WO2002024737A8 - Sequences nucleotidiques codant pour le gene dps - Google Patents

Sequences nucleotidiques codant pour le gene dps

Info

Publication number
WO2002024737A8
WO2002024737A8 PCT/EP2001/010523 EP0110523W WO0224737A8 WO 2002024737 A8 WO2002024737 A8 WO 2002024737A8 EP 0110523 W EP0110523 W EP 0110523W WO 0224737 A8 WO0224737 A8 WO 0224737A8
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotide
glutamicum
code
amino acid
nucleotide sequences
Prior art date
Application number
PCT/EP2001/010523
Other languages
English (en)
Other versions
WO2002024737A1 (fr
Inventor
Brigitte Bathe
Caroline Kreutzer
Mechthild Rieping
Achim Marx
Mike Farwick
Walter Pfefferle
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Priority to EP01980373A priority Critical patent/EP1319019A1/fr
Priority to AU2002212232A priority patent/AU2002212232A1/en
Publication of WO2002024737A1 publication Critical patent/WO2002024737A1/fr
Publication of WO2002024737A8 publication Critical patent/WO2002024737A8/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un polynucléotide isolé contenant une séquence polynucléotidique sélectionnée dans le groupe constitué par a) un polynucléotide identique, au moins à 70 %, à un polynucléotide codant pour un polypeptide qui contient une séquence d'acides aminés de SEQ ID N° 2, b) un polynucléotide codant pour un polypeptide qui contient une séquence d'acides aminés identique, à au moins 70 %, à la séquence d'acides aminés de SEQ ID N° 2, c) un polynucléotide complémentaire aux polynucléotides a) ou b), et d) un polynucléotide contenant au moins 15 nucléotides successifs de la séquence polynucléotidique de a), b) ou c). Cette invention concerne également un procédé pour la préparation fermentative d'acides L-aminés, utilisant des bactéries corynéformes présentant au moins le gène dps sous forme évoluée, ainsi que l'utilisation en tant que sondes d'hybridation de polynucléotides contenant les séquences selon l'invention.
PCT/EP2001/010523 2000-09-20 2001-09-12 Sequences nucleotidiques codant pour le gene dps WO2002024737A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01980373A EP1319019A1 (fr) 2000-09-20 2001-09-12 Sequences nucleotidiques codant pour le gene dps
AU2002212232A AU2002212232A1 (en) 2000-09-20 2001-09-12 Nucleotide sequences which code for the dps gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10046623A DE10046623A1 (de) 2000-09-20 2000-09-20 Neue für das dps-Gen kodierende Nukleotidsequenzen
DE10046623.0 2000-09-20

Publications (2)

Publication Number Publication Date
WO2002024737A1 WO2002024737A1 (fr) 2002-03-28
WO2002024737A8 true WO2002024737A8 (fr) 2002-06-06

Family

ID=7656987

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/010523 WO2002024737A1 (fr) 2000-09-20 2001-09-12 Sequences nucleotidiques codant pour le gene dps

Country Status (5)

Country Link
US (1) US20020106760A1 (fr)
EP (1) EP1319019A1 (fr)
AU (1) AU2002212232A1 (fr)
DE (1) DE10046623A1 (fr)
WO (1) WO2002024737A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10132945A1 (de) * 2001-07-06 2003-01-16 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
ATE449167T1 (de) * 2001-07-06 2009-12-15 Evonik Degussa Gmbh Verfahren zur herstellung von l-aminosäuren mit stämmen der familie enterobacteriaceae
KR100541848B1 (ko) * 2003-04-03 2006-01-10 학교법인 포항공과대학교 비특이적 DNA 결합단백질 dps와 목적 단백질을 대장균에서 동시에 발현시킴으로써 목적 단백질을생산하는 방법, 그에 사용되는 벡터 및 형질전환된 대장균
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2169225T3 (es) * 1995-02-20 2002-07-01 Ajinomoto Kk Micro-organismo tolerante del estres y procedimiento de produccion de producto de fermentacion.
DE19855313A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド

Also Published As

Publication number Publication date
DE10046623A1 (de) 2002-03-28
US20020106760A1 (en) 2002-08-08
WO2002024737A1 (fr) 2002-03-28
AU2002212232A1 (en) 2002-04-02
EP1319019A1 (fr) 2003-06-18

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