WO2003063763A3 - Essais a mediation par complement pour des procedes in vivo et in vitro - Google Patents

Essais a mediation par complement pour des procedes in vivo et in vitro Download PDF

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Publication number
WO2003063763A3
WO2003063763A3 PCT/US2002/016302 US0216302W WO03063763A3 WO 2003063763 A3 WO2003063763 A3 WO 2003063763A3 US 0216302 W US0216302 W US 0216302W WO 03063763 A3 WO03063763 A3 WO 03063763A3
Authority
WO
WIPO (PCT)
Prior art keywords
vivo
complement mediated
vitro methods
mediated assays
complement
Prior art date
Application number
PCT/US2002/016302
Other languages
English (en)
Other versions
WO2003063763A2 (fr
Inventor
Elliot R Ramberg
Original Assignee
Cygene Inc
Elliot R Ramberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygene Inc, Elliot R Ramberg filed Critical Cygene Inc
Priority to EP02806678A priority Critical patent/EP1506314A4/fr
Priority to JP2003563459A priority patent/JP2005516198A/ja
Priority to AU2002365902A priority patent/AU2002365902A1/en
Priority to CA002447892A priority patent/CA2447892A1/fr
Publication of WO2003063763A2 publication Critical patent/WO2003063763A2/fr
Publication of WO2003063763A3 publication Critical patent/WO2003063763A3/fr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/18Erythrocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des procédés et des compositions conçus pour détecter des substances cibles à analyser, telles que des protéines et des acides nucléiques, dans de multiples compartiments cellulaires. Des modes de réalisation préférés concernent la mise en oeuvre d'essais à médiation par complément et de traitements à médiation par complément chez l'être humain et l'animal. La présente invention concerne également des procédés et des compositions conçus pour surveiller plusieurs stades de maladie et d'infection.
PCT/US2002/016302 2001-05-22 2002-05-22 Essais a mediation par complement pour des procedes in vivo et in vitro WO2003063763A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP02806678A EP1506314A4 (fr) 2001-05-22 2002-05-22 Essais a mediation par complement pour des procedes in vivo et in vitro
JP2003563459A JP2005516198A (ja) 2001-05-22 2002-05-22 invivoおよびinvitroでの方法に関する補体媒介性アッセイ
AU2002365902A AU2002365902A1 (en) 2001-05-22 2002-05-22 Complement mediated assays for in vivo and in vitro methods
CA002447892A CA2447892A1 (fr) 2001-05-22 2002-05-22 Essais a mediation par complement pour des procedes in vivo et in vitro

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US29261601P 2001-05-22 2001-05-22
US60/292,616 2001-05-22
US29732101P 2001-06-11 2001-06-11
US60/297,321 2001-06-11
US32402901P 2001-09-21 2001-09-21
US60/324,029 2001-09-21

Publications (2)

Publication Number Publication Date
WO2003063763A2 WO2003063763A2 (fr) 2003-08-07
WO2003063763A3 true WO2003063763A3 (fr) 2004-12-09

Family

ID=27670579

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/016302 WO2003063763A2 (fr) 2001-05-22 2002-05-22 Essais a mediation par complement pour des procedes in vivo et in vitro

Country Status (5)

Country Link
EP (1) EP1506314A4 (fr)
JP (1) JP2005516198A (fr)
AU (1) AU2002365902A1 (fr)
CA (1) CA2447892A1 (fr)
WO (1) WO2003063763A2 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001056456A2 (fr) * 2000-02-02 2001-08-09 Cygene, Inc. Procedes et compositions permettant de detecter une maladie

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JUHL ET AL: "A monoclonal antibody-cobra venom factor conjugate increases the tumor-specific uptake of a 99mTC-labeled anti-carcinoembryonic antigen antibody by a two-step approach", CANCER RESEARCH, vol. 55, no. SUPPL., December 1995 (1995-12-01), pages 5749S - 5755S, XP000872898 *
See also references of EP1506314A4 *

Also Published As

Publication number Publication date
WO2003063763A2 (fr) 2003-08-07
EP1506314A4 (fr) 2005-08-24
AU2002365902A1 (en) 2003-09-02
EP1506314A2 (fr) 2005-02-16
JP2005516198A (ja) 2005-06-02
CA2447892A1 (fr) 2003-08-07

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