WO2003020112A3 - System and method for screening patients for diabetic retinopathy - Google Patents

System and method for screening patients for diabetic retinopathy Download PDF

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Publication number
WO2003020112A3
WO2003020112A3 PCT/US2002/027586 US0227586W WO03020112A3 WO 2003020112 A3 WO2003020112 A3 WO 2003020112A3 US 0227586 W US0227586 W US 0227586W WO 03020112 A3 WO03020112 A3 WO 03020112A3
Authority
WO
WIPO (PCT)
Prior art keywords
diabetic retinopathy
hemorrhages
present
screening patients
nerve
Prior art date
Application number
PCT/US2002/027586
Other languages
French (fr)
Other versions
WO2003020112A9 (en
WO2003020112A2 (en
Inventor
Stephen H Sinclair
Sanjay Bhasin
Original Assignee
Philadelphia Ophthalmic Imagin
Stephen H Sinclair
Sanjay Bhasin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philadelphia Ophthalmic Imagin, Stephen H Sinclair, Sanjay Bhasin filed Critical Philadelphia Ophthalmic Imagin
Priority to CA002458815A priority Critical patent/CA2458815A1/en
Priority to AU2002327575A priority patent/AU2002327575A1/en
Priority to JP2003524431A priority patent/JP2005508215A/en
Priority to EP02763573A priority patent/EP1427338A2/en
Priority to IL16064502A priority patent/IL160645A0/en
Publication of WO2003020112A2 publication Critical patent/WO2003020112A2/en
Publication of WO2003020112A3 publication Critical patent/WO2003020112A3/en
Publication of WO2003020112A9 publication Critical patent/WO2003020112A9/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • A61B3/1241—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes specially adapted for observation of ocular blood flow, e.g. by fluorescein angiography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Eye Examination Apparatus (AREA)
  • Image Processing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention (Fig.1) comprises a robust technique to automatically grade retinal images through detection of lesions that occur early in the course of diabetic retinopathy: dot hemorrhages or microaneurysms, blot and striate hemorrhages, lipid exudates and nerve-fiber layer infarcts. In addition, the present invention includes methods to extract the optic nerve in the appropriately identified fields, and to track and identify the vessels (measuring vessel diameters, tortuosity and branching angles).
PCT/US2002/027586 2001-08-30 2002-08-30 System and method for screening patients for diabetic retinopathy WO2003020112A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002458815A CA2458815A1 (en) 2001-08-30 2002-08-30 System and method for screening patients for diabetic retinopathy
AU2002327575A AU2002327575A1 (en) 2001-08-30 2002-08-30 System and method for screening patients for diabetic retinopathy
JP2003524431A JP2005508215A (en) 2001-08-30 2002-08-30 System and method for screening patients with diabetic retinopathy
EP02763573A EP1427338A2 (en) 2001-08-30 2002-08-30 System and method for screening patients for diabetic retinopathy
IL16064502A IL160645A0 (en) 2001-08-30 2002-08-30 System and method for screening patients for diabetic retinopathy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31595301P 2001-08-30 2001-08-30
US60/315,953 2001-08-30

Publications (3)

Publication Number Publication Date
WO2003020112A2 WO2003020112A2 (en) 2003-03-13
WO2003020112A3 true WO2003020112A3 (en) 2003-10-16
WO2003020112A9 WO2003020112A9 (en) 2004-05-06

Family

ID=23226811

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/027586 WO2003020112A2 (en) 2001-08-30 2002-08-30 System and method for screening patients for diabetic retinopathy

Country Status (6)

Country Link
EP (1) EP1427338A2 (en)
JP (1) JP2005508215A (en)
AU (1) AU2002327575A1 (en)
CA (1) CA2458815A1 (en)
IL (1) IL160645A0 (en)
WO (1) WO2003020112A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10313975B4 (en) * 2002-03-28 2007-08-23 Heidelberg Engineering Gmbh Procedure for examining the fundus
JP5014593B2 (en) * 2005-06-01 2012-08-29 興和株式会社 Ophthalmic measuring device
JP4958254B2 (en) * 2005-09-30 2012-06-20 興和株式会社 Image analysis system and image analysis program
WO2008062528A1 (en) * 2006-11-24 2008-05-29 Nidek Co., Ltd. Fundus image analyzer
JP5182689B2 (en) * 2008-02-14 2013-04-17 日本電気株式会社 Fundus image analysis method, apparatus and program thereof
SG191664A1 (en) * 2008-04-08 2013-07-31 Univ Singapore Retinal image analysis systems and methods
WO2010044791A1 (en) * 2008-10-15 2010-04-22 Optibrand Ltd., Llc Method and apparatus for obtaining an image of an ocular feature
GB0902280D0 (en) * 2009-02-12 2009-03-25 Univ Aberdeen Disease determination
US20110129133A1 (en) 2009-12-02 2011-06-02 Ramos Joao Diogo De Oliveira E Methods and systems for detection of retinal changes
US9357916B2 (en) * 2012-05-10 2016-06-07 Carl Zeiss Meditec, Inc. Analysis and visualization of OCT angiography data
US9364147B2 (en) * 2013-02-11 2016-06-14 Lifelens, Llc System, method and device for automatic noninvasive screening for diabetes and pre-diabetes
TWI549649B (en) * 2013-09-24 2016-09-21 廣達電腦股份有限公司 Head mounted system
US8879813B1 (en) 2013-10-22 2014-11-04 Eyenuk, Inc. Systems and methods for automated interest region detection in retinal images
US20170100030A1 (en) * 2014-06-03 2017-04-13 Socialeyes Corporation Systems and methods for retinopathy workflow, evaluation and grading using mobile devices
US20160278983A1 (en) * 2015-03-23 2016-09-29 Novartis Ag Systems, apparatuses, and methods for the optimization of laser photocoagulation
JP6745496B2 (en) * 2016-08-19 2020-08-26 学校法人自治医科大学 Diabetic retinopathy stage determination support system and method for supporting stage determination of diabetic retinopathy
US10169872B2 (en) 2016-11-02 2019-01-01 International Business Machines Corporation Classification of severity of pathological condition using hybrid image representation
JP2021007017A (en) * 2020-09-15 2021-01-21 株式会社トプコン Medical image processing method and medical image processing device
JP2022117177A (en) 2021-01-29 2022-08-10 富士フイルム株式会社 Device, method, and program for processing information
CN117808786B (en) * 2024-01-02 2024-05-24 珠海全一科技有限公司 Retinal artery branch angle change correlation prediction method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5940802A (en) * 1997-03-17 1999-08-17 The Board Of Regents Of The University Of Oklahoma Digital disease management system
US6198532B1 (en) * 1991-02-22 2001-03-06 Applied Spectral Imaging Ltd. Spectral bio-imaging of the eye

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6198532B1 (en) * 1991-02-22 2001-03-06 Applied Spectral Imaging Ltd. Spectral bio-imaging of the eye
US5940802A (en) * 1997-03-17 1999-08-17 The Board Of Regents Of The University Of Oklahoma Digital disease management system

Also Published As

Publication number Publication date
EP1427338A2 (en) 2004-06-16
JP2005508215A (en) 2005-03-31
CA2458815A1 (en) 2003-03-13
AU2002327575A1 (en) 2003-03-18
WO2003020112A9 (en) 2004-05-06
IL160645A0 (en) 2004-07-25
WO2003020112A2 (en) 2003-03-13

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