WO2002018543A3 - Fermentation process for the preparation of l-threonine - Google Patents

Fermentation process for the preparation of l-threonine Download PDF

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Publication number
WO2002018543A3
WO2002018543A3 PCT/EP2001/008603 EP0108603W WO0218543A3 WO 2002018543 A3 WO2002018543 A3 WO 2002018543A3 EP 0108603 W EP0108603 W EP 0108603W WO 0218543 A3 WO0218543 A3 WO 0218543A3
Authority
WO
WIPO (PCT)
Prior art keywords
threonine
preparation
fermentation process
inoculation
cultured
Prior art date
Application number
PCT/EP2001/008603
Other languages
French (fr)
Other versions
WO2002018543A2 (en
Inventor
Thomas Hermann
Mechthild Rieping
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10103778A external-priority patent/DE10103778A1/en
Application filed by Degussa filed Critical Degussa
Priority to AU2002220542A priority Critical patent/AU2002220542A1/en
Priority to KR10-2003-7002959A priority patent/KR20030033039A/en
Priority to EP01984568A priority patent/EP1313838A2/en
Priority to MXPA03000585A priority patent/MXPA03000585A/en
Priority to CNB018149669A priority patent/CN1318574C/en
Publication of WO2002018543A2 publication Critical patent/WO2002018543A2/en
Publication of WO2002018543A3 publication Critical patent/WO2002018543A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to a process for the fermentative preparation of L-threonine in which an L-threonine-producing microorganism of the Enterobacteriaceae family is cultured by the feed process, and a portion of the fermentation broth is then separated off in order to be utilized for inoculation of further media.
PCT/EP2001/008603 2000-08-31 2001-07-25 Fermentation process for the preparation of l-threonine WO2002018543A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2002220542A AU2002220542A1 (en) 2000-08-31 2001-07-25 Fermentation process for the preparation of l-threonine
KR10-2003-7002959A KR20030033039A (en) 2000-08-31 2001-07-25 Fermentation process for the preparation of L-threonine
EP01984568A EP1313838A2 (en) 2000-08-31 2001-07-25 Fermentation process for the preparation of l-threonine
MXPA03000585A MXPA03000585A (en) 2000-08-31 2001-07-25 Fermentation process for the preparation of l-threonine.
CNB018149669A CN1318574C (en) 2000-08-31 2001-07-25 Fermentation process for the preparation of L-threonine

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10042745.6 2000-08-31
DE10042745 2000-08-31
DE10103778A DE10103778A1 (en) 2000-08-31 2001-01-27 New fermentation process for the production of L-threonine
DE10103778.3 2001-01-27

Publications (2)

Publication Number Publication Date
WO2002018543A2 WO2002018543A2 (en) 2002-03-07
WO2002018543A3 true WO2002018543A3 (en) 2003-01-03

Family

ID=26006864

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/008603 WO2002018543A2 (en) 2000-08-31 2001-07-25 Fermentation process for the preparation of l-threonine

Country Status (5)

Country Link
EP (1) EP1313838A2 (en)
CN (1) CN1318574C (en)
AU (1) AU2002220542A1 (en)
MX (1) MXPA03000585A (en)
WO (1) WO2002018543A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100837842B1 (en) * 2006-08-10 2008-06-13 씨제이제일제당 (주) - - A microorganism whose activity of Aspartate Semialdehyde Dehydrogenase is enhanced and the process for producing L-threonine using the microorganism
FI20065762A0 (en) * 2006-11-30 2006-11-30 Oulun Yliopisto Procedure for controlling growth in cell culture
DE102007051024A1 (en) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Process for the preparation of L-amino acids using strains of the family Enterobacteriaceae
EP1975241A1 (en) 2007-03-29 2008-10-01 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family
DE102007044134A1 (en) 2007-09-15 2009-03-19 Evonik Degussa Gmbh Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
DE102007052270A1 (en) 2007-11-02 2009-05-07 Evonik Degussa Gmbh Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
EP2060636A1 (en) 2007-11-14 2009-05-20 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family
EP2098597A1 (en) 2008-03-04 2009-09-09 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family
DE102008002309A1 (en) 2008-06-09 2009-12-10 Evonik Degussa Gmbh Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
DE102008040352A1 (en) 2008-07-11 2010-01-14 Evonik Degussa Gmbh Process for the preparation of L-tryptophan using improved strains of the family Enterobacteriaceae
DE102008044768A1 (en) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Process for the preparation of organochemical compounds using improved strains of the family Enterobacteriaceae
EP3385275B1 (en) 2017-04-07 2019-10-23 Evonik Degussa GmbH Method for producing aromatic l-amino acids using improved strains of the enterobacteriaceae family
EP3608409A1 (en) 2018-08-09 2020-02-12 Evonik Operations GmbH Process for preparing l amino acids using improved strains of the enterobacteriaceae family
US11053526B2 (en) 2018-08-09 2021-07-06 Evonik Operations Gmbh Process for preparing L amino acids using improved strains of the enterobacteriaceae family
CN109554322B (en) * 2018-12-03 2020-08-04 江南大学 Recombinant Escherichia coli with high L-threonine yield and construction method thereof
EP3677594A1 (en) 2019-01-07 2020-07-08 Evonik Operations GmbH Method for producing l-tryptophan using improved strains of the enterobacteriaceae family

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1009370A (en) * 1962-12-18 1965-11-10 Ajinomoto I I A process for the production of 1-glutamic acid by fermentation
EP0593792A1 (en) * 1992-10-14 1994-04-27 Ajinomoto Co., Inc. Novel L-threonine-producing microbacteria and a method for the production of L-threonine
EP1085091A1 (en) * 1999-09-01 2001-03-21 Degussa-Hüls Aktiengesellschaft Nucleotide sequences coding for thrE-gene and process for the fermentative preparation of L-threonine using coryneform bacteria
WO2002026993A1 (en) * 2000-09-28 2002-04-04 Archer-Daniels-Midland Company Escherichia coli strains which over-produce l-threonine and processes for the production of l-threonine by fermentation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004636A1 (en) * 1988-10-25 1990-05-03 Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) Strain of bacteria escherichia coli, producer of l-threonine
US5939307A (en) * 1996-07-30 1999-08-17 The Archer-Daniels-Midland Company Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1009370A (en) * 1962-12-18 1965-11-10 Ajinomoto I I A process for the production of 1-glutamic acid by fermentation
EP0593792A1 (en) * 1992-10-14 1994-04-27 Ajinomoto Co., Inc. Novel L-threonine-producing microbacteria and a method for the production of L-threonine
EP1085091A1 (en) * 1999-09-01 2001-03-21 Degussa-Hüls Aktiengesellschaft Nucleotide sequences coding for thrE-gene and process for the fermentative preparation of L-threonine using coryneform bacteria
WO2002026993A1 (en) * 2000-09-28 2002-04-04 Archer-Daniels-Midland Company Escherichia coli strains which over-produce l-threonine and processes for the production of l-threonine by fermentation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1313838A2 *

Also Published As

Publication number Publication date
CN1318574C (en) 2007-05-30
WO2002018543A2 (en) 2002-03-07
MXPA03000585A (en) 2003-06-06
AU2002220542A1 (en) 2002-03-13
EP1313838A2 (en) 2003-05-28
CN1630711A (en) 2005-06-22

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