WO2002012478A3 - Methyl-d-erythritol phosphate pathway genes - Google Patents

Methyl-d-erythritol phosphate pathway genes Download PDF

Info

Publication number
WO2002012478A3
WO2002012478A3 PCT/US2001/024335 US0124335W WO0212478A3 WO 2002012478 A3 WO2002012478 A3 WO 2002012478A3 US 0124335 W US0124335 W US 0124335W WO 0212478 A3 WO0212478 A3 WO 0212478A3
Authority
WO
WIPO (PCT)
Prior art keywords
methyl
pathway genes
phosphate pathway
transgenic plants
erythritol phosphate
Prior art date
Application number
PCT/US2001/024335
Other languages
French (fr)
Other versions
WO2002012478A8 (en
WO2002012478A2 (en
Inventor
Albert Boronat
Narciso Campos
Manuel Rodriguez-Concepcion
Michel Rohmer
Myriam Seemann
Henry E Valentin
Tyamagondlu V Venkatesh
Mylavarapu Venkatramesh
Original Assignee
Monsanto Technology Llc
Albert Boronat
Narciso Campos
Manuel Rodriguez-Concepcion
Michel Rohmer
Myriam Seemann
Henry E Valentin
Tyamagondlu V Venkatesh
Mylavarapu Venkatramesh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc, Albert Boronat, Narciso Campos, Manuel Rodriguez-Concepcion, Michel Rohmer, Myriam Seemann, Henry E Valentin, Tyamagondlu V Venkatesh, Mylavarapu Venkatramesh filed Critical Monsanto Technology Llc
Priority to AU9052201A priority Critical patent/AU9052201A/en
Priority to AU2001290522A priority patent/AU2001290522B2/en
Priority to CA2418436A priority patent/CA2418436C/en
Priority to AT01970529T priority patent/ATE447017T1/en
Priority to DE60140312T priority patent/DE60140312D1/en
Priority to EP01970529A priority patent/EP1356033B1/en
Publication of WO2002012478A2 publication Critical patent/WO2002012478A2/en
Publication of WO2002012478A8 publication Critical patent/WO2002012478A8/en
Publication of WO2002012478A3 publication Critical patent/WO2002012478A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/825—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention provides and includes nucleic acids, proteins and antibodies associated with novel genes in the MEP pathway. The invention further encompasses methods utilizing such molecules, for example in gene isolation, gene analysis and the production of transgenic plants. The present invention also includes transgenic plants modified to express proteins associated with the MEP pathway.
PCT/US2001/024335 2000-08-07 2001-08-06 Methyl-d-erythritol phosphate pathway genes WO2002012478A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU9052201A AU9052201A (en) 2000-08-07 2001-08-06 Methyl-d-erythritol phosphate pathway genes
AU2001290522A AU2001290522B2 (en) 2000-08-07 2001-08-06 Methyl-D-erythritol phosphate pathway genes
CA2418436A CA2418436C (en) 2000-08-07 2001-08-06 Methyl-d-erythritol phosphate pathway genes
AT01970529T ATE447017T1 (en) 2000-08-07 2001-08-06 GENES INVOLVED IN THE METHYL-D-ERYTHRIOL PHOSPHATE PATHWAY
DE60140312T DE60140312D1 (en) 2000-08-07 2001-08-06 Am methyl-d-erythriol phosphat reaktionsweg beteiligte gene
EP01970529A EP1356033B1 (en) 2000-08-07 2001-08-06 Methyl-d-erythritol phosphate pathway genes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22348300P 2000-08-07 2000-08-07
US60/223,483 2000-08-07

Publications (3)

Publication Number Publication Date
WO2002012478A2 WO2002012478A2 (en) 2002-02-14
WO2002012478A8 WO2002012478A8 (en) 2002-07-04
WO2002012478A3 true WO2002012478A3 (en) 2003-07-03

Family

ID=22836696

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/024335 WO2002012478A2 (en) 2000-08-07 2001-08-06 Methyl-d-erythritol phosphate pathway genes

