WO2003000154A3 - Lentilles intraoculaires d'accommodation ameliorees - Google Patents

Lentilles intraoculaires d'accommodation ameliorees Download PDF

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Publication number
WO2003000154A3
WO2003000154A3 PCT/US2002/019534 US0219534W WO03000154A3 WO 2003000154 A3 WO2003000154 A3 WO 2003000154A3 US 0219534 W US0219534 W US 0219534W WO 03000154 A3 WO03000154 A3 WO 03000154A3
Authority
WO
WIPO (PCT)
Prior art keywords
eye
lens
intraocular lens
lenses
positive
Prior art date
Application number
PCT/US2002/019534
Other languages
English (en)
Other versions
WO2003000154B1 (fr
WO2003000154A2 (fr
Inventor
David Miller
Ernesto Blanco
Peter Magnante
Original Assignee
David Miller
Ernesto Blanco
Peter Magnante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by David Miller, Ernesto Blanco, Peter Magnante filed Critical David Miller
Priority to AU2002315375A priority Critical patent/AU2002315375A1/en
Priority to EP02742223A priority patent/EP1399097A4/fr
Publication of WO2003000154A2 publication Critical patent/WO2003000154A2/fr
Publication of WO2003000154A3 publication Critical patent/WO2003000154A3/fr
Priority to US10/738,271 priority patent/US20050060032A1/en
Priority to US10/964,863 priority patent/US7118597B2/en
Publication of WO2003000154B1 publication Critical patent/WO2003000154B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648—Multipart lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1616—Pseudo-accommodative, e.g. multifocal or enabling monovision
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0053—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in optical properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne des lentilles intraoculaires comportant une lentille positive et une lentille négative qui bougent lorsque l'oeil s'accommode pour rendre plus nette sur la rétine l'image d'un objet observé sur une large gamme de distances. Ces lentilles positive et négative peuvent être soit fixées mécaniquement pour restreindre leurs mouvements relatifs, soit non fixées. Après extraction de la cataracte, le chirurgien implante ces lentilles dans le sillon ciliaire ou dans la capsule du cristallin. Dans une variante, une des lentilles peut être introduite dans un oeil qui contient déjà une lentille implantée pour améliorer davantage la vision du patient.
PCT/US2002/019534 2001-06-22 2002-06-21 Lentilles intraoculaires d'accommodation ameliorees WO2003000154A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2002315375A AU2002315375A1 (en) 2001-06-22 2002-06-21 An improved accommodating intraocular lens
EP02742223A EP1399097A4 (fr) 2001-06-22 2002-06-21 Lentilles intraoculaires d'accommodation ameliorees
US10/738,271 US20050060032A1 (en) 2001-06-22 2003-12-17 Accommodating intraocular lens
US10/964,863 US7118597B2 (en) 2001-06-22 2004-10-14 Accommodating intraocular lens

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29975701P 2001-06-22 2001-06-22
US60/299,757 2001-06-22

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/738,271 Continuation-In-Part US20050060032A1 (en) 2001-06-22 2003-12-17 Accommodating intraocular lens

Publications (3)

Publication Number Publication Date
WO2003000154A2 WO2003000154A2 (fr) 2003-01-03
WO2003000154A3 true WO2003000154A3 (fr) 2003-05-22
WO2003000154B1 WO2003000154B1 (fr) 2005-07-28

Family

ID=23156157

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/019534 WO2003000154A2 (fr) 2001-06-22 2002-06-21 Lentilles intraoculaires d'accommodation ameliorees

Country Status (4)

Country Link
US (1) US20050060032A1 (fr)
EP (1) EP1399097A4 (fr)
AU (1) AU2002315375A1 (fr)
WO (1) WO2003000154A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7662179B2 (en) 1999-04-09 2010-02-16 Sarfarazi Faezeh M Haptics for accommodative intraocular lens system
US8556967B2 (en) 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector

Families Citing this family (52)

