WO2002029048A3 - Regulation of human sodium-dependent neurotransmitter transporter - Google Patents

Regulation of human sodium-dependent neurotransmitter transporter Download PDF

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Publication number
WO2002029048A3
WO2002029048A3 PCT/EP2001/011440 EP0111440W WO0229048A3 WO 2002029048 A3 WO2002029048 A3 WO 2002029048A3 EP 0111440 W EP0111440 W EP 0111440W WO 0229048 A3 WO0229048 A3 WO 0229048A3
Authority
WO
WIPO (PCT)
Prior art keywords
neurotransmitter transporter
human sodium
regulation
dependent neurotransmitter
dependent
Prior art date
Application number
PCT/EP2001/011440
Other languages
French (fr)
Other versions
WO2002029048A2 (en
Inventor
Rainer H Kohler
Original Assignee
Bayer Ag
Rainer H Kohler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Rainer H Kohler filed Critical Bayer Ag
Priority to AU2001295590A priority Critical patent/AU2001295590A1/en
Publication of WO2002029048A2 publication Critical patent/WO2002029048A2/en
Publication of WO2002029048A3 publication Critical patent/WO2002029048A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

Reagents which regulate human sodium-dependent neurotransmitter transporter and reagents which bind to human sodium-dependent neurotransmitter transporter gene products can play a role in preventing, ameliorating, or correcting central and peripheral nervous system diseases.
PCT/EP2001/011440 2000-10-05 2001-10-04 Regulation of human sodium-dependent neurotransmitter transporter WO2002029048A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001295590A AU2001295590A1 (en) 2000-10-05 2001-10-04 Regulation of human sodium-dependent neurotransmitter transporter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23768900P 2000-10-05 2000-10-05
US60/237,689 2000-10-05

Publications (2)

Publication Number Publication Date
WO2002029048A2 WO2002029048A2 (en) 2002-04-11
WO2002029048A3 true WO2002029048A3 (en) 2002-11-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011440 WO2002029048A2 (en) 2000-10-05 2001-10-04 Regulation of human sodium-dependent neurotransmitter transporter

Country Status (2)

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AU (1) AU2001295590A1 (en)
WO (1) WO2002029048A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995031539A1 (en) * 1994-05-16 1995-11-23 Human Genome Sciences, Inc. Neurotransmitter transporter
WO2001019854A2 (en) * 1999-09-15 2001-03-22 Smithkline Beecham P.L.C. Neurotransmitter transporter
WO2001064875A2 (en) * 2000-02-29 2001-09-07 Millennium Pharmaceuticals, Inc. Human transporter genes and proteins encoded thereby
WO2002020757A2 (en) * 2000-09-05 2002-03-14 Applera Corporation Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995031539A1 (en) * 1994-05-16 1995-11-23 Human Genome Sciences, Inc. Neurotransmitter transporter
WO2001019854A2 (en) * 1999-09-15 2001-03-22 Smithkline Beecham P.L.C. Neurotransmitter transporter
WO2001064875A2 (en) * 2000-02-29 2001-09-07 Millennium Pharmaceuticals, Inc. Human transporter genes and proteins encoded thereby
WO2002020757A2 (en) * 2000-09-05 2002-03-14 Applera Corporation Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 22 February 2000 (2000-02-22), "Homo sapiens cDNA FLJ10316 fis, clone NT2RM2000422, highly similar to sodium- and chloride-dependent transporter NTT73", XP002203924, Database accession no. AK001178 *
DATABASE EMBL [online] 29 April 1999 (1999-04-29), "Bos taurus bv7-3 mRNA for orphan transporter short splicing variant, complete cds.", XP002203925, Database accession no. AB020854 *
UHL G.R. ET AL.: "Neurotransmitter transporter family cDNAs in a rat midbrain library: ' orphan transporters ' suggest sizable structural variations", MOLECULAR BRAIN RESEARCH, vol. 16, no. 3/4, 1992, pages 353 - 359, XP000986881, ISSN: 0169-328X *

Also Published As

Publication number Publication date
WO2002029048A2 (en) 2002-04-11
AU2001295590A1 (en) 2002-04-15

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