WO2003034980A8 - A novel pharmaceutical compound containing abacavir sulfate and methods of making and using same - Google Patents

A novel pharmaceutical compound containing abacavir sulfate and methods of making and using same

Info

Publication number
WO2003034980A8
WO2003034980A8 PCT/US2001/043089 US0143089W WO03034980A8 WO 2003034980 A8 WO2003034980 A8 WO 2003034980A8 US 0143089 W US0143089 W US 0143089W WO 03034980 A8 WO03034980 A8 WO 03034980A8
Authority
WO
WIPO (PCT)
Prior art keywords
making
methods
same
compound containing
pharmaceutical compound
Prior art date
Application number
PCT/US2001/043089
Other languages
French (fr)
Other versions
WO2003034980A2 (en
Inventor
Thomas Picariello
Original Assignee
New River Pharmaceuticals Inc
Thomas Picariello
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT01274606T priority Critical patent/ATE462412T1/en
Application filed by New River Pharmaceuticals Inc, Thomas Picariello filed Critical New River Pharmaceuticals Inc
Priority to DE60141719T priority patent/DE60141719D1/en
Priority to AU2001298033A priority patent/AU2001298033B2/en
Priority to CA002428971A priority patent/CA2428971A1/en
Priority to JP2003537549A priority patent/JP2006516948A/en
Priority to IL15590501A priority patent/IL155905A0/en
Priority to EP01274606A priority patent/EP1401374B1/en
Publication of WO2003034980A2 publication Critical patent/WO2003034980A2/en
Priority to IL155905A priority patent/IL155905A/en
Priority to US10/923,088 priority patent/US7427600B2/en
Publication of WO2003034980A8 publication Critical patent/WO2003034980A8/en
Priority to US11/392,878 priority patent/US20070060500A1/en
Priority to IL194439A priority patent/IL194439A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PCT/US2001/043089 2000-08-22 2001-11-14 A novel pharmaceutical compound containing abacavir sulfate and methods of making and using same WO2003034980A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IL15590501A IL155905A0 (en) 2000-11-14 2001-11-14 A novel pharmaceutical composition containing abacavir sulfate and methods of making and using same
DE60141719T DE60141719D1 (en) 2000-11-14 2001-11-14 NEW PHARMACEUTICAL COMPOUND WITH ATENOLOL AND METHOD FOR THE PRODUCTION AND USE THEREOF
AU2001298033A AU2001298033B2 (en) 2000-11-14 2001-11-14 A novel pharmaceutical compound containing abacavir sulfate and methods of making and using same
CA002428971A CA2428971A1 (en) 2000-11-14 2001-11-14 Conjugates of a therapeutic agent and a peptide carrier
JP2003537549A JP2006516948A (en) 2000-11-14 2001-11-14 New drug compound containing abacavir sulfate and method for producing and using the compound
AT01274606T ATE462412T1 (en) 2000-11-14 2001-11-14 NEW PHARMACEUTICAL COMPOUND CONTAINING ATENOLOL AND METHOD FOR THE PRODUCTION AND USE THEREOF
EP01274606A EP1401374B1 (en) 2000-11-14 2001-11-14 A novel pharmaceutical compound containing atenolol and methods of making and using same
IL155905A IL155905A (en) 2000-11-14 2003-05-14 Pharmaceutical compositions containing polypeptides covalently attached to active agents and methods for making and using same
US10/923,088 US7427600B2 (en) 2000-08-22 2004-08-23 Active agent delivery systems and methods for protecting and administering active agents
US11/392,878 US20070060500A1 (en) 2000-08-22 2006-03-30 Pharmaceutical compositions for prevention of overdose or abuse
IL194439A IL194439A (en) 2000-11-14 2008-09-28 Pharmaceutical compositions containing polypeptides covalently attached to active agents and methods for making and using same

Applications Claiming Priority (310)

