WO2002039996A3 - Combined therapy against tumors comprising estramustine phosphate and lhrh agonists or antagonists - Google Patents

Combined therapy against tumors comprising estramustine phosphate and lhrh agonists or antagonists Download PDF

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Publication number
WO2002039996A3
WO2002039996A3 PCT/US2001/044161 US0144161W WO0239996A3 WO 2002039996 A3 WO2002039996 A3 WO 2002039996A3 US 0144161 W US0144161 W US 0144161W WO 0239996 A3 WO0239996 A3 WO 0239996A3
Authority
WO
WIPO (PCT)
Prior art keywords
antagonists
estramustine phosphate
combined therapy
against tumors
therapy against
Prior art date
Application number
PCT/US2001/044161
Other languages
French (fr)
Other versions
WO2002039996A2 (en
Inventor
Jeffrey H Buchalter
Ivan D Horak
Original Assignee
Pharmacia & Up John Company
Jeffrey H Buchalter
Ivan D Horak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Up John Company, Jeffrey H Buchalter, Ivan D Horak filed Critical Pharmacia & Up John Company
Priority to AU2002228648A priority Critical patent/AU2002228648A1/en
Publication of WO2002039996A2 publication Critical patent/WO2002039996A2/en
Publication of WO2002039996A3 publication Critical patent/WO2002039996A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method for treating tumors in a mammal, including humans, in need of such a treatment including administering simultaneously, separately or sequentially to said mammal estramustine phosphate and a LHRH agonist or antagonist, in amounts sufficient to achieve a therapeutically useful effect.
PCT/US2001/044161 2000-11-16 2001-11-06 Combined therapy against tumors comprising estramustine phosphate and lhrh agonists or antagonists WO2002039996A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002228648A AU2002228648A1 (en) 2000-11-16 2001-11-06 Combined therapy against tumors comprising estramustine phosphate and lhrh agonists or antagonists

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71460600A 2000-11-16 2000-11-16
US09/714,606 2000-11-16

Publications (2)

Publication Number Publication Date
WO2002039996A2 WO2002039996A2 (en) 2002-05-23
WO2002039996A3 true WO2002039996A3 (en) 2003-03-20

Family

ID=24870732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/044161 WO2002039996A2 (en) 2000-11-16 2001-11-06 Combined therapy against tumors comprising estramustine phosphate and lhrh agonists or antagonists

Country Status (2)

Country Link
AU (1) AU2002228648A1 (en)
WO (1) WO2002039996A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8841342B2 (en) 2002-08-09 2014-09-23 Vital Health Sciences Pty. Ltd. Carrier
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US9314527B2 (en) 2010-03-30 2016-04-19 Phosphagenics Limited Transdermal delivery patch
US9561243B2 (en) 2011-03-15 2017-02-07 Phosphagenics Limited Composition comprising non-neutralised tocol phosphate and a vitamin A compound

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4905624B2 (en) * 2003-10-31 2012-03-28 学校法人 久留米大学 Combination therapy of peptide vaccine administration and estramustine treatment
AU2003280688A1 (en) * 2003-10-31 2005-05-19 Kurume University Combination therapy of peptide vaccination and estramustine treatment
AU2011213557B2 (en) 2010-02-05 2015-05-07 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
KR102647670B1 (en) 2016-12-21 2024-03-15 아베초 바이오테크놀로지 리미티드 method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998029123A1 (en) * 1996-12-30 1998-07-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin d analogues
WO1998029105A2 (en) * 1996-12-30 1998-07-09 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin d formulations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
WO1998029123A1 (en) * 1996-12-30 1998-07-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin d analogues
WO1998029105A2 (en) * 1996-12-30 1998-07-09 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin d formulations

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ACTA UROLOGICA JAPONICA, vol. 41, no. 9, 1995, pages 683 - 685, ISSN: 0018-1994 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, MIYAJIMA AKIRA ET AL: "A case of huge prostate cancer.", XP002224436, Database accession no. PREV199698596655 *
SHIINA H ET AL: "IMMUNOHISTOCHEMICAL ANALYSIS OF ESTRAMUSTINE BINDING PROTEIN WITH PARTICULAR REFERENCE TO PROLIFERATIVE ACTIVITY IN HUMAN PROSTATIC CARCINOMA", PROSTATE, WILEY-LISS, NEW YORK, NY, US, vol. 32, no. 1, 15 June 1997 (1997-06-15), pages 49 - 58, XP001079665, ISSN: 0270-4137 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8841342B2 (en) 2002-08-09 2014-09-23 Vital Health Sciences Pty. Ltd. Carrier
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US9314527B2 (en) 2010-03-30 2016-04-19 Phosphagenics Limited Transdermal delivery patch
US9561243B2 (en) 2011-03-15 2017-02-07 Phosphagenics Limited Composition comprising non-neutralised tocol phosphate and a vitamin A compound

Also Published As

Publication number Publication date
AU2002228648A1 (en) 2002-05-27
WO2002039996A2 (en) 2002-05-23

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