WO2002088725A3 - Marqueur biopolymere indicateur d'un etat pathologique possedant un poids moleculaire de 1793 daltons - Google Patents

Marqueur biopolymere indicateur d'un etat pathologique possedant un poids moleculaire de 1793 daltons Download PDF

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Publication number
WO2002088725A3
WO2002088725A3 PCT/CA2002/000614 CA0200614W WO02088725A3 WO 2002088725 A3 WO2002088725 A3 WO 2002088725A3 CA 0200614 W CA0200614 W CA 0200614W WO 02088725 A3 WO02088725 A3 WO 02088725A3
Authority
WO
WIPO (PCT)
Prior art keywords
daltons
molecular weight
absence
ability
biopolymer marker
Prior art date
Application number
PCT/CA2002/000614
Other languages
English (en)
Other versions
WO2002088725A2 (fr
Inventor
George Jackowski
Brad Thatcher
Tammy Vrees
Jason Yantha
John Marshall
Original Assignee
Syn X Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syn X Pharma Inc filed Critical Syn X Pharma Inc
Priority to AU2002254828A priority Critical patent/AU2002254828A1/en
Publication of WO2002088725A2 publication Critical patent/WO2002088725A2/fr
Publication of WO2002088725A3 publication Critical patent/WO2002088725A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Abstract

La présente invenion concerne l'utilisation d'une combinaison d'étapes préparatoires conjointement à des procédures de spectroscopie de masse et de détection de temps de vol afin de maximiser la diversité des biopolymères pouvant être vérifiés dans un échantillon particulier. L'ensemble des biopolymères vérifiés dans un tel échantillon sont alors visualisés par rapport à leur capacité à mettre en évidence au moins un état pathologique particulier, permettant ainsi à la personne chargée du diagnostic de caractériser la présence ou l'absence de cet état pathologique par la reconnaissance de la présence et/ou de l'absence dudit biopolymère.
PCT/CA2002/000614 2001-04-30 2002-04-26 Marqueur biopolymere indicateur d'un etat pathologique possedant un poids moleculaire de 1793 daltons WO2002088725A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002254828A AU2002254828A1 (en) 2001-04-30 2002-04-26 Biopolymer marker having a molecular weight of 1793 daltons

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/845,739 2001-04-30
US09/845,739 US6998243B2 (en) 2001-04-30 2001-04-30 Biopolymer marker indicative of disease state having a molecular weight of 1793 daltons

Publications (2)

Publication Number Publication Date
WO2002088725A2 WO2002088725A2 (fr) 2002-11-07
WO2002088725A3 true WO2002088725A3 (fr) 2003-01-03

Family

ID=25295990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2002/000614 WO2002088725A2 (fr) 2001-04-30 2002-04-26 Marqueur biopolymere indicateur d'un etat pathologique possedant un poids moleculaire de 1793 daltons

Country Status (3)

Country Link
US (1) US6998243B2 (fr)
AU (1) AU2002254828A1 (fr)
WO (1) WO2002088725A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0300586L (sv) 2003-03-04 2004-09-05 Forskarpatent I Syd Ab Diagnos av autism
US9347956B2 (en) 2010-12-16 2016-05-24 Autism Biotech Limited Biomarker and uses thereof in diagnosis, treatment of autism

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006344A1 (fr) * 1986-04-11 1987-10-22 Nilsson Ulf R Preparation d'un anticorps contre des neoantigenes dans le facteur complementaire humain c3, son utilisation et sa fabrication
WO1991013352A1 (fr) * 1990-03-02 1991-09-05 Brigham And Women's Hospital Composants du complement et ligands de liaison en fecondite
US5538897A (en) * 1994-03-14 1996-07-23 University Of Washington Use of mass spectrometry fragmentation patterns of peptides to identify amino acid sequences in databases
WO1998032390A1 (fr) * 1997-01-29 1998-07-30 The Uab Research Foundation Procede permettant de distinguer meningite bacterienne et meningite aseptique
WO2000049410A2 (fr) * 1999-02-16 2000-08-24 The Government Of The United States Of America, As Represented By The Secretary Department Of Health & Human Services, The National Institutes Of Health Procedes et dispositifs d'isolation et d'analyse de la teneur proteique des cellules
WO2001005422A2 (fr) * 1999-07-15 2001-01-25 Biomerieux Stelhys Utilisation d'un polypeptique pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique autoimmune

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL319040A1 (en) * 1994-09-08 1997-07-21 Imutran Ltd Modified proteins
US6221657B1 (en) * 1995-09-08 2001-04-24 Imutran Limited Modified human C3 DNA sequences and vectors
CZ283598A3 (cs) * 1996-03-07 1999-02-17 Imutran Ltd. C3-konvertáza rezistentní k regulačnímu snížení aktivity
US6617308B2 (en) * 2001-04-30 2003-09-09 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1865 daltons

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006344A1 (fr) * 1986-04-11 1987-10-22 Nilsson Ulf R Preparation d'un anticorps contre des neoantigenes dans le facteur complementaire humain c3, son utilisation et sa fabrication
WO1991013352A1 (fr) * 1990-03-02 1991-09-05 Brigham And Women's Hospital Composants du complement et ligands de liaison en fecondite
US5538897A (en) * 1994-03-14 1996-07-23 University Of Washington Use of mass spectrometry fragmentation patterns of peptides to identify amino acid sequences in databases
WO1998032390A1 (fr) * 1997-01-29 1998-07-30 The Uab Research Foundation Procede permettant de distinguer meningite bacterienne et meningite aseptique
WO2000049410A2 (fr) * 1999-02-16 2000-08-24 The Government Of The United States Of America, As Represented By The Secretary Department Of Health & Human Services, The National Institutes Of Health Procedes et dispositifs d'isolation et d'analyse de la teneur proteique des cellules
WO2001005422A2 (fr) * 1999-07-15 2001-01-25 Biomerieux Stelhys Utilisation d'un polypeptique pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique autoimmune

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AGARWAL R ET AL: "Immunologic parameters in infective endocarditis: a prospective study.", INDIAN HEART JOURNAL. INDIA 1991 MAY-JUN, vol. 43, no. 3, May 1991 (1991-05-01), pages 179 - 183, XP008008224, ISSN: 0019-4832 *
HARRISON, RICHARD A. ET AL: "Structure of C3f, a small peptide specifically released during inactivation of the third component of complement", COMPLEMENT, vol. 5, no. 1, 1988, pages 27 - 32, XP008007942 *
KOCH C ET AL: "A novel polymorphism of human complement component C3 detected by means of a monoclonal antibody.", IMMUNOGENETICS. UNITED STATES 1986, vol. 23, no. 5, 1986, pages 322 - 325, XP008008260, ISSN: 0093-7711 *
KRISTENSEN B O ET AL: "ASSOCIATION BETWEEN CORONARY HEART DISEASE AND THE COMPLEMENT C-3F GENE IN ESSENTIAL HYPERTENSION", CIRCULATION, vol. 58, no. 4, 1978, pages 622 - 625, XP008008221, ISSN: 0009-7322 *
TANG S ET AL: "Contribution of renal secreted complement C3 to the circulating pool in humans.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD.: 1950) UNITED STATES 1 APR 1999, vol. 162, no. 7, 1 April 1999 (1999-04-01), pages 4336 - 4341, XP002213827, ISSN: 0022-1767 *

Also Published As

Publication number Publication date
US6998243B2 (en) 2006-02-14
AU2002254828A1 (en) 2002-11-11
WO2002088725A2 (fr) 2002-11-07
US20020160419A1 (en) 2002-10-31

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