WO2003010315A1 - Abca7 splicing variant - Google Patents

Abca7 splicing variant Download PDF

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Publication number
WO2003010315A1
WO2003010315A1 PCT/JP2002/007487 JP0207487W WO03010315A1 WO 2003010315 A1 WO2003010315 A1 WO 2003010315A1 JP 0207487 W JP0207487 W JP 0207487W WO 03010315 A1 WO03010315 A1 WO 03010315A1
Authority
WO
WIPO (PCT)
Prior art keywords
abca7
splicing variant
amino acid
sjoegren
autoantigen
Prior art date
Application number
PCT/JP2002/007487
Other languages
French (fr)
Japanese (ja)
Inventor
Kazumitsu Ueda
Satoshi Nakagawa
Takahiro Nagase
Original Assignee
Kyowa Hakko Kogyo Co., Ltd.
Kazusa Dna Research Institute Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co., Ltd., Kazusa Dna Research Institute Foundation filed Critical Kyowa Hakko Kogyo Co., Ltd.
Publication of WO2003010315A1 publication Critical patent/WO2003010315A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

It is intended to provide a novel ABC transporter which participates in the immune system by clarifying the full amino acid sequence of an autoantigen SS-N of Sjoegren disease and the base sequence of its cDNA. Thus, polypeptides respectively having the amino acid sequences represented by SEQ ID NOS:3 and 6 are provided.
PCT/JP2002/007487 2001-07-25 2002-07-24 Abca7 splicing variant WO2003010315A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001224176 2001-07-25
JP2001-224176 2001-07-25
JP2001372530A JP2005021001A (en) 2001-07-25 2001-12-06 Abca7 splicing variant
JP2001-372530 2001-12-06

Publications (1)

Publication Number Publication Date
WO2003010315A1 true WO2003010315A1 (en) 2003-02-06

Family

ID=26619224

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/007487 WO2003010315A1 (en) 2001-07-25 2002-07-24 Abca7 splicing variant

Country Status (2)

Country Link
JP (1) JP2005021001A (en)
WO (1) WO2003010315A1 (en)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AROWU R. TANAKA ET AL.: "Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjogren's syndrome", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 283, no. 5, May 2001 (2001-05-01), pages 1019 - 1025, XP002957605 *
WOLFGANG E. KAMINSKI ET AL.: "Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: tandem linkage with the minor histocompatibility antigen HA-1 gene", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 278, no. 3, 2000, pages 782 - 789, XP000990417 *

Also Published As

Publication number Publication date
JP2005021001A (en) 2005-01-27

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