WO2003042148A3 - Process for producing bisbenzil compounds - Google Patents

Process for producing bisbenzil compounds Download PDF

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Publication number
WO2003042148A3
WO2003042148A3 PCT/JP2002/011682 JP0211682W WO03042148A3 WO 2003042148 A3 WO2003042148 A3 WO 2003042148A3 JP 0211682 W JP0211682 W JP 0211682W WO 03042148 A3 WO03042148 A3 WO 03042148A3
Authority
WO
WIPO (PCT)
Prior art keywords
bisbenzil
compounds
producing
compound
halide
Prior art date
Application number
PCT/JP2002/011682
Other languages
French (fr)
Other versions
WO2003042148A2 (en
Inventor
Hiroshi Yasuda
Original Assignee
Showa Denko Kk
Hiroshi Yasuda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2001346485A external-priority patent/JP2003146961A/en
Priority claimed from JP2001365438A external-priority patent/JP2003171332A/en
Priority claimed from JP2001393396A external-priority patent/JP2003192628A/en
Priority claimed from JP2001393397A external-priority patent/JP2003192629A/en
Application filed by Showa Denko Kk, Hiroshi Yasuda filed Critical Showa Denko Kk
Priority to AU2002344645A priority Critical patent/AU2002344645A1/en
Publication of WO2003042148A2 publication Critical patent/WO2003042148A2/en
Publication of WO2003042148A3 publication Critical patent/WO2003042148A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/784—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic with all keto groups bound to a non-condensed ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A bis(phenylacetyl)benzene compound is reacted with a sulfoxide compound and a halide in the presence of an acid and an organic solvent. Also, a bis((-ketonitrile) compound is reacted in an acidic environment in the presence of water, a halide and a sulfoxide compound. It is thereby possible to produce bisbenzil compounds at a high yield and with high productivity.
PCT/JP2002/011682 2001-11-12 2002-11-08 Process for producing bisbenzil compounds WO2003042148A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002344645A AU2002344645A1 (en) 2001-11-12 2002-11-08 Process for producing bisbenzil compounds

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP2001346485A JP2003146961A (en) 2001-11-12 2001-11-12 Method for producing bis(beta-ketonitrile) compound
JP2001-346485 2001-11-12
JP2001365438A JP2003171332A (en) 2001-11-30 2001-11-30 Method for producing bisbenzyl compound
JP2001-365438 2001-11-30
US33715901P 2001-12-10 2001-12-10
US60/337,159 2001-12-10
JP2001393396A JP2003192628A (en) 2001-12-26 2001-12-26 Method for producing bisbenzyl compound
JP2001-393397 2001-12-26
JP2001-393396 2001-12-26
JP2001393397A JP2003192629A (en) 2001-12-26 2001-12-26 Method for producing bis(phenylacetyl)benzene

Publications (2)

Publication Number Publication Date
WO2003042148A2 WO2003042148A2 (en) 2003-05-22
WO2003042148A3 true WO2003042148A3 (en) 2003-10-16

Family

ID=27532034

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/011682 WO2003042148A2 (en) 2001-11-12 2002-11-08 Process for producing bisbenzil compounds

Country Status (2)

Country Link
AU (1) AU2002344645A1 (en)
WO (1) WO2003042148A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103435464B (en) * 2013-09-03 2014-11-26 山东诚创医药技术开发有限公司 Preparation method of diphenylethanone

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046814A (en) * 1975-12-18 1977-09-06 Wright State University Preparation of diketones
US4082806A (en) * 1975-12-18 1978-04-04 Wright State University Preparation of tetraketones

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046814A (en) * 1975-12-18 1977-09-06 Wright State University Preparation of diketones
US4082806A (en) * 1975-12-18 1978-04-04 Wright State University Preparation of tetraketones

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 100, no. 23, 4 June 1984, Columbus, Ohio, US; abstract no. 191502, XING, LANMIN ET AL: "Study on the oxidation of bis(.alpha.-methylenecarbonyl) compounds" XP002246054 *
DULENKO V I ET AL: "Method for the synthesis of bisbenzo(c)pyrylium salts", CHEMISTRY OF HETEROCYCLIC COMPOUNDS, vol. 23, no. 5, pages 493 - 495, XP008018794 *
FILIMONOV V D ET AL: "METHODS FOR SYNTHESIS OF AROMATIC BIS-1,2-DIKETONES, BISMETHOXYSTRYRYLS, AND BISDEOXYBENZOINS FROM 1,4-DISTYRYLBENZENE", JOURNAL OF ORGANIC CHEMISTRY OF THE USSR. (ZHURNAL ORGANICHESKOI KHIMII), CONSULTANTS BUREAU. NEW YORK, US, vol. 25, no. 4, PART 2, 1 April 1989 (1989-04-01), pages 753 - 756, XP000081392 *
TONG, LING ET AL: "The Albatrossenes: Large, Cleft-Containing, Polyphenyl Polycyclic Aromatic Hydrocarbons", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (1997), 119(31), 7291-7302, XP002246053 *
YOUJI HUAXUE (1983), (6), 447-50, 425 *

Also Published As

Publication number Publication date
AU2002344645A1 (en) 2003-05-26
WO2003042148A2 (en) 2003-05-22

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