WO2003059375A1 - Therapie complexe pour la regeneration des tissus - Google Patents
Therapie complexe pour la regeneration des tissus Download PDFInfo
- Publication number
- WO2003059375A1 WO2003059375A1 PCT/JP2002/000297 JP0200297W WO03059375A1 WO 2003059375 A1 WO2003059375 A1 WO 2003059375A1 JP 0200297 W JP0200297 W JP 0200297W WO 03059375 A1 WO03059375 A1 WO 03059375A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cytophysiologically
- active substance
- cells
- tissue regeneration
- organ
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2002/000297 WO2003059375A1 (fr) | 2002-01-17 | 2002-01-17 | Therapie complexe pour la regeneration des tissus |
AU2002226683A AU2002226683A1 (en) | 2002-01-17 | 2002-01-17 | Complex therapy for tissue regeneration |
JP2003559536A JPWO2003059375A1 (ja) | 2002-01-17 | 2002-01-17 | 組織再生複合療法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2002/000297 WO2003059375A1 (fr) | 2002-01-17 | 2002-01-17 | Therapie complexe pour la regeneration des tissus |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003059375A1 true WO2003059375A1 (fr) | 2003-07-24 |
Family
ID=11738141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/000297 WO2003059375A1 (fr) | 2002-01-17 | 2002-01-17 | Therapie complexe pour la regeneration des tissus |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPWO2003059375A1 (fr) |
AU (1) | AU2002226683A1 (fr) |
WO (1) | WO2003059375A1 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006085697A1 (fr) * | 2005-02-14 | 2006-08-17 | Japan Health Sciences Foundation | Traitement combine pour les maladies vasculaires cerebrales utilisant une association d’adrenomeduline et de cellules souches mesenchymateuses |
JP2007537752A (ja) * | 2004-05-19 | 2007-12-27 | ザ クリーブランド クリニック ファウンデーション | 治療的応用法のための遺伝的に改変された細胞 |
JP2011529946A (ja) * | 2008-08-05 | 2011-12-15 | コアセラピクス エスエルユー | 直径10〜20μmのマイクロスフェアを含む非経口組成物 |
US8513213B2 (en) | 2009-08-28 | 2013-08-20 | The Cleveland Clinic Foundation | SDF-1 delivery for treating ischemic tissue |
US8679477B2 (en) | 2007-12-14 | 2014-03-25 | The Cleveland Clinic Foundation | Use of SDF-1 to mitigate scar formation |
US9226978B2 (en) | 2002-08-22 | 2016-01-05 | The Cleveland Clinic Foundation | Method of treating ischemic disorders |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999045775A1 (fr) * | 1998-03-09 | 1999-09-16 | St. Elizabeth's Medical Center | Compositions et methodes modulant la vascularisation |
JP2001316285A (ja) * | 2000-05-01 | 2001-11-13 | Yasuhiko Tabata | 細胞と細胞増殖因子とからなる組織器官の再生のための材料 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1007631T4 (da) * | 1997-07-14 | 2009-04-27 | Osiris Therapeutics Inc | Hjertemuskelregeneration ved anvendelse af mesenkymale stamceller |
US7749215B1 (en) * | 1998-02-05 | 2010-07-06 | Biosense, Inc. | Intracardiac cell delivery and cell transplantation |
-
2002
- 2002-01-17 WO PCT/JP2002/000297 patent/WO2003059375A1/fr active Application Filing
- 2002-01-17 JP JP2003559536A patent/JPWO2003059375A1/ja active Pending
- 2002-01-17 AU AU2002226683A patent/AU2002226683A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999045775A1 (fr) * | 1998-03-09 | 1999-09-16 | St. Elizabeth's Medical Center | Compositions et methodes modulant la vascularisation |
JP2001316285A (ja) * | 2000-05-01 | 2001-11-13 | Yasuhiko Tabata | 細胞と細胞増殖因子とからなる組織器官の再生のための材料 |
Non-Patent Citations (1)
Title |
---|
DONALD ORLIC ET AL.: "Mobilized bone marrow cells repair the infarcted heart, improving function and survival", PROC. NATL. ACAD. SCI. USA, vol. 98, no. 18, August 2001 (2001-08-01), pages 10344 - 10349, XP002950780 * |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9226978B2 (en) | 2002-08-22 | 2016-01-05 | The Cleveland Clinic Foundation | Method of treating ischemic disorders |
JP2007537752A (ja) * | 2004-05-19 | 2007-12-27 | ザ クリーブランド クリニック ファウンデーション | 治療的応用法のための遺伝的に改変された細胞 |
WO2006085697A1 (fr) * | 2005-02-14 | 2006-08-17 | Japan Health Sciences Foundation | Traitement combine pour les maladies vasculaires cerebrales utilisant une association d’adrenomeduline et de cellules souches mesenchymateuses |
US8679477B2 (en) | 2007-12-14 | 2014-03-25 | The Cleveland Clinic Foundation | Use of SDF-1 to mitigate scar formation |
JP2011529946A (ja) * | 2008-08-05 | 2011-12-15 | コアセラピクス エスエルユー | 直径10〜20μmのマイクロスフェアを含む非経口組成物 |
US8513213B2 (en) | 2009-08-28 | 2013-08-20 | The Cleveland Clinic Foundation | SDF-1 delivery for treating ischemic tissue |
US8513007B2 (en) | 2009-08-28 | 2013-08-20 | The Cleveland Clinic Foundation | SDF-1 delivery for treating ischemic tissue |
US8883756B2 (en) | 2009-08-28 | 2014-11-11 | Juventas Therapeutics, Inc. | SDF-1 delivery for treating ischemic tissue |
US9844581B2 (en) | 2009-08-28 | 2017-12-19 | The Cleveland Clinic | SDF-1 delivery for treating ischemic tissue |
Also Published As
Publication number | Publication date |
---|---|
AU2002226683A1 (en) | 2003-07-30 |
JPWO2003059375A1 (ja) | 2005-05-19 |
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