Country Status (8)

Country Link
US (3) US6841717B2 (en)
EP (1) EP1356033B1 (en)
AR (1) AR030124A1 (en)
AT (1) ATE447017T1 (en)
AU (2) AU2001290522B2 (en)
CA (1) CA2418436C (en)
DE (1) DE60140312D1 (en)
WO (1) WO2002012478A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002541851A (en) * 1999-04-15 2002-12-10 カルジーン エルエルシー Nucleic acid sequence of protein involved in isoprenoid synthesis
DE60036477T2 (en) 1999-08-04 2008-06-12 Bacher, Adelbert, Prof. Dr.med. Dr.rer.nat. ISOPRENOID BIOSYNTHESIS
US6872815B1 (en) * 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
DE10027821A1 (en) 2000-06-05 2001-12-06 Adelbert Bacher New intermediate in isoprenoid biosynthesis, useful in screening for potential herbicides, comprises mutant encoding-enzymes sequences for imparting herbicide resistance
AU2001290522B2 (en) 2000-08-07 2006-11-30 Monsanto Technology Llc Methyl-D-erythritol phosphate pathway genes
DE10201458A1 (en) * 2001-04-11 2002-10-17 Adelbert Bacher New proteins involved in isoprenoid biosynthesis, useful in screening for inhibitors, also new intermediates, potential therapeutic agents, nucleic acids and antibodies
EP1950305A1 (en) * 2001-05-09 2008-07-30 Monsanto Technology, LLC Tyr a genes and uses thereof
ES2318004T3 (en) * 2001-05-09 2009-05-01 Monsanto Technology Llc TYRA GENES AND USES OF THE SAME.
US7161061B2 (en) * 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
PT1408984E (en) 2001-07-20 2008-12-26 Bioagency Ag Organo-phosphorous compounds for activating gamma/delta t cells
WO2003016482A2 (en) * 2001-08-17 2003-02-27 Monsanto Technology Llc Methyltransferase genes and uses thereof
DE60235252D1 (en) * 2001-10-25 2010-03-18 Monsanto Technology Llc AROMATIC METHYLTRANSFERASES AND THEIR USE
BR0308740A (en) * 2002-03-19 2007-01-09 Monsanto Technology Llc homogenous prenyl transferase ("hpt") nucleic acids and polypeptides, and their use
AU2003268083A1 (en) * 2002-08-05 2004-02-23 Monsanto Technology, Llc Tocopherol biosynthesis related genes and uses thereof
WO2004044205A1 (en) * 2002-11-11 2004-05-27 Korea Chungang Educational Foundation Plant seed-specific expression promoter derived from sesame and seed-specific expression vector comprising the promoter
US20050272116A1 (en) * 2004-06-04 2005-12-08 Clemson University Polymer substrate for recombinant protein purification and environmental remediation
ES2267390B1 (en) * 2005-06-16 2008-03-16 Universidad Politecnica De Valencia INSULATION AND CHARACTERIZATION OF MUTANT CSB3-1 OF THALIAN ARABIDOPSIS, AND ITS USE AS A REGULATOR OF THE RESISTANCE IN PLANTS TO DISEASES PRODUCED BY BIOTROPHIC PATHOGENS.
EP1904637B1 (en) 2005-07-01 2010-10-27 University of Kentucky Research Foundation Transformed plants accumulating mono- and/or sesquiterpenes
KR20130140114A (en) 2011-02-14 2013-12-23 질레코 인코포레이티드 Processing biomass
CA3080669A1 (en) 2017-10-27 2019-05-02 Xyleco, Inc. Processing biomass

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058649A1 (en) * 1998-05-13 1999-11-18 University Of Maryland Methods of modifying the production of isopentenyl pyrophosphate, dimethylallyl pyrophosphate and/or isoprenoids
DE19835219A1 (en) * 1998-08-05 2000-02-10 Basf Ag Use of 1-deoxy-D-xylulose-5-phosphate synthase DNA to produce plants with increased tocopherol, vitamin K, chlorophyll and/or carotenoid content
WO2000008169A1 (en) * 1998-08-05 2000-02-17 Sungene Gmbh & Co.Kgaa Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants
WO2000017233A2 (en) * 1998-09-22 2000-03-30 Jomaa Pharmaka Gmbh Genes of the 1-desoxy-d-xylulose biosynthetic pathway

