WO2003057161A3 - BENZOTHIENO [3,2-c]PYRAZOLYL AND BENZOFURANO [3,2-c] PYRAZOLYL COMPOUNDS, THEIR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR AND INTERMEDIATE COMPOUNDS THEREOF - Google Patents
BENZOTHIENO [3,2-c]PYRAZOLYL AND BENZOFURANO [3,2-c] PYRAZOLYL COMPOUNDS, THEIR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR AND INTERMEDIATE COMPOUNDS THEREOF Download PDFInfo
- Publication number
- WO2003057161A3 WO2003057161A3 PCT/US2002/041859 US0241859W WO03057161A3 WO 2003057161 A3 WO2003057161 A3 WO 2003057161A3 US 0241859 W US0241859 W US 0241859W WO 03057161 A3 WO03057161 A3 WO 03057161A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pyrazolyl
- compounds
- benzofurano
- benzothieno
- diseases associated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002367323A AU2002367323A1 (en) | 2001-12-28 | 2002-12-28 | Benzothieno (3,2- |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34415101P | 2001-12-28 | 2001-12-28 | |
US60/344,151 | 2001-12-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003057161A2 WO2003057161A2 (en) | 2003-07-17 |
WO2003057161A3 true WO2003057161A3 (en) | 2011-08-04 |
Family
ID=23349272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/041859 WO2003057161A2 (en) | 2001-12-28 | 2002-12-28 | BENZOTHIENO [3,2-c]PYRAZOLYL AND BENZOFURANO [3,2-c] PYRAZOLYL COMPOUNDS, THEIR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR AND INTERMEDIATE COMPOUNDS THEREOF |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002367323A1 (en) |
WO (1) | WO2003057161A2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2004000826A1 (en) | 2003-04-25 | 2005-03-04 | Pfizer | USE OF AN AGONIST FOR THE 5-HT2C RECEPTOR TO PREPARE A USEFUL MEDICINAL PRODUCT IN THE TREATMENT OF URINARY INCONTINENCE CAUSED BY STRESS, WITH THE CONDITION THAT THE AGONIST IS NOT 1- [6-CHLORINE-5- (TRIFLUOROMETIL) -2- PIRIDINIL] PIPERAZINA (ORG-129 |
EP2305352A1 (en) | 2004-04-02 | 2011-04-06 | Merck Sharp & Dohme Corp. | 5-alpha-reductase inhibitors for use in the treatment of men with metabolic and anthropometric disorders |
EP2400300A1 (en) | 2004-08-25 | 2011-12-28 | Takeda Pharmaceutical Company Limited | Method of screening preventives/remedies for stress urinary incontinence |
CN102631349A (en) | 2004-12-23 | 2012-08-15 | 艾尼纳制药公司 | 5ht2c receptor modulator compositions and methods of use |
AU2012201515B2 (en) * | 2004-12-23 | 2015-01-29 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulator compositions and methods of use |
WO2007132841A1 (en) | 2006-05-16 | 2007-11-22 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound and use thereof |
ES2745411T3 (en) * | 2006-07-27 | 2020-03-02 | Wang Nai Fang | Arylsulfanil compounds and compositions for administration of active agents |
EP2216023A4 (en) | 2007-11-15 | 2013-03-13 | Takeda Pharmaceutical | Condensed pyridine derivative and use thereof |
JP5491421B2 (en) | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ, インコーポレイテッド | Process for the preparation of intermediates related to the 5-HT2C agonist (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
WO2010148207A2 (en) | 2009-06-18 | 2010-12-23 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
US20120253036A1 (en) | 2009-12-11 | 2012-10-04 | Yukinori Nagakura | Agent for treating fibromyalgia |
WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
SG10201506870PA (en) | 2010-09-01 | 2015-10-29 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
SG188362A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
US8999970B2 (en) | 2010-09-01 | 2015-04-07 | Arena Pharmaceuticals, Inc. | Administration of an anti-obesity compound to individuals with renal impairment |
EP2611433A2 (en) | 2010-09-01 | 2013-07-10 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
KR20150070249A (en) | 2012-10-09 | 2015-06-24 | 아레나 파마슈티칼스, 인크. | Method of weight management |
GB201304811D0 (en) * | 2013-03-15 | 2013-05-01 | Proximagen Ltd | Novel treatment for hypertension |
EP3733204A4 (en) | 2017-12-27 | 2021-09-15 | Takeda Pharmaceutical Company Limited | Therapeutic agent for stress urinary incontinence and fecal incontinence |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0700905A1 (en) * | 1994-08-12 | 1996-03-13 | F. Hoffmann-La Roche Ag | Tricyclic pyrazole derivatives |
-
2002
- 2002-12-28 WO PCT/US2002/041859 patent/WO2003057161A2/en active Search and Examination
- 2002-12-28 AU AU2002367323A patent/AU2002367323A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0700905A1 (en) * | 1994-08-12 | 1996-03-13 | F. Hoffmann-La Roche Ag | Tricyclic pyrazole derivatives |
Non-Patent Citations (2)
Title |
---|
BERTACCINI G ET AL: "THE RELATIVE POTENCY OF 5-HYDROXYTRYPTAMINE LIKE SUBSTANCES", ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE, HEYMANS INSTITUTE OF PHARMACOLOGY, GHENT, BE, vol. 133, no. 1/02, 24 January 1961 (1961-01-24), pages 138 - 156, XP000881463, ISSN: 0003-9780 * |
CHIPPENDALE, K. E. ET AL: "Condensed thiophene ring systems. XI. Synthesis of 2-aryl[1]benzothieno[3,2-c]pyrazoles and 2-aryl[1]benzothieno[2,3-c]pyrazoles", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1: ORGANIC AND BIO-ORGANIC CHEMISTRY (1972-1999) , (2), 129-33 CODEN: JCPRB4; ISSN: 0300-922X, 1973, XP002639047 * |
Also Published As
Publication number | Publication date |
---|---|
AU2002367323A1 (en) | 2003-07-24 |
AU2002367323A8 (en) | 2011-08-25 |
WO2003057161A2 (en) | 2003-07-17 |
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