WO2002047706A3 - Selective cox-2 inhibition from plant extracts - Google Patents

Selective cox-2 inhibition from plant extracts Download PDF

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Publication number
WO2002047706A3
WO2002047706A3 PCT/US2001/048650 US0148650W WO0247706A3 WO 2002047706 A3 WO2002047706 A3 WO 2002047706A3 US 0148650 W US0148650 W US 0148650W WO 0247706 A3 WO0247706 A3 WO 0247706A3
Authority
WO
WIPO (PCT)
Prior art keywords
cox
inhibition
organism
plant extracts
selective cox
Prior art date
Application number
PCT/US2001/048650
Other languages
French (fr)
Other versions
WO2002047706A2 (en
Inventor
Mark G Obukowicz
Susan L Hummert
Original Assignee
Pharmacia Corp
Mark G Obukowicz
Susan L Hummert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp, Mark G Obukowicz, Susan L Hummert filed Critical Pharmacia Corp
Priority to EP01990211A priority Critical patent/EP1401460A2/en
Priority to US10/450,487 priority patent/US20040126438A1/en
Priority to JP2002549276A priority patent/JP2004529079A/en
Priority to AU2002229074A priority patent/AU2002229074A1/en
Publication of WO2002047706A2 publication Critical patent/WO2002047706A2/en
Publication of WO2002047706A3 publication Critical patent/WO2002047706A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention is directed toward a method for inhibiting COX-2 in an organism. In particular, the method is preferably directed toward selectively inhibiting COX-2 in an organism. The method comprises administering to the organism an organic extract isolated from a plant wherein such extract inhibits COX-2 . A method to purify a composition that exhibits COX-2 inhibition and COX-2 selective inhibition from the organic extract is also provided. In addition, a method for treating and/or preventing COX-2 mediated inflammation or inflammation-associated disorders in an organism is provided.
PCT/US2001/048650 2000-12-15 2001-12-13 Selective cox-2 inhibition from plant extracts WO2002047706A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01990211A EP1401460A2 (en) 2000-12-15 2001-12-13 Selective cox-2 inhibition from plant extracts
US10/450,487 US20040126438A1 (en) 2001-12-13 2001-12-13 Selective cox-2 inhibition from plant extracts
JP2002549276A JP2004529079A (en) 2000-12-15 2001-12-13 Selective COX-2 inhibition by plant extracts
AU2002229074A AU2002229074A1 (en) 2000-12-15 2001-12-13 Selective cox-2 inhibition from plant extracts

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30420700P 2000-12-15 2000-12-15
US60/304,207 2000-12-15

Publications (2)

Publication Number Publication Date
WO2002047706A2 WO2002047706A2 (en) 2002-06-20
WO2002047706A3 true WO2002047706A3 (en) 2003-12-31

Family

ID=23175530

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/048650 WO2002047706A2 (en) 2000-12-15 2001-12-13 Selective cox-2 inhibition from plant extracts

Country Status (5)

Country Link
US (2) US20020136784A1 (en)
EP (1) EP1401460A2 (en)
JP (1) JP2004529079A (en)
AU (1) AU2002229074A1 (en)
WO (1) WO2002047706A2 (en)

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CN104873415B (en) 2009-08-26 2018-01-23 玫琳凯有限公司 The method for handling skin
KR101167677B1 (en) * 2009-09-21 2012-07-20 한국생명공학연구원 A composition comprising extracts of Elaeocarpus petiolatus for prevention and treatment of inflammatory diseases
CN106074278B (en) 2010-09-09 2020-11-27 玫琳凯有限公司 Topical skin care formulations comprising plant extracts
WO2012077976A2 (en) * 2010-12-07 2012-06-14 한국생명공학연구원 Anti-aging composition containing elaeocarpus petiolatus extract or fraction thereof as active ingredient
KR101425560B1 (en) 2010-12-07 2014-08-04 한국생명공학연구원 Composition for antioxidant comprising extracts or its fractions of Elaeocarpus petiolatus as an active ingredient
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JP2014177454A (en) * 2013-02-18 2014-09-25 Kagoshima Univ Food and drink and pharmaceutical preparation containing nejime biwa tea extract
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EP3452176B1 (en) 2016-05-03 2021-06-23 Tauderma SA Saxifraga extracts for cosmetic or therapeutic use on the skin
KR101806031B1 (en) 2016-07-11 2017-12-08 한양대학교 에리카산학협력단 Anti-imflammatory active composition containing Macakurzin C or its derivatives, and method for producing thereof
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Also Published As

Publication number Publication date
WO2002047706A2 (en) 2002-06-20
AU2002229074A1 (en) 2002-06-24
JP2004529079A (en) 2004-09-24
US20040197429A1 (en) 2004-10-07
EP1401460A2 (en) 2004-03-31
US20020136784A1 (en) 2002-09-26

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