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB560529A (en) 1942-04-16 1944-04-07 Distillation Products Inc Preparation of stabilized edible substances
US4727219A (en) 1986-11-28 1988-02-23 Agracetus Genic male-sterile maize using a linked marker gene
US5922602A (en) 1988-02-26 1999-07-13 Biosource Technologies, Inc. Cytoplasmic inhibition of gene expression
US5693507A (en) 1988-09-26 1997-12-02 Auburn University Genetic engineering of plant chloroplasts
US5429939A (en) 1989-04-21 1995-07-04 Kirin Beer Kabushiki Kaisha DNA sequences useful for the synthesis of carotenoids
EP0462231A4 (en) 1989-08-01 1992-05-13 Pioneer Hi-Bred International, Inc. Transcriptional activators of anthocyanin biosynthesis as visual markers for plant transformation
GB8928179D0 (en) 1989-12-13 1990-02-14 Ici Plc Dna,constructs,cells and plants derived therefrom
US5618988A (en) 1990-03-02 1997-04-08 Amoco Corporation Enhanced carotenoid accumulation in storage organs of genetically engineered plants
US5545816A (en) 1990-03-02 1996-08-13 Amoco Corporation Phytoene biosynthesis in genetically engineered hosts
US5684238A (en) 1990-03-02 1997-11-04 Amoco Corporation Biosynthesis of zeaxanthin and glycosylated zeaxanthin in genetically engineered hosts
DE69132769T2 (en) 1990-03-02 2002-04-18 Bp Corp North America Inc BIOSYNTHESIS OF CAROTINOIDS IN GENETICALLY PRODUCED HOST CELLS
MY108071A (en) 1990-05-23 1996-08-15 Pentad Foods Int Stabilization and recovery method for tocotrienol and tocopherol products.
EP0531639B1 (en) 1991-07-18 1999-09-01 F. Hoffmann-La Roche Ag Tocopherol cyclase
GB9204583D0 (en) 1992-03-03 1992-04-15 Unilever Plc Recombinant plant enzyme
EP0668919B1 (en) 1992-11-17 2003-06-04 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
WO1994012014A1 (en) 1992-11-20 1994-06-09 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
CA2150133A1 (en) 1993-02-05 1994-08-18 Vincent Jean-Marie Armel Arondel Altered linolenic and linoleic acid content in plants
US6291745B1 (en) 1993-04-02 2001-09-18 Pioneer Hi-Bred International, Inc. Limonene and other downstream metabolites of geranyl pyrophosphate for insect control in plants
JPH08509871A (en) 1993-09-30 1996-10-22 アグラシータス インコーポレイテッド Transgenic cotton plants producing heterologous peroxidase
US5792903A (en) 1993-10-25 1998-08-11 Yissum Research Development Company Of Hebrew University Of Jerusalem Lycopene cyclase gene
JP3375639B2 (en) 1993-12-27 2003-02-10 麒麟麦酒株式会社 DNA chain useful for xanthophyll synthesis and method for producing xanthophyll
US5880332A (en) 1994-03-01 1999-03-09 Centre National De La Recherche Scientifique DNA constructs related to capsanthin capsorubin synthase, cells and plants derived therefrom
JP3198842B2 (en) 1994-03-24 2001-08-13 トヨタ自動車株式会社 Geranylgeranyl diphosphate synthase and DNA encoding the same
WO1996002650A2 (en) 1994-07-18 1996-02-01 Zeneca Limited Dna, constructs, cells and plants derived therefrom
EP0725137B2 (en) 1994-08-23 2005-03-02 Kirin Beer Kabushiki Kaisha Keto group introducing enzyme, dna coding for the same, and process for producing ketocarotenoid
DE4438232A1 (en) 1994-10-26 1996-05-02 Guenter Prof Dr Fuhr Cryopreservation and low-temperature processing of biological cells
DE19501906A1 (en) 1995-01-23 1996-07-25 Basf Ag Transketolase
AU5897796A (en) 1995-05-17 1996-11-29 Centre National De La Recherche Scientifique Dna sequences encoding a lycopene cyclase, antisense sequenc es derived therefrom and their use for the modification of c arotenoids levels in plants
FR2734842B1 (en) 1995-06-02 1998-02-27 Rhone Poulenc Agrochimie DNA SEQUENCE OF A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE AND OBTAINING PLANTS CONTAINING A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE, TOLERANT TO CERTAIN HERBICIDES
JP3538998B2 (en) 1995-09-01 2004-06-14 トヨタ自動車株式会社 Long-chain prenyl diphosphate synthase
US6015939A (en) 1995-11-07 2000-01-18 Calgene Llc Plant VDE genes and methods related thereto
US5916791A (en) 1995-11-24 1999-06-29 Hirschberg; Joseph Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a β--C--4--oxygenase activity for biotechnological production of (3S,3S)astaxanthin
US6087563A (en) 1996-01-29 2000-07-11 Arizona Board Of Regents On Behalf Of The University Of Arizona Cloned arabidopsis p-hydroxyphenyl pyruvic acid dioxygenase DNA
AU3644697A (en) 1996-06-27 1998-01-14 E.I. Du Pont De Nemours And Company Plant gene for (p)-hydroxyphenylpyruvate dioxygenase
CN1238008A (en) 1996-07-25 1999-12-08 美国氰胺公司 HPPD gene and inhibitors
WO1998006862A1 (en) 1996-08-09 1998-02-19 Calgene Llc Methods for producing carotenoid compounds and speciality oils in plant seeds
US6429356B1 (en) 1996-08-09 2002-08-06 Calgene Llc Methods for producing carotenoid compounds, and specialty oils in plant seeds
US5858367A (en) * 1997-03-27 1999-01-12 Case Western Reserve University Methods for screening for antimicrobials utilizing AarC and compositions thereof
DE19730066A1 (en) 1997-07-14 1999-01-21 Basf Ag DNA sequence coding for a hydroxyphenylpyruvate dioxygenase and its overproduction in plants
US6642434B1 (en) 1997-07-25 2003-11-04 University Of Community College System Of Nevada Transgenic plants with γ-tocopherol methyltransferase
ATE280832T1 (en) 1997-08-01 2004-11-15 Performance Plants Inc METHOD OF PRODUCING A DROUGHT RESISTANT PLANT
WO1999011757A1 (en) 1997-09-02 1999-03-11 Washington State University Research Foundation NUCLEIC AND AMINO ACID SEQUENCES FOR A NOVEL TRANSKETOLASE FROM $i (MENTHA PIPERITA)
US5876964A (en) 1997-10-16 1999-03-02 Washington State University Research Foundation Geranyl diphosphate synthase from mint
AU3749199A (en) 1998-04-24 1999-11-16 E.I. Du Pont De Nemours And Company Carotenoid biosynthesis enzymes
PL197407B1 (en) 1998-05-13 2008-03-31 Bayer Bioscience Gmbh Transgenic plants with a modified activity of a plastidial adp/atp translocator
FR2778527A1 (en) 1998-05-18 1999-11-19 Rhone Poulenc Agrochimie Producing tomato, cereal or oilseed plants, especially maize, oilseed rape, soya or sunflower plants, from which tocopherols can be extracted and purified
AU4863099A (en) 1998-07-06 2000-01-24 Dcv, Inc. Doing Business As Bio-Technical Resources Method of vitamin production
EP1571221B1 (en) 1998-08-04 2011-10-12 CropDesign N.V. Genes involved in tolerance to environmental stress
AU5572599A (en) 1998-08-21 2000-03-14 Regents Of The University Of Michigan, The Role of human kis (hkis) as an inhibitory kinase of the cyclin-dependent kinase inhibitor p27. compositions, methods and uses thereof to control cell proliferation
EP1107662A4 (en) 1998-08-25 2003-07-02 Univ Nevada Manipulation of tocopherol levels in transgenic plants
WO2000014207A2 (en) 1998-09-08 2000-03-16 E.I. Du Pont De Nemours And Company Plant farnesyltransferases
US6043072A (en) 1998-11-05 2000-03-28 Washington State University Research Foundation Nucleic acids encoding Taxus geranylgeranyl diphosphate synthase, and methods of use
EP1135453A1 (en) 1998-12-02 2001-09-26 Colgate-Palmolive Company High foaming, grease cutting light duty liquid detergent
WO2000032757A2 (en) 1998-12-03 2000-06-08 E.I. Du Pont De Nemours And Company Plant vitamin e biosynthetic enzymes
AU2163300A (en) 1998-12-04 2000-06-26 E.I. Du Pont De Nemours And Company Plant 1-deoxy-d-xylulose 5-phosphate reductoisomerase
EP1141344A2 (en) 1999-01-15 2001-10-10 Syngenta Participations AG Herbicide target gene and methods
US6281017B1 (en) 1999-02-03 2001-08-28 Washington State University Research Foundation 1-deoxy-d-xylulose-5-phosphate reductoisomerases and method of use
EP1033405A3 (en) 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
ATE446370T1 (en) 1999-04-12 2009-11-15 Monsanto Technology Llc OIL CONTAINING BRASSICASTANOL
JP2002541851A (en) 1999-04-15 2002-12-10 カルジーン エルエルシー Nucleic acid sequence of protein involved in isoprenoid synthesis
DE19918949A1 (en) 1999-04-27 2000-11-23 Basf Ag Overexpression of a DNA sequence coding for a 1-deoxy-D-xylulose-5-phosphate reductoisomerase in plants
WO2000068393A1 (en) 1999-05-07 2000-11-16 Pioneer Hi-Bred International, Inc. Phytyl/prenyltransferase nucleic acids, polypeptides and uses thereof
