WO2003014352A3 - Nucleic acids for aminocoumarin biosynthesis - Google Patents

Nucleic acids for aminocoumarin biosynthesis Download PDF

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Publication number
WO2003014352A3
WO2003014352A3 PCT/EP2002/008777 EP0208777W WO03014352A3 WO 2003014352 A3 WO2003014352 A3 WO 2003014352A3 EP 0208777 W EP0208777 W EP 0208777W WO 03014352 A3 WO03014352 A3 WO 03014352A3
Authority
WO
WIPO (PCT)
Prior art keywords
aminocoumarin
nucleic acids
biosynthesis
gene clusters
biosynthetic gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/008777
Other languages
French (fr)
Other versions
WO2003014352A2 (en
Inventor
Lutz Heide
Shu-Ming Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eberhard Karls Universitaet Tuebingen
Original Assignee
Eberhard Karls Universitaet Tuebingen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eberhard Karls Universitaet Tuebingen filed Critical Eberhard Karls Universitaet Tuebingen
Priority to EP02794562A priority Critical patent/EP1414968A2/en
Priority to US10/485,710 priority patent/US20050064563A1/en
Publication of WO2003014352A2 publication Critical patent/WO2003014352A2/en
Publication of WO2003014352A3 publication Critical patent/WO2003014352A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to isolated nucleic acids coding for enzymes or functionally active fragments thereof encoded by aminocoumarin biosynthetic gene clusters, to novel aminocoumarin compounds as well as to a method for the production of modified aminocoumarins utilizing the genetic information contained in said aminocoumarin biosynthetic gene clusters.
PCT/EP2002/008777 2001-08-08 2002-08-06 Nucleic acids for aminocoumarin biosynthesis Ceased WO2003014352A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02794562A EP1414968A2 (en) 2001-08-08 2002-08-06 Nucleic acids for aminocoumarin biosynthesis
US10/485,710 US20050064563A1 (en) 2001-08-08 2002-08-06 Nucleic acids for aminocoumarin biosynthesis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31080801P 2001-08-08 2001-08-08
US60/310,808 2001-08-08

Publications (2)

Publication Number Publication Date
WO2003014352A2 WO2003014352A2 (en) 2003-02-20
WO2003014352A3 true WO2003014352A3 (en) 2003-12-24

Family

ID=23204199

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/008777 Ceased WO2003014352A2 (en) 2001-08-08 2002-08-06 Nucleic acids for aminocoumarin biosynthesis

Country Status (3)

Country Link
US (1) US20050064563A1 (en)
EP (1) EP1414968A2 (en)
WO (1) WO2003014352A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6788156B2 (en) * 2019-01-30 2020-11-25 Ｔｈｓ株式会社 Analog meter imaging device
AU2020364533A1 (en) * 2019-10-11 2022-04-21 National University Of Singapore Biosynthesis of cannabinoid precursors using novel aromatic prenyl transferases
US20230348518A1 (en) * 2020-10-05 2023-11-02 H. Lee Moffitt Cancer Center And Research Institute, Inc. Helicase inhibitors for treatment of medical disorders

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 8 July 2001 (2001-07-08), WANG Z ET AL: "Streptomyces rishiriensis strain DSM 40489 coumermycin A1 biosynthetic cluster, complete sequence", XP002228032, Database accession no. AF235050 *
STEFFENSKY MARION ET AL: "Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 44, no. 5, May 2000 (2000-05-01), pages 1214 - 1222, XP002228031, ISSN: 0066-4804 *
WANG, ZHAO-XIN ET AL: "Identification of the coumermycin A1 biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000), 44(11), 3040-3048, AF235050, XP002228030 *

Also Published As

Publication number Publication date
EP1414968A2 (en) 2004-05-06
US20050064563A1 (en) 2005-03-24
WO2003014352A2 (en) 2003-02-20

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