WO2002053752A3 - Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof - Google Patents

Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof Download PDF

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Publication number
WO2002053752A3
WO2002053752A3 PCT/US2002/000135 US0200135W WO02053752A3 WO 2002053752 A3 WO2002053752 A3 WO 2002053752A3 US 0200135 W US0200135 W US 0200135W WO 02053752 A3 WO02053752 A3 WO 02053752A3
Authority
WO
WIPO (PCT)
Prior art keywords
human phosphatase
phosphatase proteins
nucleic acid
acid molecules
molecules encoding
Prior art date
Application number
PCT/US2002/000135
Other languages
French (fr)
Other versions
WO2002053752A2 (en
Inventor
Ming-Hui Wei
Karen A Ketchum
Francesco Valentina Di
Ellen M Beasley
Original Assignee
Pe Corp Ny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/752,820 external-priority patent/US20020107170A1/en
Application filed by Pe Corp Ny filed Critical Pe Corp Ny
Priority to EP02708946A priority Critical patent/EP1349942A2/en
Priority to AU2002243460A priority patent/AU2002243460A1/en
Priority to CA002433749A priority patent/CA2433749A1/en
Publication of WO2002053752A2 publication Critical patent/WO2002053752A2/en
Publication of WO2002053752A3 publication Critical patent/WO2002053752A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03016—Phosphoprotein phosphatase (3.1.3.16), i.e. calcineurin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphatase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphatase peptides, and methods of identifying modulators of the phosphatase peptides.
PCT/US2002/000135 2001-01-03 2002-01-02 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof WO2002053752A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02708946A EP1349942A2 (en) 2001-01-03 2002-01-02 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof
AU2002243460A AU2002243460A1 (en) 2001-01-03 2002-01-02 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof
CA002433749A CA2433749A1 (en) 2001-01-03 2002-01-02 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/752,820 US20020107170A1 (en) 2001-01-03 2001-01-03 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof
US09/752,820 2001-01-03
US09/813,319 US20020108133A1 (en) 2001-01-03 2001-03-21 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof
US09/813,319 2001-03-21

Publications (2)

Publication Number Publication Date
WO2002053752A2 WO2002053752A2 (en) 2002-07-11
WO2002053752A3 true WO2002053752A3 (en) 2003-04-17

Family

ID=27115656

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/000135 WO2002053752A2 (en) 2001-01-03 2002-01-02 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof

Country Status (3)

Country Link
EP (1) EP1349942A2 (en)
CA (1) CA2433749A1 (en)
WO (1) WO2002053752A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035018A1 (en) * 1996-03-21 1997-09-25 New York University Growth factor inducible serine/threonine phosphatase fin13
EP0874052A2 (en) * 1997-04-22 1998-10-28 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Nucleic acid encoding a human protein phosphatase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035018A1 (en) * 1996-03-21 1997-09-25 New York University Growth factor inducible serine/threonine phosphatase fin13
EP0874052A2 (en) * 1997-04-22 1998-10-28 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Nucleic acid encoding a human protein phosphatase

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
[online] XP002228581, Database accession no. AI016791 *
[online] XP002228582, Database accession no. AI949680 *
BARTON G J: "PROTEIN SEQUENCE ALIGMENT AND DATABASE SCANNING", PROTEIN STRUCTURE PREDICTION. A PRACTICAL APPROACH, XX, XX, 1996, pages 31 - 63, XP000829540 *
GEORGE D G ET AL: "CURRENT METHODS IN SEQUENCE COMPARISON AND ANALYSIS", MACROMOLECULAR SEQUENCING AND SYNTHESIS SELECTED METHODS AND APPLICATIONS, XX, XX, 1988, pages 127 - 149, XP000829541 *
TRAVIS S M ET AL: "PP2Cgamma: a human protein phosphatase with a unique acidic domain", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 412, no. 3, 1 August 1997 (1997-08-01), pages 415 - 419, XP002085149, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
CA2433749A1 (en) 2002-07-11
EP1349942A2 (en) 2003-10-08
WO2002053752A2 (en) 2002-07-11

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