EP1063297B1 (en) 1999-06-22 2008-12-17 Korea Kumho Petrochemical Co. Ltd. Farnesyl pyrophosphate synthase (FPS) derived from seedlings of sunflower (Helianthus annus)
DE19931834A1 (en) 1999-07-09 2001-01-11 Sungene Gmbh & Co Kgaa Identification and overexpression of a DNA sequence coding for a 2-methyl-6-phytylhydroquinone methyltransferase in plants
US7365185B2 (en) * 2000-07-19 2008-04-29 Monsanto Technology Llc Genomic plant sequences and uses thereof
AU6826900A (en) 1999-07-30 2001-02-19 Bayer Aktiengesellschaft Method of determining the activity of 1-deoxy-d-xylulose-5-phosphate reductoisomerase and 1-deoxy-d-xylulose-5-phosphate synthase
DE19935967A1 (en) 1999-07-30 2001-02-01 Bayer Ag New DNA encoding Arabidopsis thaliana 1-deoxy-D-xylulose-5-phosphate reductoisomerase for identifying modulators of the enzyme that can be used as herbicides, antibiotic or anti-malarial agents
DE19937957A1 (en) 1999-08-11 2001-02-15 Sungene Gmbh & Co Kgaa Homogenate dioxygenase
US6645747B1 (en) 1999-09-21 2003-11-11 E. I. Du Pont De Nemours And Company Cis-prenyltransferases from plants
EP1244696A2 (en) 1999-12-16 2002-10-02 BASF Plant Science GmbH Moss genes from physcomitrella patens encoding proteins involved in the synthesis of tocopherols, carotenoids and aromatic amino acids
DE10009002A1 (en) 2000-02-25 2001-08-30 Sungene Gmbh & Co Kgaa A new homogentisatephytyltransferase protein encoded by the open reading frame slr1376 from Synechocystis species. PCC6803 is useful to provide transgenic plants producing vitamin E
WO2001079472A2 (en) 2000-04-14 2001-10-25 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
AR028450A1 (en) 2000-05-12 2003-05-07 Monsanto Technology Llc MCTODES TO PRODUCE CAROTENOID COMPOUNDS AND SPECIAL OILS IN PLANT SEEDS
AR030430A1 (en) 2000-06-29 2003-08-20 Sungene Gmbh & Co Kgaa PROCEDURE FOR THE OBTAINING OF FINE CHEMICALS BY CULTURE OF ORGANISMS THAT PRESENT A MODIFIED SHIQUIMATE ROUTE, NUCLEINIC ACID COMPOSITION, USE OF SUCH NUCLEINIC ACID FOR THE OBTAINING OF TRANSGENIC PLANTS, GENETICALLY PRODUCED PROCEDURE ORGANISM
AU2001290522B2 (en) 2000-08-07 2006-11-30 Monsanto Technology Llc Methyl-D-erythritol phosphate pathway genes
DE10046462A1 (en) 2000-09-19 2002-05-29 Sungene Gmbh & Co Kgaa Improved procedures for vitamin E biosynthesis
WO2002026933A2 (en) 2000-09-29 2002-04-04 Cargill Incorporated Isoprenoid production
AU2001296577A1 (en) 2000-10-05 2002-04-15 E.I. Du Pont De Nemours And Company Chlorophyllases
WO2002033060A2 (en) 2000-10-14 2002-04-25 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
FR2817557B1 (en) 2000-12-05 2005-05-06 Aventis Cropscience Sa NEW TARGETS FOR HERBICIDES AND TRANSGENIC PLANTS RESISTANT TO THESE HERBICIDES
WO2002063022A2 (en) 2001-02-08 2002-08-15 Monsanto Technology Llc Plant regulatory sequences
ES2318004T3 (en) 2001-05-09 2009-05-01 Monsanto Technology Llc TYRA GENES AND USES OF THE SAME.
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
WO2003016482A2 (en) 2001-08-17 2003-02-27 Monsanto Technology Llc Methyltransferase genes and uses thereof
DE60235252D1 (en) 2001-10-25 2010-03-18 Monsanto Technology Llc AROMATIC METHYLTRANSFERASES AND THEIR USE
BR0308740A (en) 2002-03-19 2007-01-09 Monsanto Technology Llc homogenous prenyl transferase ("hpt") nucleic acids and polypeptides, and their use
AU2003268083A1 (en) 2002-08-05 2004-02-23 Monsanto Technology, Llc Tocopherol biosynthesis related genes and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058649A1 (en) * 1998-05-13 1999-11-18 University Of Maryland Methods of modifying the production of isopentenyl pyrophosphate, dimethylallyl pyrophosphate and/or isoprenoids
DE19835219A1 (en) * 1998-08-05 2000-02-10 Basf Ag Use of 1-deoxy-D-xylulose-5-phosphate synthase DNA to produce plants with increased tocopherol, vitamin K, chlorophyll and/or carotenoid content
WO2000008169A1 (en) * 1998-08-05 2000-02-17 Sungene Gmbh & Co.Kgaa Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants
WO2000017233A2 (en) * 1998-09-22 2000-03-30 Jomaa Pharmaka Gmbh Genes of the 1-desoxy-d-xylulose biosynthetic pathway

