WO2003048299A3 - Novel spore wall proteins and genes from microsporidia - Google Patents

Novel spore wall proteins and genes from microsporidia Download PDF

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Publication number
WO2003048299A3
WO2003048299A3 PCT/US2001/047182 US0147182W WO03048299A3 WO 2003048299 A3 WO2003048299 A3 WO 2003048299A3 US 0147182 W US0147182 W US 0147182W WO 03048299 A3 WO03048299 A3 WO 03048299A3
Authority
WO
WIPO (PCT)
Prior art keywords
microsporidia
genes
wall proteins
spore wall
proteins
Prior art date
Application number
PCT/US2001/047182
Other languages
French (fr)
Other versions
WO2003048299A2 (en
Inventor
J Russell Hayman
Theodore E Nash
Original Assignee
Us Gov Health & Human Serv
J Russell Hayman
Theodore E Nash
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, J Russell Hayman, Theodore E Nash filed Critical Us Gov Health & Human Serv
Priority to PCT/US2001/047182 priority Critical patent/WO2003048299A2/en
Priority to AU2002226011A priority patent/AU2002226011A1/en
Publication of WO2003048299A2 publication Critical patent/WO2003048299A2/en
Publication of WO2003048299A3 publication Critical patent/WO2003048299A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention provides methods of diagnosing and vaccines for preventing and treating microsporidiosis in a subject. Specifically, the present invention provides spore wall proteins of Encephalitozoon intestinalis, nucleic acids that encode the proteins and compositions for producing an immune response in a subject to microsporidia.
PCT/US2001/047182 2001-12-04 2001-12-04 Novel spore wall proteins and genes from microsporidia WO2003048299A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/US2001/047182 WO2003048299A2 (en) 2001-12-04 2001-12-04 Novel spore wall proteins and genes from microsporidia
AU2002226011A AU2002226011A1 (en) 2001-12-04 2001-12-04 Novel spore wall proteins and genes from microsporidia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/047182 WO2003048299A2 (en) 2001-12-04 2001-12-04 Novel spore wall proteins and genes from microsporidia

Publications (2)

Publication Number Publication Date
WO2003048299A2 WO2003048299A2 (en) 2003-06-12
WO2003048299A3 true WO2003048299A3 (en) 2003-10-02

Family

ID=21743089

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/047182 WO2003048299A2 (en) 2001-12-04 2001-12-04 Novel spore wall proteins and genes from microsporidia

Country Status (2)

Country Link
AU (1) AU2002226011A1 (en)
WO (1) WO2003048299A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112724223B (en) * 2020-12-28 2022-10-21 华南农业大学 Preparation and application of monoclonal antibody of spore wall protein of nosema enteromorpha
CN114732895B (en) * 2022-05-06 2023-09-29 暨南大学 Application of spore wall protein in preventing and controlling shrimp liver and intestine cytozoon infection of feeding shrimp

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOHNE W. ET AL.: "Developmental expression of a tandemly repeated, glycine- and serine-rich spore wall protein in the microsporidian pathogen encephalitozoon cuniculi", INFECTION AND IMMUNITY, vol. 68, no. 4, April 2000 (2000-04-01), pages 2268 - 2275, XP002965986 *
BOHNE W. ET AL.: "Developmental expression of two spore wall proteins during maturation of the microsporidian encephalitozoon intestinalis", INFECTION AND IMMUNITY, vol. 69, no. 11, November 2001 (2001-11-01), pages 7057 - 7066, XP002965987 *
XIAO ET AL.: "Genotyping encephalitozoon cuniculi by multilocus analyses of genes with repetative sequences", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 39, no. 6, June 2001 (2001-06-01), pages 2248 - 2253, XP002965988 *

Also Published As

Publication number Publication date
AU2002226011A8 (en) 2003-06-17
WO2003048299A2 (en) 2003-06-12
AU2002226011A1 (en) 2003-06-17

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