WO2003004531A3 - Regulation d'une proteine du type recepteur de la somatostatine humaine - Google Patents

Regulation d'une proteine du type recepteur de la somatostatine humaine Download PDF

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Publication number
WO2003004531A3
WO2003004531A3 PCT/EP2002/007564 EP0207564W WO03004531A3 WO 2003004531 A3 WO2003004531 A3 WO 2003004531A3 EP 0207564 W EP0207564 W EP 0207564W WO 03004531 A3 WO03004531 A3 WO 03004531A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
somatostatin receptor
human somatostatin
regulation
reagents
Prior art date
Application number
PCT/EP2002/007564
Other languages
English (en)
Other versions
WO2003004531A2 (fr
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Healthcare Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag, Shyam Ramakrishnan filed Critical Bayer Healthcare Ag
Publication of WO2003004531A2 publication Critical patent/WO2003004531A2/fr
Publication of WO2003004531A3 publication Critical patent/WO2003004531A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/655—Somatostatins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des réactifs qui régulent une protéine de type récepteur de la somatostatine humaine, et des réactifs qui se lient avec les produits géniques de type récepteur de la somatostatine humaine. Ces réactifs sont utilisés pour réguler l'effet de la somatostatine, et permettent de traiter les maladies du système nerveux périphérique et central, les maladies hématologiques, l'obésité, le diabète, l'asthme et les cancers.
PCT/EP2002/007564 2001-07-06 2002-07-08 Regulation d'une proteine du type recepteur de la somatostatine humaine WO2003004531A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EPPCT/EP01/07737 2001-07-06
PCT/EP2001/007737 WO2003004530A1 (fr) 2001-07-06 2001-07-06 Régulation de la protéine semblable à un récepteur de la somatostatine humaine

Publications (2)

Publication Number Publication Date
WO2003004531A2 WO2003004531A2 (fr) 2003-01-16
WO2003004531A3 true WO2003004531A3 (fr) 2003-12-04

Family

ID=8164490

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2001/007737 WO2003004530A1 (fr) 2001-07-06 2001-07-06 Régulation de la protéine semblable à un récepteur de la somatostatine humaine
PCT/EP2002/007564 WO2003004531A2 (fr) 2001-07-06 2002-07-08 Regulation d'une proteine du type recepteur de la somatostatine humaine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007737 WO2003004530A1 (fr) 2001-07-06 2001-07-06 Régulation de la protéine semblable à un récepteur de la somatostatine humaine

Country Status (1)

Country Link
WO (2) WO2003004530A1 (fr)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037679A1 (fr) * 1998-01-26 1999-07-29 Millennium Pharmaceuticals, Inc. Recepteurs de ligands et leurs utilisations
WO2000064942A1 (fr) * 1999-04-27 2000-11-02 Smithkline Beecham Corporation Axor-27, recepteur couple a une proteine g
WO2001012673A1 (fr) * 1999-08-17 2001-02-22 Merck Patent Gmbh Polypeptides pgpcr-3 et leurs sequences d'adn
WO2001036473A2 (fr) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Recepteurs couples a une proteine g
WO2001036471A2 (fr) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Versions endogenes et non-endogenes de recepteurs couples a la proteine g humaine
WO2001042288A2 (fr) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. Recepteurs couples a la proteine g
WO2001048188A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a la proteine de liaison a guanosine triphosphate, leurs genes, leur preparation et leur utilisation
WO2001068848A2 (fr) * 2000-03-01 2001-09-20 Genentech, Inc. Polypeptides secretes et transmembranaires et acides nucleiques codant pour ces polypeptides
WO2001090189A2 (fr) * 2000-05-24 2001-11-29 Akzo Nobel N.V. Gene org3 du recepteur couple a une proteine g

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037679A1 (fr) * 1998-01-26 1999-07-29 Millennium Pharmaceuticals, Inc. Recepteurs de ligands et leurs utilisations
WO2000064942A1 (fr) * 1999-04-27 2000-11-02 Smithkline Beecham Corporation Axor-27, recepteur couple a une proteine g
WO2001012673A1 (fr) * 1999-08-17 2001-02-22 Merck Patent Gmbh Polypeptides pgpcr-3 et leurs sequences d'adn
WO2001036473A2 (fr) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Recepteurs couples a une proteine g
WO2001036471A2 (fr) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Versions endogenes et non-endogenes de recepteurs couples a la proteine g humaine
WO2001042288A2 (fr) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. Recepteurs couples a la proteine g
WO2001048188A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a la proteine de liaison a guanosine triphosphate, leurs genes, leur preparation et leur utilisation
WO2001068848A2 (fr) * 2000-03-01 2001-09-20 Genentech, Inc. Polypeptides secretes et transmembranaires et acides nucleiques codant pour ces polypeptides
WO2001090189A2 (fr) * 2000-05-24 2001-11-29 Akzo Nobel N.V. Gene org3 du recepteur couple a une proteine g

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 200145, Derwent World Patents Index; Class B04, AN 2001-425662, XP002190613 *
LEE D K ET AL: "Discovery and mapping of ten novel G protein-coupled receptor genes", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 275, no. 1, 5 September 2001 (2001-09-05), pages 83 - 91, XP004307114, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
WO2003004531A2 (fr) 2003-01-16
WO2003004530A1 (fr) 2003-01-16

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