WO2002031204A3 - Assay to detect integration of a retrovirus polynucleotide into a target nucleic acid - Google Patents
Assay to detect integration of a retrovirus polynucleotide into a target nucleic acid Download PDFInfo
- Publication number
- WO2002031204A3 WO2002031204A3 PCT/US2001/031807 US0131807W WO0231204A3 WO 2002031204 A3 WO2002031204 A3 WO 2002031204A3 US 0131807 W US0131807 W US 0131807W WO 0231204 A3 WO0231204 A3 WO 0231204A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acid
- target nucleic
- assay
- integration
- retrovirus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/507—Recombinase
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- AIDS & HIV (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002424998A CA2424998A1 (en) | 2000-10-10 | 2001-10-09 | Nucleic acid integration assay |
AU2001296814A AU2001296814A1 (en) | 2000-10-10 | 2001-10-09 | Assay to detect integration of a retrovirus polynucleotide into a target nucleic acid |
EP01977718A EP1349959A2 (en) | 2000-10-10 | 2001-10-09 | Assay to detect integration of a retrovirus polynucleotide into a target nucleic acid |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23931300P | 2000-10-10 | 2000-10-10 | |
US60/239,313 | 2000-10-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002031204A2 WO2002031204A2 (en) | 2002-04-18 |
WO2002031204A3 true WO2002031204A3 (en) | 2003-08-07 |
Family
ID=22901615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/031807 WO2002031204A2 (en) | 2000-10-10 | 2001-10-09 | Assay to detect integration of a retrovirus polynucleotide into a target nucleic acid |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1349959A2 (en) |
AU (1) | AU2001296814A1 (en) |
CA (1) | CA2424998A1 (en) |
WO (1) | WO2002031204A2 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992020813A1 (en) * | 1991-05-17 | 1992-11-26 | Dana Farber Cancer Institute | Assays for factors affecting circularization of dna, assays for factors affecting dna integration, factors, and uses thereof |
WO1999047660A1 (en) * | 1998-03-18 | 1999-09-23 | The Salk Institute For Biological Studies | Retroviral packaging cell line |
-
2001
- 2001-10-09 WO PCT/US2001/031807 patent/WO2002031204A2/en not_active Application Discontinuation
- 2001-10-09 AU AU2001296814A patent/AU2001296814A1/en not_active Abandoned
- 2001-10-09 EP EP01977718A patent/EP1349959A2/en not_active Withdrawn
- 2001-10-09 CA CA002424998A patent/CA2424998A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992020813A1 (en) * | 1991-05-17 | 1992-11-26 | Dana Farber Cancer Institute | Assays for factors affecting circularization of dna, assays for factors affecting dna integration, factors, and uses thereof |
WO1999047660A1 (en) * | 1998-03-18 | 1999-09-23 | The Salk Institute For Biological Studies | Retroviral packaging cell line |
Non-Patent Citations (4)
Title |
---|
HANSEN M S ET AL: "Integration complexes derived from HIV vectors for rapid assays in vitro.", NATURE BIOTECHNOLOGY. UNITED STATES JUN 1999, vol. 17, no. 6, June 1999 (1999-06-01), pages 578 - 582, XP001097540, ISSN: 1087-0156 * |
KORNBLUTH R S ET AL: "Quantitative analysis of HIV-1 pre-integration complexes using an in vitro, PCR-based integration assay.", FASEB JOURNAL, vol. 10, no. 6, 1996, Joint Meeting of the American Society for Biochemistry and Molecular Biology, the American Society for Investigative Pathology and the American Association of Immunologists;New Orleans, Louisiana, USA, pages A1061, XP009003098, ISSN: 0892-6638 * |
LU F ET AL: "Tn916 target DNA sequences bind the C-terminal domain of integrase protein with different affinities that correlate with transposon insertion frequency.", JOURNAL OF BACTERIOLOGY. UNITED STATES APR 1995, vol. 177, no. 8, April 1995 (1995-04-01), pages 1938 - 1946, XP002226005, ISSN: 0021-9193 * |
PRUSS D ET AL: "Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. UNITED STATES 21 JUN 1994, vol. 91, no. 13, 21 June 1994 (1994-06-21), pages 5913 - 5917, XP002226004, ISSN: 0027-8424 * |
Also Published As
Publication number | Publication date |
---|---|
AU2001296814A1 (en) | 2002-04-22 |
CA2424998A1 (en) | 2002-04-18 |
WO2002031204A2 (en) | 2002-04-18 |
EP1349959A2 (en) | 2003-10-08 |
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