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US20060238702A1 (en) * 1999-04-30 2006-10-26 Advanced Medical Optics, Inc. Ophthalmic lens combinations
US20030060881A1 (en) * 1999-04-30 2003-03-27 Advanced Medical Optics, Inc. Intraocular lens combinations
US8062361B2 (en) * 2001-01-25 2011-11-22 Visiogen, Inc. Accommodating intraocular lens system with aberration-enhanced performance
US7150759B2 (en) * 2002-01-14 2006-12-19 Advanced Medical Optics, Inc. Multi-mechanistic accommodating intraocular lenses
US7763069B2 (en) 2002-01-14 2010-07-27 Abbott Medical Optics Inc. Accommodating intraocular lens with outer support structure
US6695881B2 (en) 2002-04-29 2004-02-24 Alcon, Inc. Accommodative intraocular lens
US7662180B2 (en) 2002-12-05 2010-02-16 Abbott Medical Optics Inc. Accommodating intraocular lens and method of manufacture thereof
US20050027354A1 (en) 2003-07-28 2005-02-03 Advanced Medical Optics, Inc. Primary and supplemental intraocular lens
US20050131535A1 (en) 2003-12-15 2005-06-16 Randall Woods Intraocular lens implant having posterior bendable optic
IL161706A0 (en) 2004-04-29 2004-09-27 Nulens Ltd Intraocular lens fixation device
WO2006103674A2 (fr) 2005-03-30 2006-10-05 Nulens Ltd Ensembles lentille intraoculaire accommodative (aiol) et composants separes pour lesdits ensembles
NL1029037C2 (nl) 2005-05-13 2006-11-14 Akkolens Int Bv Verbeterde intra-oculaire kunstlens met variable optische sterkte.
US9636213B2 (en) 2005-09-30 2017-05-02 Abbott Medical Optics Inc. Deformable intraocular lenses and lens systems
EP3338743A1 (fr) 2006-01-17 2018-06-27 Novartis Ag Dispositif de traitement pour l'administration de médicaments
WO2007138564A1 (fr) * 2006-05-31 2007-12-06 Acuity (Israel) Ltd. Kit d'adaptation de lentille multiple
US20080147185A1 (en) 2006-05-31 2008-06-19 Xin Hong Correction of chromatic aberrations in intraocular lenses
US20080097600A1 (en) * 2006-10-24 2008-04-24 Ivan Hare Movable ophthalmic lens assembly
CA2673388C (fr) 2006-12-22 2015-11-24 Amo Groningen B.V. Lentille intraoculaire d'accommodation, systeme de lentille et structure pour lentille
WO2008079671A1 (fr) 2006-12-22 2008-07-03 Bausch & Lomb Incorporated Lentille intraoculaire d'accommodation à éléments multiples
US20080161914A1 (en) 2006-12-29 2008-07-03 Advanced Medical Optics, Inc. Pre-stressed haptic for accommodating intraocular lens
USD702346S1 (en) 2007-03-05 2014-04-08 Nulens Ltd. Haptic end plate for use in an intraocular assembly
US8414646B2 (en) 2007-12-27 2013-04-09 Forsight Labs, Llc Intraocular, accommodating lens and methods of use
WO2009088448A2 (fr) 2008-01-03 2009-07-16 Forsight Labs, Llc Lentille intraoculaire, d'accommodation et procédés d'utilisation
US7998198B2 (en) * 2008-02-07 2011-08-16 Novartis Ag Accommodative IOL with dynamic spherical aberration
US10485704B2 (en) 2013-04-18 2019-11-26 Optimedica Corporation Corneal topography measurement and alignment of corneal surgical procedures
US8034108B2 (en) 2008-03-28 2011-10-11 Abbott Medical Optics Inc. Intraocular lens having a haptic that includes a cap
EP2177179B1 (fr) * 2008-10-15 2011-06-15 Carl Zeiss Meditec France S.A.S. Procédé pour le modelage d'une lentille intraoculaire et lentille intraoculaire
GB2468367B (en) * 2009-05-27 2011-02-16 See Again Europ Ltd Intraocular lens systems and methods
AU2010266020B2 (en) 2009-06-26 2015-03-26 Johnson & Johnson Surgical Vision, Inc. Accommodating intraocular lenses
US8343217B2 (en) 2009-08-03 2013-01-01 Abbott Medical Optics Inc. Intraocular lens and methods for providing accommodative vision
DE112010004191T5 (de) * 2009-10-30 2012-11-22 Akkolens International B.V. Intraokulare Linsen für einen variablen Brennpunkt
ES2907929T3 (es) * 2009-11-17 2022-04-27 Akkolens Int B V Lente intraocular acomodativa accionada por masa ciliar
US9220590B2 (en) 2010-06-10 2015-12-29 Z Lens, Llc Accommodative intraocular lens and method of improving accommodation
US9931200B2 (en) 2010-12-17 2018-04-03 Amo Groningen B.V. Ophthalmic devices, systems, and methods for optimizing peripheral vision
WO2012106673A1 (fr) 2011-02-04 2012-08-09 Forsight Labs, Llc Lentille intraoculaire d'accommodation
US9084674B2 (en) 2012-05-02 2015-07-21 Abbott Medical Optics Inc. Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity
US9364318B2 (en) 2012-05-10 2016-06-14 Z Lens, Llc Accommodative-disaccommodative intraocular lens
AU2014228357B2 (en) * 2013-03-11 2018-08-23 Johnson & Johnson Surgical Vision, Inc. Intraocular lens that matches an image surface to a retinal shape, and method of designing same
EP3116444A2 (fr) 2014-03-10 2017-01-18 Amo Groningen B.V. Lentille intra-oculaire formant doublet qui améliore la vision globale en cas de perte localisée de la fonction rétinienne
EP3122287B1 (fr) 2014-03-28 2020-09-02 ForSight Vision6, Inc. Lentille intraoculaire d'accommodation
EP3134031A1 (fr) 2014-04-21 2017-03-01 Amo Groningen B.V. Dispositifs ophtalmiques, système et procédés qui améliorent la vision périphérique
US10299910B2 (en) 2014-09-22 2019-05-28 Kevin J. Cady Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US10159562B2 (en) 2014-09-22 2018-12-25 Kevin J. Cady Intraocular pseudophakic contact lenses and related systems and methods
US10945832B2 (en) 2014-09-22 2021-03-16 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US11938018B2 (en) 2014-09-22 2024-03-26 Onpoint Vision, Inc. Intraocular pseudophakic contact lens (IOPCL) for treating age-related macular degeneration (AMD) or other eye disorders
US11109957B2 (en) 2014-09-22 2021-09-07 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
CA3017293A1 (fr) 2016-03-11 2017-09-14 Amo Groningen B.V. Lentilles intraoculaires ameliorant la vision peripherique
CA3021474A1 (fr) 2016-04-19 2017-10-26 Amo Groningen B.V. Dispositifs ophtalmiques, systeme et procedes qui ameliorent la vision peripherique
EP3503843B1 (fr) 2016-08-24 2023-11-15 Carl Zeiss Meditec AG Lentille intraoculaire à double mode d'accommodation-désacommodation
JP7340450B2 (ja) 2016-10-28 2023-09-07 フォーサイト ビジョン６，インコーポレイテッド 調節性眼内レンズおよびインプラントの方法
AU2018330604A1 (en) 2017-09-11 2020-04-02 Amo Groningen B.V. Methods and apparatuses to increase intraocular lenses positional stability
CN113751892B (zh) * 2021-08-24 2023-09-19 广东宏石激光技术股份有限公司 一种基于激光光斑能量整形的厚材切割系统

