WO2002016397A3 - Haplotypes of the lipg gene - Google Patents

Haplotypes of the lipg gene Download PDF

Info

Publication number
WO2002016397A3
WO2002016397A3 PCT/US2001/026639 US0126639W WO0216397A3 WO 2002016397 A3 WO2002016397 A3 WO 2002016397A3 US 0126639 W US0126639 W US 0126639W WO 0216397 A3 WO0216397 A3 WO 0216397A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
lipg
gene
disclosed
lipg gene
Prior art date
Application number
PCT/US2001/026639
Other languages
French (fr)
Other versions
WO2002016397A2 (en
Inventor
Amy Duda
Amir Kazemi
Stefanie E Kliem
Chad Messer
Original Assignee
Genaissance Pharmaceuticals
Amy Duda
Amir Kazemi
Stefanie E Kliem
Chad Messer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Amy Duda, Amir Kazemi, Stefanie E Kliem, Chad Messer filed Critical Genaissance Pharmaceuticals
Priority to AU2001288422A priority Critical patent/AU2001288422A1/en
Publication of WO2002016397A2 publication Critical patent/WO2002016397A2/en
Publication of WO2002016397A3 publication Critical patent/WO2002016397A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Novel genetic variants of the Lipase, Endothelial (LIPG) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the LIPG gene. Compositions and methods for haplotyping and/or genotyping the LIPG gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
PCT/US2001/026639 2000-08-25 2001-08-17 Haplotypes of the lipg gene WO2002016397A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001288422A AU2001288422A1 (en) 2000-08-25 2001-08-17 Haplotypes of the lipg gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22782500P 2000-08-25 2000-08-25
US60/227,825 2000-08-25

Publications (2)

Publication Number Publication Date
WO2002016397A2 WO2002016397A2 (en) 2002-02-28
WO2002016397A3 true WO2002016397A3 (en) 2002-08-08

Family

ID=22854617

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/026639 WO2002016397A2 (en) 2000-08-25 2001-08-17 Haplotypes of the lipg gene

Country Status (2)

Country Link
AU (1) AU2001288422A1 (en)
WO (1) WO2002016397A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521301A (en) * 1988-12-12 1996-05-28 City Of Hope Genotyping of multiple allele systems
US5851762A (en) * 1990-07-11 1998-12-22 Gene Type Ag Genomic mapping method by direct haplotyping using intron sequence analysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521301A (en) * 1988-12-12 1996-05-28 City Of Hope Genotyping of multiple allele systems
US5851762A (en) * 1990-07-11 1998-12-22 Gene Type Ag Genomic mapping method by direct haplotyping using intron sequence analysis

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] NATIONAL INSTITUTE FOR BIOTECHNOLOGY INFORMATION, NATIONAL INSTITUTES OF HEALTH (BETHESDA, MD, USA); 30 May 2000 (2000-05-30), HATTORI ET AL.: "Homo sapiens 190,119 genomic DNA of 18q12", Database accession no. (AP001814) *
HIRATA ET AL.: "Cloning of a unique lipase from endothelial cells extends the lipase gene family", J. BIOL. CHEM., vol. 274, no. 20, 14 May 1999 (1999-05-14), pages 14170 - 14175 *
JAYE ET AL.: "A novel endothelial derived lipase that modulates HDL metabolism", NATURE GENETICS, vol. 21, no. 4, April 1999 (1999-04-01), pages 424 - 428 *
ROSSI ET AL.: "The nematode resistance gene Mi of tomato confers resistance against the potato aphid", PROC. NATL. ACAD. SCI. USA, vol. 95, August 1998 (1998-08-01), pages 9750 - 9754 *

Also Published As

Publication number Publication date
AU2001288422A1 (en) 2002-03-04
WO2002016397A2 (en) 2002-02-28

Similar Documents

Publication Publication Date Title
WO2001079234A3 (en) Haplotypes of the apoe gene
WO2002018414A3 (en) Haplotypes of the bf gene
WO2002008425A3 (en) Haplotypes of the adrb3 gene
WO2002090512A3 (en) Haplotypes of the nnmt gene
WO2002040502A3 (en) Haplotypes of the lipe gene
WO2002016397A3 (en) Haplotypes of the lipg gene
WO2002010454A3 (en) Haplotypes of the alas2 gene
WO2001090127A3 (en) Haplotypes of the hoxd3 gene
WO2002032928A3 (en) Haplotypes of the hrh1 gene
WO2002012562A3 (en) Haplotypes of the pla2g1b gene
WO2001087909A3 (en) Haplotypes of the aanat gene
WO2002042320A3 (en) Haplotypes of the gsr gene
WO2002040503A3 (en) Haplotypes of the plau gene
WO2002050098A3 (en) Haplotypes of the prlr gene
WO2002012499A3 (en) Haplotypes of the ntf3 gene
WO2002090378A3 (en) Haplotypes of the ces2 gene
WO2002044201A3 (en) Haplotypes of the sah gene
WO2002030950A3 (en) Haplotypes of the fy gene
WO2001090118A3 (en) Haplotypes of the edn2 gene
WO2002032924A3 (en) Haplotypes of the chrm5 gene
WO2002010190A3 (en) Haplotypes of the il12b gene
WO2001087907A3 (en) Haplotypes of the osm gene
WO2002038586A3 (en) Haplotypes of the il6 gene
WO2002016399A3 (en) Haplotypes of the tacr1 gene
WO2001094362A3 (en) Haplotypes of the acp2 gene

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WPC Withdrawal of priority claims after completion of the technical preparations for international publication

Ref country code: WO

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP