WO2002060508A8 - Biodegradable porous scaffold material - Google Patents

Biodegradable porous scaffold material

Info

Publication number
WO2002060508A8
WO2002060508A8 PCT/NL2002/000066 NL0200066W WO02060508A8 WO 2002060508 A8 WO2002060508 A8 WO 2002060508A8 NL 0200066 W NL0200066 W NL 0200066W WO 02060508 A8 WO02060508 A8 WO 02060508A8
Authority
WO
WIPO (PCT)
Prior art keywords
scaffold material
porous scaffold
biodegradable porous
copolymer
relates
Prior art date
Application number
PCT/NL2002/000066
Other languages
French (fr)
Other versions
WO2002060508A1 (en
Inventor
Jeroen Mattijs Bezemer
Wijn Joost Robert De
Robert Edgar Haan
Monica Blom
Original Assignee
Isotis Nv
Jeroen Mattijs Bezemer
Wijn Joost Robert De
Robert Edgar Haan
Monica Blom
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isotis Nv, Jeroen Mattijs Bezemer, Wijn Joost Robert De, Robert Edgar Haan, Monica Blom filed Critical Isotis Nv
Publication of WO2002060508A1 publication Critical patent/WO2002060508A1/en
Publication of WO2002060508A8 publication Critical patent/WO2002060508A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges

Abstract

The invention relates to a method for the preparation of a porousbody of a biodegradable material comprising the steps of mixing a copolymer of polyakylene glycol terephtalate and an aromatic polyester with particles that are soluble in a solvent in which the copolymer essentially does not dissolve, and subjecting the obtained mixture to heat and/or pressure sufficiently long for forming the body. The invention further relates to a porous body obtainable by said method and to its use as a scaffold for tissue engineering or as a medical implant.
PCT/NL2002/000066 2001-01-30 2002-01-29 Biodegradable porous scaffold material WO2002060508A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200328.1 2001-01-30
EP01200328 2001-01-30

Publications (2)

Publication Number Publication Date
WO2002060508A1 WO2002060508A1 (en) 2002-08-08
WO2002060508A8 true WO2002060508A8 (en) 2003-11-06

Family

ID=8179822

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2002/000066 WO2002060508A1 (en) 2001-01-30 2002-01-29 Biodegradable porous scaffold material

Country Status (1)

Country Link
WO (1) WO2002060508A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1247537A1 (en) 2001-04-04 2002-10-09 Isotis B.V. Coating for medical devices
ATE546172T1 (en) * 2004-03-22 2012-03-15 Agency Science Tech & Res METHOD FOR OBTAINING A GRADED PORE STRUCTURE IN TISSUE AND BONE SCAFFOLDS
US20060018948A1 (en) * 2004-06-24 2006-01-26 Guire Patrick E Biodegradable implantable medical devices, methods and systems
US20060024350A1 (en) * 2004-06-24 2006-02-02 Varner Signe E Biodegradable ocular devices, methods and systems
PT3626208T (en) 2010-10-05 2021-04-22 Edwards Lifesciences Corp Prosthetic heart valve

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1412983A (en) * 1971-11-30 1975-11-05 Debell & Richardson Method of producing porous plastic materials
US6255359B1 (en) * 1997-12-23 2001-07-03 Board Of Regents Of The University Of Texas System Permeable compositions and methods for their preparation
EP1002859A1 (en) * 1998-11-10 2000-05-24 Isotis B.V. Seeding of cells
US6103255A (en) * 1999-04-16 2000-08-15 Rutgers, The State University Porous polymer scaffolds for tissue engineering
EP1068872A1 (en) * 1999-07-12 2001-01-17 IsoTis B.V. Sutures

Also Published As

Publication number Publication date
WO2002060508A1 (en) 2002-08-08

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