Citations (4)

* Cited by examiner, † Cited by third party
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US4435856A (en) * 1982-04-14 1984-03-13 Esperance Francis A L Bifocal intraocular lens structure and spectacle actuation frame
US4816031A (en) * 1988-01-29 1989-03-28 Pfoff David S Intraocular lens system
US4994082A (en) * 1988-09-09 1991-02-19 Ophthalmic Ventures Limited Partnership Accommodating intraocular lens
US5391202A (en) * 1993-02-04 1995-02-21 Lipshitz; Isaac Intraocular insert for implantation in the human eye

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US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US5876442A (en) * 1998-01-15 1999-03-02 Visioncare Ltd. Intraocular lens implant with telescope support
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US4435856A (en) * 1982-04-14 1984-03-13 Esperance Francis A L Bifocal intraocular lens structure and spectacle actuation frame
US4816031A (en) * 1988-01-29 1989-03-28 Pfoff David S Intraocular lens system
US4994082A (en) * 1988-09-09 1991-02-19 Ophthalmic Ventures Limited Partnership Accommodating intraocular lens
US5391202A (en) * 1993-02-04 1995-02-21 Lipshitz; Isaac Intraocular insert for implantation in the human eye

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7662179B2 (en) 1999-04-09 2010-02-16 Sarfarazi Faezeh M Haptics for accommodative intraocular lens system
US8556967B2 (en) 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US9149356B2 (en) 1999-04-09 2015-10-06 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector

Also Published As

Publication number Publication date
US20050060032A1 (en) 2005-03-17
WO2003000154B1 (fr) 2005-07-28
EP1399097A2 (fr) 2004-03-24
WO2003000154A2 (fr) 2003-01-03
AU2002315375A1 (en) 2003-01-08
EP1399097A4 (fr) 2005-04-27

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