WO2003009885A3 - Systemes d'hemofiltration, procedes et dispositifs utilises dans le traitement de maladies liees aux mediateurs de l'inflammation - Google Patents

Systemes d'hemofiltration, procedes et dispositifs utilises dans le traitement de maladies liees aux mediateurs de l'inflammation Download PDF

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Publication number
WO2003009885A3
WO2003009885A3 PCT/US2002/023603 US0223603W WO03009885A3 WO 2003009885 A3 WO2003009885 A3 WO 2003009885A3 US 0223603 W US0223603 W US 0223603W WO 03009885 A3 WO03009885 A3 WO 03009885A3
Authority
WO
WIPO (PCT)
Prior art keywords
stream
ultrafiltrate
related disease
methods
inflammatory mediator
Prior art date
Application number
PCT/US2002/023603
Other languages
English (en)
Other versions
WO2003009885A2 (fr
Inventor
James R Matson
Patrice A Lee
Original Assignee
Immunocept L L C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/912,904 external-priority patent/US6730266B2/en
Application filed by Immunocept L L C filed Critical Immunocept L L C
Priority to AU2002319690A priority Critical patent/AU2002319690A1/en
Priority to EP02750294A priority patent/EP1409041A4/fr
Publication of WO2003009885A2 publication Critical patent/WO2003009885A2/fr
Publication of WO2003009885A3 publication Critical patent/WO2003009885A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention se rapporte à un système d'hémofiltration pour mammifères. Ce système comporte un hémofiltre et un dispositif d'absorption. Cet hémofiltre enlève l'ultrafiltrat d'un flux sanguin issu d'un mammifère afin de créer un flux sanguin et un flux d'ultrafiltrat. Le dispositif d'absorption est constitué de un ou plusieurs matériaux absorbants et sert à absorber des médiateurs d'inflammation du flux d'ultrafiltrat issu de l'hémofiltre, et à ôter les médiateurs d'inflammation entraînant des maladies liées aux médiateurs de l'inflammation, des sepsis, et des SIRS/MODS/MOSF afin de créer un flux d'ultrafiltrat après l'absorption. Ce flux est combiné de manière sélective avec le flux sanguin filtré et, ensemble, ces deux flux sont renvoyés vers le mammifère.
PCT/US2002/023603 2001-07-25 2002-07-24 Systemes d'hemofiltration, procedes et dispositifs utilises dans le traitement de maladies liees aux mediateurs de l'inflammation WO2003009885A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002319690A AU2002319690A1 (en) 2001-07-25 2002-07-24 Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease
EP02750294A EP1409041A4 (fr) 2001-07-25 2002-07-24 Systemes d'hemofiltration, procedes et dispositifs utilises dans le traitement de maladies liees aux mediateurs de l'inflammation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/912,904 US6730266B2 (en) 1998-07-10 2001-07-25 Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease
US09/912,904 2001-07-25

Publications (2)

Publication Number Publication Date
WO2003009885A2 WO2003009885A2 (fr) 2003-02-06
WO2003009885A3 true WO2003009885A3 (fr) 2003-07-03

Family

ID=25432668

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/023603 WO2003009885A2 (fr) 2001-07-25 2002-07-24 Systemes d'hemofiltration, procedes et dispositifs utilises dans le traitement de maladies liees aux mediateurs de l'inflammation

Country Status (3)

Country Link
EP (1) EP1409041A4 (fr)
AU (1) AU2002319690A1 (fr)
WO (1) WO2003009885A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8038638B2 (en) 2004-02-23 2011-10-18 Hemolife Medical, Inc. Plasma detoxification and volume control system and methods of use
US8339447B2 (en) 2004-10-21 2012-12-25 Truevision Systems, Inc. Stereoscopic electronic microscope workstation
ATE477009T1 (de) * 2007-01-12 2010-08-15 Bellco Srl Kit zur behandlung von erkrankungen im zusammenhang mit systemischen entzündungen
CN102227244A (zh) 2008-10-02 2011-10-26 匹兹堡大学-属高等教育联邦体系 用于治疗全身性炎症的吸附剂聚合物的施用
US20170266362A1 (en) 2014-08-26 2017-09-21 3M Innovative Properties Company System for removal of pro-inflammatory mediators as well as granulocytes and monocytes from blood

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0098392A2 (fr) * 1982-07-02 1984-01-18 Gambro Dialysatoren GmbH & Co. KG Membrane filtrante et procédé de fabrication
US4844810A (en) * 1986-08-08 1989-07-04 Hospal Industrie Installation with multiple functions for replacement of the natural filtration of the blood
US5536412A (en) * 1992-02-06 1996-07-16 Hemocleanse, Inc. Hemofiltration and plasmafiltration devices and methods
US5571418A (en) * 1993-08-20 1996-11-05 Lee; Patrice A. Hemofiltration of toxic mediator-related disease
EP0787500A1 (fr) * 1996-02-06 1997-08-06 BELLCO S.p.A. Procede et dispositif de seperation de toxines en particulier de cytokines
US5858238A (en) * 1996-03-08 1999-01-12 Baxter Research Medical, Inc. Salvage of autologous blood via selective membrane/sorption technologies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287516B1 (en) * 1998-07-10 2001-09-11 Immunocept, L.L.C. Hemofiltration systems, methods, and devices used to treat inflammatory mediator related disease

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0098392A2 (fr) * 1982-07-02 1984-01-18 Gambro Dialysatoren GmbH & Co. KG Membrane filtrante et procédé de fabrication
US4844810A (en) * 1986-08-08 1989-07-04 Hospal Industrie Installation with multiple functions for replacement of the natural filtration of the blood
US5536412A (en) * 1992-02-06 1996-07-16 Hemocleanse, Inc. Hemofiltration and plasmafiltration devices and methods
US5571418A (en) * 1993-08-20 1996-11-05 Lee; Patrice A. Hemofiltration of toxic mediator-related disease
EP0787500A1 (fr) * 1996-02-06 1997-08-06 BELLCO S.p.A. Procede et dispositif de seperation de toxines en particulier de cytokines
US5858238A (en) * 1996-03-08 1999-01-12 Baxter Research Medical, Inc. Salvage of autologous blood via selective membrane/sorption technologies

Also Published As

Publication number Publication date
EP1409041A4 (fr) 2007-05-16
EP1409041A2 (fr) 2004-04-21
WO2003009885A2 (fr) 2003-02-06
AU2002319690A1 (en) 2003-02-17

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