WO2003023063A1 - Methode d'estimation du risque d'apparition de diabetes - Google Patents

Methode d'estimation du risque d'apparition de diabetes Download PDF

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Publication number
WO2003023063A1
WO2003023063A1 PCT/JP2002/009093 JP0209093W WO03023063A1 WO 2003023063 A1 WO2003023063 A1 WO 2003023063A1 JP 0209093 W JP0209093 W JP 0209093W WO 03023063 A1 WO03023063 A1 WO 03023063A1
Authority
WO
WIPO (PCT)
Prior art keywords
intron
positions
diabetes
onset risk
judging
Prior art date
Application number
PCT/JP2002/009093
Other languages
English (en)
French (fr)
Inventor
Mitsuo Itakura
Hiroaki Yasumo
Ichiro Watanabe
Original Assignee
Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company, Limited filed Critical Sankyo Company, Limited
Publication of WO2003023063A1 publication Critical patent/WO2003023063A1/ja

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PCT/JP2002/009093 2001-09-07 2002-09-06 Methode d'estimation du risque d'apparition de diabetes WO2003023063A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001271870 2001-09-07
JP2001-271870 2001-09-07
JP2002090861 2002-03-28
JP2002-90861 2002-03-28

Publications (1)

Publication Number Publication Date
WO2003023063A1 true WO2003023063A1 (fr) 2003-03-20

Family

ID=26621828

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/009093 WO2003023063A1 (fr) 2001-09-07 2002-09-06 Methode d'estimation du risque d'apparition de diabetes

Country Status (1)

Country Link
WO (1) WO2003023063A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009078385A1 (ja) 2007-12-18 2009-06-25 Japan Health Sciences Foundation 遺伝子多型を用いた２型糖尿病の検査方法
WO2015033565A1 (ja) 2013-09-06 2015-03-12 国立大学法人東京大学 癌の診断、阻害剤のスクリーニングにおけるｒｈｏａの使用
WO2015037681A1 (ja) 2013-09-11 2015-03-19 国立大学法人京都大学 抗甲状腺薬誘発性無顆粒球症リスクを判定するための検査方法及び判定用キット
WO2020105562A1 (en) * 2018-11-20 2020-05-28 Okinawa Institute Of Science And Technology School Corporation Method for evaluating risk of type 2 diabetes using blood metabolites as an index

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021330A1 (en) * 1992-04-22 1993-10-28 Zymogenetics, Inc. Human glutamine:fructose-6-phosphate amino-transferase
WO2000037617A1 (en) * 1998-12-22 2000-06-29 G.D. Searle & Co. Glutamine: fructose-6-phosphate aminotransferase ii enzyme and their encoding nucleic acids
WO2001057182A2 (en) * 2000-01-31 2001-08-09 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021330A1 (en) * 1992-04-22 1993-10-28 Zymogenetics, Inc. Human glutamine:fructose-6-phosphate amino-transferase
WO2000037617A1 (en) * 1998-12-22 2000-06-29 G.D. Searle & Co. Glutamine: fructose-6-phosphate aminotransferase ii enzyme and their encoding nucleic acids
WO2001057182A2 (en) * 2000-01-31 2001-08-09 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DEHAVEN J.E. ET AL.: "A novel variant of glutamine: fructose-6-phosphate amidotransferase-1 (GFAT1) mRNA is selectively expressed in striated muscle", DIABETES, vol. 50, no. 11, November 2001 (2001-11-01), pages 2419 - 2424, XP002959858 *
MCKNIGHT G.L. ET AL.: "Molecular cloning, cDNA sequence and bacterial expression of human glutamine: fructose-6-phosphate amidotransferase", J. BIOL. CHEM., vol. 267, no. 35, 1992, pages 25208 - 25212, XP000906785 *
NIIMI M. ET AL.: "Identification of GFAT1-L, a novel splice variant of human glutamine: fructose-6-phosphate amidotransferase (GFAT1) that is expressed abundantly in skeletal muscle", J. HUM. GENET., vol. 46, no. 10, 2001, pages 566 - 571, XP002959859 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009078385A1 (ja) 2007-12-18 2009-06-25 Japan Health Sciences Foundation 遺伝子多型を用いた２型糖尿病の検査方法
WO2015033565A1 (ja) 2013-09-06 2015-03-12 国立大学法人東京大学 癌の診断、阻害剤のスクリーニングにおけるｒｈｏａの使用
EP3591050A2 (en) 2013-09-06 2020-01-08 The University of Tokyo Use of rhoa in cancer diagnosis and inhibitor screening
EP4335920A2 (en) 2013-09-06 2024-03-13 The University of Tokyo Use of rhoa in cancer diagnosis and inhibitor screening
WO2015037681A1 (ja) 2013-09-11 2015-03-19 国立大学法人京都大学 抗甲状腺薬誘発性無顆粒球症リスクを判定するための検査方法及び判定用キット
WO2020105562A1 (en) * 2018-11-20 2020-05-28 Okinawa Institute Of Science And Technology School Corporation Method for evaluating risk of type 2 diabetes using blood metabolites as an index

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