WO2002012344A3 - Methods for using 14266, a human g protein-coupled receptor - Google Patents

Methods for using 14266, a human g protein-coupled receptor Download PDF

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Publication number
WO2002012344A3
WO2002012344A3 PCT/US2001/024835 US0124835W WO0212344A3 WO 2002012344 A3 WO2002012344 A3 WO 2002012344A3 US 0124835 W US0124835 W US 0124835W WO 0212344 A3 WO0212344 A3 WO 0212344A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
protein
relates
polynucleotides
invention further
Prior art date
Application number
PCT/US2001/024835
Other languages
French (fr)
Other versions
WO2002012344A2 (en
Inventor
Nadine S Weich
Original Assignee
Millennium Pharm Inc
Nadine S Weich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Nadine S Weich filed Critical Millennium Pharm Inc
Priority to EP01957494A priority Critical patent/EP1311546A2/en
Priority to AU2001279232A priority patent/AU2001279232A1/en
Publication of WO2002012344A2 publication Critical patent/WO2002012344A2/en
Publication of WO2002012344A3 publication Critical patent/WO2002012344A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to methods for using a human G protein-coupled receptor (14266) belonging to the family of mammalian G protein-coupled receptors. The invention also relates to methods for using polynucleotides encoding the 14266 receptor. The invention relates to methods for detecting the presence of a 14266 polypeptide of a 14266 polynucleotide and kits comprising reagents for detecting the presence of a 14266 polypeptide or polynucleotide. The invention further relates to methods of modulating the level or activity of a 14266 polypeptide in a cell. The invention further relates to drug-screening methods using the 14266 polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the 14266 polypeptides and polynucleotides. The invention further relates to agonists and antagonists identified by drug screening methods with the 14266 polypeptides and polynucleotides as a target.
PCT/US2001/024835 2000-08-09 2001-08-08 Methods for using 14266, a human g protein-coupled receptor WO2002012344A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01957494A EP1311546A2 (en) 2000-08-09 2001-08-08 Methods for using 14266, a human g protein-coupled receptor
AU2001279232A AU2001279232A1 (en) 2000-08-09 2001-08-08 Methods for using 14266, a human g protein-coupled receptor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63439200A 2000-08-09 2000-08-09
US09/634,392 2000-08-09

Publications (2)

Publication Number Publication Date
WO2002012344A2 WO2002012344A2 (en) 2002-02-14
WO2002012344A3 true WO2002012344A3 (en) 2002-10-03

Family

ID=24543583

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/024835 WO2002012344A2 (en) 2000-08-09 2001-08-08 Methods for using 14266, a human g protein-coupled receptor

Country Status (3)

Country Link
EP (1) EP1311546A2 (en)
AU (1) AU2001279232A1 (en)
WO (1) WO2002012344A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006005461A2 (en) * 2004-07-15 2006-01-19 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 27 (gpr27)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046378A1 (en) * 1998-03-12 1999-09-16 Yamanouchi Pharmaceutical Co., Ltd. Novel g protein-coupled receptor proteins
WO2000028028A1 (en) * 1998-11-06 2000-05-18 Millennium Pharmaceuticals, Inc. G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
WO2001007482A1 (en) * 1999-07-27 2001-02-01 Smithkline Beecham Corporation Gpr27, a g-protein coupled receptor
WO2001032865A1 (en) * 1999-11-03 2001-05-10 Merck Patent Gmbh Human gpr27-like g-protein coupled receptor polypeptide and polynucleotide sequences

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046378A1 (en) * 1998-03-12 1999-09-16 Yamanouchi Pharmaceutical Co., Ltd. Novel g protein-coupled receptor proteins
EP1067183A1 (en) * 1998-03-12 2001-01-10 Yamanouchi Pharmaceutical Co. Ltd. Novel g protein-coupled receptor proteins
WO2000028028A1 (en) * 1998-11-06 2000-05-18 Millennium Pharmaceuticals, Inc. G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
WO2001007482A1 (en) * 1999-07-27 2001-02-01 Smithkline Beecham Corporation Gpr27, a g-protein coupled receptor
WO2001032865A1 (en) * 1999-11-03 2001-05-10 Merck Patent Gmbh Human gpr27-like g-protein coupled receptor polypeptide and polynucleotide sequences

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MATSUMOTO M ET AL: "An Evolutionarily Conserved G-Protein coupled Receptor Family, SREB, Expressed in the Central Nervous System", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 272, no. 2, 7 June 2000 (2000-06-07), pages 576 - 582, XP002164712, ISSN: 0006-291X *
O'DOWD B F ET AL: "DISCOVERY OF THREE NOVEL G-PROTEIN-COUPLED RECEPTOR GENES", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 47, no. 2, 15 January 1998 (1998-01-15), pages 310 - 313, XP000863786, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
AU2001279232A1 (en) 2002-02-18
WO2002012344A2 (en) 2002-02-14
EP1311546A2 (en) 2003-05-21

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