WO2002042436A3 - Isolated human phosphatase proteins, nucleic acid molecules encoding them, and uses thereof - Google Patents

Isolated human phosphatase proteins, nucleic acid molecules encoding them, and uses thereof Download PDF

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Publication number
WO2002042436A3
WO2002042436A3 PCT/US2001/042995 US0142995W WO0242436A3 WO 2002042436 A3 WO2002042436 A3 WO 2002042436A3 US 0142995 W US0142995 W US 0142995W WO 0242436 A3 WO0242436 A3 WO 0242436A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
molecules encoding
isolated human
human phosphatase
Prior art date
Application number
PCT/US2001/042995
Other languages
French (fr)
Other versions
WO2002042436A2 (en
Inventor
Ming-Hui Wei
Karen A Ketchum
Francesco Valentina Di
Ellen M Beasley
Original Assignee
Pe Corp Ny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/761,640 external-priority patent/US20020137042A1/en
Application filed by Pe Corp Ny filed Critical Pe Corp Ny
Priority to AU2002228599A priority Critical patent/AU2002228599A1/en
Priority to JP2002545141A priority patent/JP2004514434A/en
Priority to EP01989711A priority patent/EP1317531A2/en
Priority to CA002398924A priority patent/CA2398924A1/en
Publication of WO2002042436A2 publication Critical patent/WO2002042436A2/en
Publication of WO2002042436A3 publication Critical patent/WO2002042436A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphatase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphatase peptides, and methods of identifying modulators of the phosphatase peptides.
PCT/US2001/042995 2000-11-20 2001-11-07 Isolated human phosphatase proteins, nucleic acid molecules encoding them, and uses thereof WO2002042436A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2002228599A AU2002228599A1 (en) 2000-11-20 2001-11-07 Isolated human phosphatase proteins, nucleic acid molecules encoding them, and uses thereof
JP2002545141A JP2004514434A (en) 2000-11-20 2001-11-07 Isolated human phosphatase protein, nucleic acid molecule encoding human phosphatase protein and uses thereof
EP01989711A EP1317531A2 (en) 2000-11-20 2001-11-07 Isolated human phosphatase proteins, nucleic acid molecules encoding them, and uses thereof
CA002398924A CA2398924A1 (en) 2000-11-20 2001-11-07 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71517700A 2000-11-20 2000-11-20
US09/715,177 2000-11-20
US09/761,640 2001-01-18
US09/761,640 US20020137042A1 (en) 2001-01-18 2001-01-18 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof

Publications (2)

Publication Number Publication Date
WO2002042436A2 WO2002042436A2 (en) 2002-05-30
WO2002042436A3 true WO2002042436A3 (en) 2003-02-27

Family

ID=27109287

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/042995 WO2002042436A2 (en) 2000-11-20 2001-11-07 Isolated human phosphatase proteins, nucleic acid molecules encoding them, and uses thereof

Country Status (5)

Country Link
EP (1) EP1317531A2 (en)
JP (1) JP2004514434A (en)
AU (1) AU2002228599A1 (en)
CA (1) CA2398924A1 (en)
WO (1) WO2002042436A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825021B2 (en) 2000-09-19 2004-11-30 Ceptyr, Inc. DSP-15 dual-specificity phosphatase

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001012819A2 (en) * 1999-08-13 2001-02-22 Sugen, Inc. Protein phosphatases and diagnosis and treatment of phosphatase-related disorders
WO2001020004A2 (en) * 1999-09-15 2001-03-22 Incyte Genomics, Inc. Protein phosphatase and kinase proteins
WO2002024740A2 (en) * 2000-09-19 2002-03-28 Ceptyr, Inc. Dsp-15 dual-specificity phosphatase

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001012819A2 (en) * 1999-08-13 2001-02-22 Sugen, Inc. Protein phosphatases and diagnosis and treatment of phosphatase-related disorders
WO2001020004A2 (en) * 1999-09-15 2001-03-22 Incyte Genomics, Inc. Protein phosphatase and kinase proteins
WO2002024740A2 (en) * 2000-09-19 2002-03-28 Ceptyr, Inc. Dsp-15 dual-specificity phosphatase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 22 February 2000 (2000-02-22), ISOGAI ET AL.: "Homo sapiens cDNA FLJ10928 fis", XP002217824, Database accession no. AK001790 *
DATABASE EMBL [online] 22 February 2000 (2000-02-22), SUGANO ET AL.: "Homo sapiens cDNA FLJ20515 fis", XP002217823, Database accession no. AK000522 *

Also Published As

Publication number Publication date
JP2004514434A (en) 2004-05-20
CA2398924A1 (en) 2002-05-30
AU2002228599A1 (en) 2002-06-03
WO2002042436A2 (en) 2002-05-30
EP1317531A2 (en) 2003-06-11

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