citrate and intermediates thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5961979A (en) * | 1994-03-16 | 1999-10-05 | Mount Sinai School Of Medicine Of The City University Of New York | Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens |
-
2003
- 2003-01-24 AU AU2003218639A patent/AU2003218639A1/en not_active Abandoned
- 2003-01-24 WO PCT/EP2003/000786 patent/WO2003061684A2/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5961979A (en) * | 1994-03-16 | 1999-10-05 | Mount Sinai School Of Medicine Of The City University Of New York | Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens |
Non-Patent Citations (3)
Title |
---|
JAATTELA, MARJA ET AL: "Heat-shock proteins protect cells from monocyte cytotoxicity: Possible mechanism of self-protection", J. EXP. MED. (1993), 177(1), 231-6, XP002943877 * |
JAATTELA, MARJA: "Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells", INT. J. CANCER (1995), 60(5), 689-93, XP008004374 * |
KIM, YOUNG-MYEONG ET AL: "Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor -.alpha.-induced apoptosis by inducing heat shock protein 70 expression", J. BIOL. CHEM. (1997), 272(2), 1402-1411, XP001077875 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003218639A1 (en) | 2003-09-02 |
WO2003061684A2 (en) | 2003-07-31 |
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