WO2002046413A3 - Molecules for disease detection and treatment - Google Patents

Molecules for disease detection and treatment Download PDF

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Publication number
WO2002046413A3
WO2002046413A3 PCT/US2001/046874 US0146874W WO0246413A3 WO 2002046413 A3 WO2002046413 A3 WO 2002046413A3 US 0146874 W US0146874 W US 0146874W WO 0246413 A3 WO0246413 A3 WO 0246413A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
mddt
disease detection
molecules
provides
Prior art date
Application number
PCT/US2001/046874
Other languages
French (fr)
Other versions
WO2002046413A2 (en
Inventor
Jennifer L Jackson
Mariah R Baughn
Henry Yue
Kimberly J Gietzen
Y Tom Tang
Kavitha Thangavelu
Preeti G Lal
Yuming Xu
Vicki S Elliott
Dyung Aina M Lu
Monique G Yao
Yan Lu
April J A Hafalia
Jayalaxmi Ramkumar
Original Assignee
Incyte Genomics Inc
Jennifer L Jackson
Mariah R Baughn
Henry Yue
Kimberly J Gietzen
Y Tom Tang
Kavitha Thangavelu
Preeti G Lal
Yuming Xu
Vicki S Elliott
Dyung Aina M Lu
Monique G Yao
Yan Lu
April J A Hafalia
Jayalaxmi Ramkumar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Jennifer L Jackson, Mariah R Baughn, Henry Yue, Kimberly J Gietzen, Y Tom Tang, Kavitha Thangavelu, Preeti G Lal, Yuming Xu, Vicki S Elliott, Dyung Aina M Lu, Monique G Yao, Yan Lu, April J A Hafalia, Jayalaxmi Ramkumar filed Critical Incyte Genomics Inc
Priority to AU2002239543A priority Critical patent/AU2002239543A1/en
Priority to US10/433,544 priority patent/US20040053396A1/en
Publication of WO2002046413A2 publication Critical patent/WO2002046413A2/en
Publication of WO2002046413A3 publication Critical patent/WO2002046413A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides full-length human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.
PCT/US2001/046874 2000-12-07 2001-12-04 Molecules for disease detection and treatment WO2002046413A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002239543A AU2002239543A1 (en) 2000-12-07 2001-12-04 Molecules for disease detection and treatment
US10/433,544 US20040053396A1 (en) 2001-12-04 2001-12-04 Molecules for disease detection and treatment

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25179100P 2000-12-07 2000-12-07
US60/251,791 2000-12-07

Publications (2)

Publication Number Publication Date
WO2002046413A2 WO2002046413A2 (en) 2002-06-13
WO2002046413A3 true WO2002046413A3 (en) 2003-09-04

Family

ID=22953419

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046874 WO2002046413A2 (en) 2000-12-07 2001-12-04 Molecules for disease detection and treatment

Country Status (2)

Country Link
AU (1) AU2002239543A1 (en)
WO (1) WO2002046413A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1282696A4 (en) * 2000-03-13 2005-02-09 Curagen Corp Ifi206, a novel interferon-induced polypeptide, and nucleic acids encoding the same
US20040152092A1 (en) * 2001-05-11 2004-08-05 Alex Smolyar Regulation of human phosphatidic acid phosphatase type 2c-like protein
US20070142288A1 (en) * 2005-12-20 2007-06-21 Pappachan Kolattukudy Isolated MCPIP and methods of use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999004265A2 (en) * 1997-07-17 1999-01-28 Ludwig Institute For Cancer Research Cancer associated nucleic acids and polypeptides
WO2001057188A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999004265A2 (en) * 1997-07-17 1999-01-28 Ludwig Institute For Cancer Research Cancer associated nucleic acids and polypeptides
WO2001057188A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 February 2000 (2000-02-01), XP002223626, retrieved from EBI Database accession no. AW337474 *
JOHNSTONE RICKY W ET AL: "The human interferon-inducible protein, IFI 16, is a repressor of transcription.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 27, 3 July 1998 (1998-07-03), pages 17172 - 17177, XP002223625, ISSN: 0021-9258 *
TRAPANI J A ET AL: "A NOVEL GENE CONSTITUTIVELY EXPRESSED IN HUMAN LYMPHOID CELLS IS INDUCIBLE WITH INTERFERON-GAMMA IN MYELOID CELLS", IMMUNOGENETICS, SPRINGER VERLAG, BERLIN, DE, vol. 36, no. 6, 1 September 1992 (1992-09-01), pages 369 - 376, XP000605287, ISSN: 0093-7711 *
TRAPANI J A ET AL: "GENOMIC ORGANIZATION OF IFI16, AN INTERFERON-INDUCIBLE GENE WHOSE EXPRESSION IS ASSOCIATED WITH HUMAN MYELOIS CELL DIFFERENTIATION: CORRELATION OF PREDICTED PROTEIN DOMAINS WITH EXON ORGANIZATION", IMMUNOGENETICS, SPRINGER VERLAG, BERLIN, DE, vol. 40, no. 6, 1 October 1994 (1994-10-01), pages 415 - 424, XP000576202, ISSN: 0093-7711 *

Also Published As

Publication number Publication date
WO2002046413A2 (en) 2002-06-13
AU2002239543A1 (en) 2002-06-18

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