WO2003059391A3 - Viscoelastics for ocular surgery - Google Patents

Viscoelastics for ocular surgery Download PDF

Info

Publication number
WO2003059391A3
WO2003059391A3 PCT/US2002/041247 US0241247W WO03059391A3 WO 2003059391 A3 WO2003059391 A3 WO 2003059391A3 US 0241247 W US0241247 W US 0241247W WO 03059391 A3 WO03059391 A3 WO 03059391A3
Authority
WO
WIPO (PCT)
Prior art keywords
viscoelastics
ocular surgery
viscosurgery
unintentional
aspiration
Prior art date
Application number
PCT/US2002/041247
Other languages
French (fr)
Other versions
WO2003059391A2 (en
Inventor
Mandar V Shah
Original Assignee
Alcon Inc
Mandar V Shah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc, Mandar V Shah filed Critical Alcon Inc
Priority to AU2002360752A priority Critical patent/AU2002360752A1/en
Priority to US10/380,135 priority patent/US20040118414A1/en
Publication of WO2003059391A2 publication Critical patent/WO2003059391A2/en
Publication of WO2003059391A3 publication Critical patent/WO2003059391A3/en
Priority to US10/882,923 priority patent/US7363928B2/en
Priority to US11/294,247 priority patent/US7578809B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Disclosed are surface modified viscoelastics and methods of performing viscosurgery using polymer-containing irrigating solution to reduce cohesiveness of the viscoelastic agent at the interface, thereby improving its performance by reducing the occurrence of unintentional aspiration, especially in ocular surgery.
PCT/US2002/041247 2001-12-21 2002-12-20 Viscoelastics for ocular surgery WO2003059391A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2002360752A AU2002360752A1 (en) 2001-12-21 2002-12-20 Viscoelastics for ocular surgery
US10/380,135 US20040118414A1 (en) 2002-12-20 2002-12-20 Surface modified viscoelastics for ocular surgery
US10/882,923 US7363928B2 (en) 2001-12-21 2004-06-30 Dilution resistant viscoelastic compositions
US11/294,247 US7578809B2 (en) 2001-12-21 2005-12-05 Surface modified viscoelastics for ocular surgery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34291601P 2001-12-21 2001-12-21
US60/342,916 2001-12-21

Related Child Applications (4)

Application Number Title Priority Date Filing Date
US10/380,135 A-371-Of-International US20040118414A1 (en) 2001-12-21 2002-12-20 Surface modified viscoelastics for ocular surgery
US10380135 A-371-Of-International 2002-12-20
US10/882,923 Continuation-In-Part US7363928B2 (en) 2001-12-21 2004-06-30 Dilution resistant viscoelastic compositions
US11/294,247 Division US7578809B2 (en) 2001-12-21 2005-12-05 Surface modified viscoelastics for ocular surgery

Publications (2)

Publication Number Publication Date
WO2003059391A2 WO2003059391A2 (en) 2003-07-24
WO2003059391A3 true WO2003059391A3 (en) 2004-02-19

Family

ID=23343837

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/041247 WO2003059391A2 (en) 2001-12-21 2002-12-20 Viscoelastics for ocular surgery

Country Status (2)

Country Link
AU (1) AU2002360752A1 (en)
WO (1) WO2003059391A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI336257B (en) 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7914803B2 (en) 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
CA2839928C (en) 2003-06-13 2016-10-04 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
US20050215515A1 (en) * 2004-03-29 2005-09-29 Claudio Bucolo Viscoelastic composition, method of use and package
FR2878444B1 (en) * 2004-11-30 2008-04-25 Corneal Ind Soc Par Actions Si VISCOELASTIC SOLUTIONS COMPRISING SODIUM HYALURONATE AND HYDROXYPROPYLMETHYLCELLULOSE, PREPARATION AND USES
WO2007008206A1 (en) * 2005-07-11 2007-01-18 Alcon, Inc. Dilution resistant viscoelastic compositions
US20070059276A1 (en) * 2005-09-07 2007-03-15 Amo Regional Holdings Bi-modal hyaluronate
TWI635877B (en) 2015-12-18 2018-09-21 財團法人工業技術研究院 A membrane for protecting intraocular tissues and the protection methods used thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0136782A2 (en) * 1983-08-09 1985-04-10 Nestle S.A. Chondroitin sulfate/sodium hyaluronate compositions
US5409904A (en) * 1984-11-13 1995-04-25 Alcon Laboratories, Inc. Hyaluronic acid compositions and methods
JP2002255829A (en) * 2000-12-26 2002-09-11 Ophtecs Corp Collyrium solution composition and method for washing eye

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0136782A2 (en) * 1983-08-09 1985-04-10 Nestle S.A. Chondroitin sulfate/sodium hyaluronate compositions
US5409904A (en) * 1984-11-13 1995-04-25 Alcon Laboratories, Inc. Hyaluronic acid compositions and methods
JP2002255829A (en) * 2000-12-26 2002-09-11 Ophtecs Corp Collyrium solution composition and method for washing eye

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ARSHINOFF S A: "The ultimate soft-shell technique", OPHTHALMIC PRACTICE 2000 CANADA, vol. 18, no. 6, 2000, pages 289 - 290, XP009009472, ISSN: 0832-9869 *
ARSHINOFF S: "Using the dispersive-cohesive viscoelastic soft-shell technique with different ophthalmic viscosurgical devices", OPHTHALMIC PRACTICE 2000 CANADA, vol. 18, no. 5, 2000, pages 224 - 226, XP009009473, ISSN: 0832-9869 *
DATABASE WPI Section PQ Week 200273, Derwent World Patents Index; Class P33, AN 2002-679066, XP002238665 *
HOLZER M P ET AL: "Effect of Healon5 and 4 other viscoelastic substances on intraocular pressure and endothelium after cataract surgery.", JOURNAL OF CATARACT AND REFRACTIVE SURGERY. UNITED STATES FEB 2001, vol. 27, no. 2, February 2001 (2001-02-01), pages 213 - 218, XP002238664, ISSN: 0886-3350 *
RAINER G ET AL: "Intraocular pressure rise after small incision cataract surgery: a randomised intraindividual comparison of two dispersive viscoelastic agents.", THE BRITISH JOURNAL OF OPHTHALMOLOGY. ENGLAND FEB 2001, vol. 85, no. 2, February 2001 (2001-02-01), pages 139 - 142, XP002238663, ISSN: 0007-1161 *

Also Published As

Publication number Publication date
AU2002360752A1 (en) 2003-07-30
WO2003059391A2 (en) 2003-07-24

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