Application Number Priority Date Filing Date Title
US24769800P 2000-11-14 2000-11-14
US24770000P 2000-11-14 2000-11-14
US24761200P 2000-11-14 2000-11-14
US24780300P 2000-11-14 2000-11-14
US24771700P 2000-11-14 2000-11-14
US24761600P 2000-11-14 2000-11-14
US24769900P 2000-11-14 2000-11-14
US24756000P 2000-11-14 2000-11-14
US24770200P 2000-11-14 2000-11-14
US24771600P 2000-11-14 2000-11-14
US24783300P 2000-11-14 2000-11-14
US24762700P 2000-11-14 2000-11-14
US24792600P 2000-11-14 2000-11-14
US24761000P 2000-11-14 2000-11-14
US24779900P 2000-11-14 2000-11-14
US24755600P 2000-11-14 2000-11-14
US27462200P 2000-11-14 2000-11-14
US24762500P 2000-11-14 2000-11-14
US24759400P 2000-11-14 2000-11-14
US24761400P 2000-11-14 2000-11-14
US24762100P 2000-11-14 2000-11-14
US24780400P 2000-11-14 2000-11-14
US24763100P 2000-11-14 2000-11-14
US24762000P 2000-11-14 2000-11-14
US24761700P 2000-11-14 2000-11-14
US24762800P 2000-11-14 2000-11-14
US24783200P 2000-11-14 2000-11-14
US24755800P 2000-11-14 2000-11-14
US24779800P 2000-11-14 2000-11-14
US24760700P 2000-11-14 2000-11-14
US24760900P 2000-11-14 2000-11-14
US24795400P 2000-11-14 2000-11-14
US24779700P 2000-11-14 2000-11-14
US24762600P 2000-11-14 2000-11-14
US24780700P 2000-11-14 2000-11-14
US24780200P 2000-11-14 2000-11-14
US24763500P 2000-11-14 2000-11-14
US24771900P 2000-11-14 2000-11-14
US24759500P 2000-11-14 2000-11-14
US24792700P 2000-11-14 2000-11-14
US24756100P 2000-11-14 2000-11-14
US24771800P 2000-11-14 2000-11-14
US24780000P 2000-11-14 2000-11-14
US24775400P 2000-11-14 2000-11-14
US24775300P 2000-11-14 2000-11-14
US24763200P 2000-11-14 2000-11-14
US24780100P 2000-11-14 2000-11-14
US24763300P 2000-11-14 2000-11-14
US24762900P 2000-11-14 2000-11-14
US24760600P 2000-11-14 2000-11-14
US24763000P 2000-11-14 2000-11-14
US24763400P 2000-11-14 2000-11-14
US24761300P 2000-11-14 2000-11-14
US24770100P 2000-11-14 2000-11-14
US24780500P 2000-11-14 2000-11-14
US24761100P 2000-11-14 2000-11-14
US24755900P 2000-11-14 2000-11-14
US24792800P 2000-11-14 2000-11-14
US24761500P 2000-11-14 2000-11-14
US24792900P 2000-11-14 2000-11-14
US24760800P 2000-11-14 2000-11-14
US24793000P 2000-11-14 2000-11-14
US60/247,752 2000-11-14
US60/247,750 2000-11-14
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US60/247,631 2000-11-14
US60/247,548 2000-11-14
US60/247,836 2000-11-14
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US60/247,885 2000-11-14
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US60/247,719 2000-11-14
US60/247,612 2000-11-14
US60/247,580 2000-11-14
US60/247,894 2000-11-14
US60/247,736 2000-11-14
US60/247,913 2000-11-14
US60/247,873 2000-11-14
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US60/247,806 2000-11-14
US60/247,910 2000-11-14
US60/247,772 2000-11-14
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US60/247,915 2000-11-14
US60/247,799 2000-11-14
US60/247,802 2000-11-14
US60/274,622 2000-11-14
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US60/247,733 2000-11-14
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US60/247,911 2000-11-14
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US60/247,898 2000-11-14
US60/247,595 2000-11-14
US60/247,833 2000-11-14
US60/247,725 2000-11-14
US60/247,685 2000-11-14
US60/247,837 2000-11-14
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US60/247,766 2000-11-14
US60/247,801 2000-11-14
US60/247,628 2000-11-14
US60/247,812 2000-11-14

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US09/933,708 Continuation-In-Part US20020099013A1 (en) 2000-08-22 2001-08-22 Active agent delivery systems and methods for protecting and administering active agents
PCT/US2001/043117 Continuation-In-Part WO2003020200A2 (en) 2000-08-22 2001-11-16 A novel pharmaceutical compound and methods of making and using same

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US98745801A Continuation-In-Part 2000-08-22 2001-11-14
US98807101A Continuation-In-Part 2000-08-22 2001-11-16
US10/156,527 Continuation-In-Part US7060708B2 (en) 1999-03-10 2002-05-29 Active agent delivery systems and methods for protecting and administering active agents

Publications (2)

Publication Number Publication Date
WO2003034980A2 WO2003034980A2 (en) 2003-05-01
WO2003034980A8 true WO2003034980A8 (en) 2005-11-03

Family

ID=29425002

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/043089 WO2003034980A2 (en) 2000-08-22 2001-11-14 A novel pharmaceutical compound containing abacavir sulfate and methods of making and using same

Country Status (1)

Country Link
WO (1) WO2003034980A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716452B1 (en) 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
CN1649614A (en) * 2002-02-22 2005-08-03 新河药品股份有限公司 Active agent delivery systems and methods for protecting and administering active agents
AU2004251647B2 (en) 2003-05-29 2010-01-14 Takeda Pharmaceutical Company Limited Abuse resistant amphetamine compounds
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
ES2702848T3 (en) 2011-02-23 2019-03-05 Coeruleus Ltd Flumazenil complexes, compositions comprising them and uses thereof

Also Published As

Publication number Publication date
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