WO2002040541A3 - Transporters and ion channels - Google Patents

Transporters and ion channels Download PDF

Info

Publication number
WO2002040541A3
WO2002040541A3 PCT/US2001/046055 US0146055W WO0240541A3 WO 2002040541 A3 WO2002040541 A3 WO 2002040541A3 US 0146055 W US0146055 W US 0146055W WO 0240541 A3 WO0240541 A3 WO 0240541A3
Authority
WO
WIPO (PCT)
Prior art keywords
ion channels
trich
transporters
provides
polynucleotides
Prior art date
Application number
PCT/US2001/046055
Other languages
French (fr)
Other versions
WO2002040541A2 (en
Inventor
Y Tom Tang
Henry Yue
Danniel B Nguyen
April J A Hafalia
Original Assignee
Incyte Genomics Inc
Y Tom Tang
Henry Yue
Danniel B Nguyen
April J A Hafalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Y Tom Tang, Henry Yue, Danniel B Nguyen, April J A Hafalia filed Critical Incyte Genomics Inc
Priority to US10/415,378 priority Critical patent/US20040014945A1/en
Priority to JP2002543549A priority patent/JP2004531213A/en
Priority to AU2002241569A priority patent/AU2002241569A1/en
Priority to CA002427010A priority patent/CA2427010A1/en
Priority to EP01988245A priority patent/EP1412387A2/en
Publication of WO2002040541A2 publication Critical patent/WO2002040541A2/en
Publication of WO2002040541A3 publication Critical patent/WO2002040541A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
PCT/US2001/046055 2000-10-27 2001-10-25 Transporters and ion channels WO2002040541A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US10/415,378 US20040014945A1 (en) 2001-10-25 2001-10-25 Transporters and ion channels
JP2002543549A JP2004531213A (en) 2000-10-27 2001-10-25 Transporters and ion channels
AU2002241569A AU2002241569A1 (en) 2000-10-27 2001-10-25 Transporters and ion channels
CA002427010A CA2427010A1 (en) 2000-10-27 2001-10-25 Transporters and ion channels
EP01988245A EP1412387A2 (en) 2000-10-27 2001-10-25 Transporters and ion channels

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US24398900P 2000-10-27 2000-10-27
US60/243,989 2000-10-27
US24590400P 2000-11-03 2000-11-03
US60/245,904 2000-11-03
US24767300P 2000-11-09 2000-11-09
US60/247,673 2000-11-09
US24966100P 2000-11-17 2000-11-17
US60/249,661 2000-11-17
US25223200P 2000-11-20 2000-11-20
US60/252,232 2000-11-20
US25079000P 2000-12-01 2000-12-01
US60/250,790 2000-12-01

Publications (2)

Publication Number Publication Date
WO2002040541A2 WO2002040541A2 (en) 2002-05-23
WO2002040541A3 true WO2002040541A3 (en) 2003-07-10

Family

ID=27559323

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046055 WO2002040541A2 (en) 2000-10-27 2001-10-25 Transporters and ion channels

Country Status (5)

Country Link
EP (1) EP1412387A2 (en)
JP (1) JP2004531213A (en)
AU (1) AU2002241569A1 (en)
CA (1) CA2427010A1 (en)
WO (1) WO2002040541A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2659877T3 (en) 2000-06-05 2018-03-19 The Brigham And Women's Hospital, Inc. A gene encoding a multifarm-resistant human p glycoprotein homolog on chromosome 7p15-21 and uses thereof
EP1343887A2 (en) * 2000-12-12 2003-09-17 PE Corporation (NY) Human transporter proteins, nucleic acid molecules encoding them, and uses thereof
AU2002245128A1 (en) * 2000-12-19 2002-07-30 Pe Corporation (Ny) Human transporter proteins, nucleic acid molecules encoding them, and uses thereof
US6783969B1 (en) * 2001-03-05 2004-08-31 Nuvelo, Inc. Cathepsin V-like polypeptides
EP1425377A2 (en) * 2001-04-20 2004-06-09 Neurosearch A/S Ion channel arrays
WO2003016478A2 (en) * 2001-08-20 2003-02-27 Bristol-Myers Squibb Company G-protein coupled receptor polynucleotides and methods of use thereof
WO2003025174A2 (en) * 2001-09-06 2003-03-27 Bayer Healthcare Ag Regulation of human mrp1-like protein
WO2003040184A1 (en) * 2001-11-07 2003-05-15 Takeda Chemical Industries, Ltd. Novel protein and dna thereof
AU2003269557A1 (en) * 2002-10-18 2004-05-04 Lg Life Sciences Ltd. Gene families associated with cancers
WO2005046667A2 (en) * 2003-11-07 2005-05-26 Research Foundation For Mental Hygiene, Inc. System a transport inhibitors for treating or preventing neuropsychiatric disorders
US7485468B2 (en) 2004-10-15 2009-02-03 Galapagos Bv Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
US8673268B2 (en) 2004-10-15 2014-03-18 Galapagos N.V. Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
WO2007143139A1 (en) 2006-05-31 2007-12-13 The Brigham And Women's Hospital, Inc. Abcb5 positive mesenchymal stem cells as immunomodulators
US7928202B2 (en) 2007-04-12 2011-04-19 The Brigham And Women's Hospital, Inc. Targeting ABCB5 for cancer therapy
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
ES2796111T3 (en) 2008-11-14 2020-11-25 Brigham & Womens Hospital Inc Therapeutic methods related to cancer stem cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999024836A1 (en) * 1997-11-07 1999-05-20 Human Genome Sciences, Inc. 125 human secreted proteins
WO1999047670A1 (en) * 1998-03-18 1999-09-23 Glaxo Group Limited Mammalian sodium channel proteins
WO2000008157A2 (en) * 1998-08-07 2000-02-17 Axys Pharmaceuticals, Inc. Human anion transporter genes atnov

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999024836A1 (en) * 1997-11-07 1999-05-20 Human Genome Sciences, Inc. 125 human secreted proteins
WO1999047670A1 (en) * 1998-03-18 1999-09-23 Glaxo Group Limited Mammalian sodium channel proteins
WO2000008157A2 (en) * 1998-08-07 2000-02-17 Axys Pharmaceuticals, Inc. Human anion transporter genes atnov

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
COOPER E C ET AL: "Ion channel genes and human neurological disease: Recent progress, prospects, and challenges", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 96, no. 9, 27 April 1999 (1999-04-27), pages 4759 - 4766, XP002174532, ISSN: 0027-8424 *
MARICQ A V ET AL: "Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel", SCIENCE, AAAS. LANCASTER, PA, US, vol. 254, 18 October 1991 (1991-10-18), pages 432 - 437, XP002157173, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
CA2427010A1 (en) 2002-05-23
EP1412387A2 (en) 2004-04-28
WO2002040541A2 (en) 2002-05-23
AU2002241569A1 (en) 2002-05-27
JP2004531213A (en) 2004-10-14

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