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BAKER J ET AL: "SEQUENCE AND CHARACTERIZATION OF THE GCPE GENE OF ESCHERICHIA COLI", FEMS MICROBIOLOGY LETTERS, AMSTERDAM, NL, vol. 94, 1992, pages 175 - 180, XP002911676, ISSN: 0378-1097 *
DATABASE EMBL [online] 18 July 1997 (1997-07-18), SATO S. ET AL., XP002220622, retrieved from EBI Database accession no. AB005246; BAB09833.1 *
DATABASE EMBL [online] 2 July 1999 (1999-07-02), XP002221177, retrieved from EBI Database accession no. AQ690643 *
HECHT S ET AL: "Studies on the nonmevalonate pathway to terpenes: The role of the GcpE (IspG) protein", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 98, no. 26, 18 December 2001 (2001-12-18), pages 14837 - 14842, XP002192767, ISSN: 0027-8424 *
QUEROL J ET AL: "Functional analysis of the Arabidopsis thaliana GCPE protein involved in plastid isoprenoid biosynthesis", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 514, no. 2-3, 13 March 2002 (2002-03-13), pages 343 - 346, XP004347724, ISSN: 0014-5793 *
SATO S ET AL.: "STRUCTURAL ANALYSIS OF ARABIDOPSIS THALIANA CHROMOSOME 5. I. SEQUENCE FEATURES OF THE 1.6 MB REGIONS COVERED BY TWENTY PHYSICALLY ASSIGNED P1 CLONES", DNA RESEARCH, vol. 4, 1997, pages 215 - 230, XP000989704 *

