WO2002092759A3 - Molecules for disease detection and treatment - Google Patents

Molecules for disease detection and treatment Download PDF

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Publication number
WO2002092759A3
WO2002092759A3 PCT/US2002/013392 US0213392W WO02092759A3 WO 2002092759 A3 WO2002092759 A3 WO 2002092759A3 US 0213392 W US0213392 W US 0213392W WO 02092759 A3 WO02092759 A3 WO 02092759A3
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WO
WIPO (PCT)
Prior art keywords
treatment
disease detection
molecules
mddt
provides
Prior art date
Application number
PCT/US2002/013392
Other languages
French (fr)
Other versions
WO2002092759A9 (en
WO2002092759A2 (en
Inventor
Preeti G Lal
Henry Yue
Yan Lu
Monique G Yao
Shanya D Becha
Neil Burford
Mariah R Baughn
Y Tom Tang
Mark L Borowsky
Vicki S Elliott
Original Assignee
Incyte Genomics Inc
Preeti G Lal
Henry Yue
Yan Lu
Monique G Yao
Shanya D Becha
Neil Burford
Mariah R Baughn
Y Tom Tang
Mark L Borowsky
Vicki S Elliott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Preeti G Lal, Henry Yue, Yan Lu, Monique G Yao, Shanya D Becha, Neil Burford, Mariah R Baughn, Y Tom Tang, Mark L Borowsky, Vicki S Elliott filed Critical Incyte Genomics Inc
Priority to JP2002589627A priority Critical patent/JP2005505251A/en
Priority to CA002445366A priority patent/CA2445366A1/en
Priority to EP02749524A priority patent/EP1390396A4/en
Priority to AU2002320026A priority patent/AU2002320026A1/en
Publication of WO2002092759A2 publication Critical patent/WO2002092759A2/en
Publication of WO2002092759A3 publication Critical patent/WO2002092759A3/en
Publication of WO2002092759A9 publication Critical patent/WO2002092759A9/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
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    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
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  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)

Abstract

The invention provides human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.
PCT/US2002/013392 2001-04-27 2002-04-25 Molecules for disease detection and treatment WO2002092759A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002589627A JP2005505251A (en) 2001-04-27 2002-04-25 Disease detection and therapeutic molecules
CA002445366A CA2445366A1 (en) 2001-04-27 2002-04-25 Molecules for disease detection and treatment
EP02749524A EP1390396A4 (en) 2001-04-27 2002-04-25 Molecules for disease detection and treatment
AU2002320026A AU2002320026A1 (en) 2001-04-27 2002-04-25 Molecules for disease detection and treatment

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US28715201P 2001-04-27 2001-04-27
US60/287,152 2001-04-27
US28859901P 2001-05-04 2001-05-04
US60/288,599 2001-05-04
US29036401P 2001-05-11 2001-05-11
US60/290,364 2001-05-11
US29383701P 2001-05-24 2001-05-24
US60/293,837 2001-05-24
US35110702P 2002-01-22 2002-01-22
US60/351,107 2002-01-22
US35328402P 2002-02-01 2002-02-01
US60/353,284 2002-02-01

Publications (3)

Publication Number Publication Date
WO2002092759A2 WO2002092759A2 (en) 2002-11-21
WO2002092759A3 true WO2002092759A3 (en) 2003-10-02
WO2002092759A9 WO2002092759A9 (en) 2005-03-24

Family

ID=27559588

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/013392 WO2002092759A2 (en) 2001-04-27 2002-04-25 Molecules for disease detection and treatment

Country Status (4)

Country Link
JP (1) JP2005505251A (en)
AU (1) AU2002320026A1 (en)
CA (1) CA2445366A1 (en)
WO (1) WO2002092759A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1563056A4 (en) * 2002-11-21 2005-12-28 Wyeth Corp Composition and method for treating lupus nephritis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BRITTON ET AL.: "The third human FRE-1-like protein is highly similar to dysferlin", GENOMICS, vol. 68, 2000, pages 313 - 321, XP002961572 *
See also references of EP1390396A4 *

Also Published As

Publication number Publication date
WO2002092759A9 (en) 2005-03-24
JP2005505251A (en) 2005-02-24
AU2002320026A1 (en) 2002-11-25
CA2445366A1 (en) 2002-11-21
WO2002092759A2 (en) 2002-11-21

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