WO2002072855A3 - Process for the preparation of d-pantothenic acid and/or salts thereof - Google Patents

Process for the preparation of d-pantothenic acid and/or salts thereof Download PDF

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Publication number
WO2002072855A3
WO2002072855A3 PCT/EP2002/001830 EP0201830W WO02072855A3 WO 2002072855 A3 WO2002072855 A3 WO 2002072855A3 EP 0201830 W EP0201830 W EP 0201830W WO 02072855 A3 WO02072855 A3 WO 02072855A3
Authority
WO
WIPO (PCT)
Prior art keywords
pantothenic acid
salts
preparation
microorganisms
attenuated
Prior art date
Application number
PCT/EP2002/001830
Other languages
French (fr)
Other versions
WO2002072855A2 (en
Inventor
Mechthild Rieping
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Priority to AU2002233353A priority Critical patent/AU2002233353A1/en
Publication of WO2002072855A2 publication Critical patent/WO2002072855A2/en
Publication of WO2002072855A3 publication Critical patent/WO2002072855A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Abstract

The invention provides a process for the preparation of D-pantothenic acid and/or salts thereof or feedstuffs additives comprising these, by fermentation of microorganisms of the Enterobacteriaceae family, in particular those which already produce D-pantothenic acid, wherein the nucleotide sequence(s) in the microorganisms which code(s) for the poxB gene is (are) attenuated, in particular eliminated.
PCT/EP2002/001830 2001-03-14 2002-02-21 Process for the preparation of d-pantothenic acid and/or salts thereof WO2002072855A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002233353A AU2002233353A1 (en) 2001-03-14 2002-02-21 Process for the preparation of d-pantothenic acid and/or salts thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10112102.4 2001-03-14
DE10112102A DE10112102A1 (en) 2001-03-14 2001-03-14 Process for the fermentative production of D-pantothenic acid and / or its salts

Publications (2)

Publication Number Publication Date
WO2002072855A2 WO2002072855A2 (en) 2002-09-19
WO2002072855A3 true WO2002072855A3 (en) 2003-02-13

Family

ID=7677320

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/001830 WO2002072855A2 (en) 2001-03-14 2002-02-21 Process for the preparation of d-pantothenic acid and/or salts thereof

Country Status (3)

Country Link
AU (1) AU2002233353A1 (en)
DE (1) DE10112102A1 (en)
WO (1) WO2002072855A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4469568B2 (en) 2003-07-09 2010-05-26 三菱化学株式会社 Method for producing organic acid
CN100575496C (en) 2003-08-28 2009-12-30 三菱化学株式会社 Produce the method for succsinic acid
JP4619291B2 (en) 2003-09-17 2011-01-26 三菱化学株式会社 Method for producing non-amino organic acid
CN1989238B (en) 2004-05-20 2010-05-26 味之素株式会社 Succinic acid-producing bacterium and process for producing succinic acid
JP4595506B2 (en) 2004-11-25 2010-12-08 味の素株式会社 L-amino acid-producing bacterium and method for producing L-amino acid
EP1947190B1 (en) 2005-10-18 2017-11-29 Ajinomoto Co., Inc. Process for production of succinic acid
EP1995308B1 (en) 2006-02-24 2014-07-30 Mitsubishi Chemical Corporation Bacterium capable of producing organic acid, and method for production of organic acid
DE112007001179T5 (en) 2006-05-16 2009-04-02 Dsm Ip Assets B.V. Process for the preparation of panthenol
CN113278569B (en) * 2021-05-11 2022-04-19 浙江工业大学 Plasmid-free and inducer-free gene engineering bacterium for producing D-pantothenic acid and construction method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4278765A (en) * 1978-06-30 1981-07-14 Debabov Vladimir G Method for preparing strains which produce aminoacids
EP0590857A2 (en) * 1992-09-25 1994-04-06 Takeda Chemical Industries, Ltd. Production of D-pantoic acid and D-pantothenic acid
EP1006193A2 (en) * 1998-12-01 2000-06-07 Degussa-Hüls Aktiengesellschaft Method for the fermantative production of D-pantothenic acid using Enterobacteriaceae strains
WO2002029020A1 (en) * 2000-09-30 2002-04-11 Degussa Ag Process for the fermentative preparation of d-pantothenic acid using coryneform bacteria
WO2002036797A2 (en) * 2000-11-04 2002-05-10 Degussa Ag Process for the fermentative preparation of l-amino acids using strains of the enterobacteriaceae family

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4278765A (en) * 1978-06-30 1981-07-14 Debabov Vladimir G Method for preparing strains which produce aminoacids
EP0590857A2 (en) * 1992-09-25 1994-04-06 Takeda Chemical Industries, Ltd. Production of D-pantoic acid and D-pantothenic acid
EP1006193A2 (en) * 1998-12-01 2000-06-07 Degussa-Hüls Aktiengesellschaft Method for the fermantative production of D-pantothenic acid using Enterobacteriaceae strains
WO2002029020A1 (en) * 2000-09-30 2002-04-11 Degussa Ag Process for the fermentative preparation of d-pantothenic acid using coryneform bacteria
WO2002036797A2 (en) * 2000-11-04 2002-05-10 Degussa Ag Process for the fermentative preparation of l-amino acids using strains of the enterobacteriaceae family

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GRABAU C ET AL: "MOLECULAR CLONING OF THE GENE (POXB) ENCODING THE PYRUVATE OXIDASE OF ESCHERICHIA COLI, A LIPID-ACTIVATED ENZYME", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 160, no. 3, December 1984 (1984-12-01), pages 1088 - 1092, XP000987282, ISSN: 0021-9193 *

Also Published As

Publication number Publication date
AU2002233353A1 (en) 2002-09-24
DE10112102A1 (en) 2002-09-19
WO2002072855A2 (en) 2002-09-19

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