Also Published As

Publication number Publication date
AU2001290522B2 (en) 2006-11-30
AU9052201A (en) 2002-02-18
EP1356033A2 (en) 2003-10-29
US20020069426A1 (en) 2002-06-06
US6841717B2 (en) 2005-01-11
EP1356033B1 (en) 2009-10-28
DE60140312D1 (en) 2009-12-10
US20080244790A1 (en) 2008-10-02
CA2418436C (en) 2017-07-11
ATE447017T1 (en) 2009-11-15
US7405343B2 (en) 2008-07-29
CA2418436A1 (en) 2002-02-14
AR030124A1 (en) 2003-08-13
US20050223435A1 (en) 2005-10-06
WO2002012478A8 (en) 2002-07-04
WO2002012478A2 (en) 2002-02-14

Similar Documents

Publication Publication Date Title
WO2002012478A3 (en) Methyl-d-erythritol phosphate pathway genes
WO2003016482A3 (en) Methyltransferase genes and uses thereof
WO2003020931A3 (en) Sirna knockout assay method and constructs
WO2003034812A3 (en) Aromatic methyltransferases and uses thereof
WO2002012501A3 (en) Anti-dual integrin antibodies, compositions, methods and uses
EP1994142A4 (en) Methods and compositions for the rapid isolation of small rna molecules
WO2006031800A3 (en) Reverse transfection of cell arrays
WO2004013312A3 (en) Tocopherol biosynthesis related genes and uses thereof
WO2007040592A8 (en) Making nucleic acid sequences in parallel and use
WO2002095055A8 (en) Compositions and methods for use in isolation of nucleic acid molecules
WO2001036641A3 (en) DOUBLE-STRANDED RNA RECEPTOR (dsRNA-R) AND METHODS RELATING THERETO
WO2002006457A3 (en) Novel lipase genes
WO2003025154A3 (en) Methods and compositions for the construction and use of fusion libraries
WO2001096373A3 (en) Fluorescent timer proteins and methods for their use
WO2002029018A3 (en) Divinyl ether synthase gene and protein, and uses thereof
WO2003040681A3 (en) Genes coding for metabolic pathway proteins
WO2003038041A3 (en) Il-4 mutein proteins, antibodies, compositions, methods and uses
WO2002022826A3 (en) Methods and compositions for the construction and use of fusion libraries
DE69928395D1 (en) CYCLIN-E2 PROTEINS AND ENCODING GENES
WO2004011637A3 (en) Modified adamts4 molecules and method of use thereof
WO2003057821A3 (en) Mut-il-18 or mut-il-18r proteins, antibodies, compositions, methods and uses
WO2001066752A3 (en) Reproduction-specific genes
WO2000047714A3 (en) Isolation and characterization of heat shock protein
WO2002028893A3 (en) Plant cyclin-dependent kinase inhibitors
WO2002090506A3 (en) Metabolite transporters

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: C1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

CFP Corrected version of a pamphlet front page
WWE Wipo information: entry into national phase

Ref document number: 2418436

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001290522

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2001970529

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 2001970529

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP