WO2002010198A3 - Polynucleotides and polypeptides - Google Patents

Polynucleotides and polypeptides Download PDF

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Publication number
WO2002010198A3
WO2002010198A3 PCT/GB2001/003390 GB0103390W WO0210198A3 WO 2002010198 A3 WO2002010198 A3 WO 2002010198A3 GB 0103390 W GB0103390 W GB 0103390W WO 0210198 A3 WO0210198 A3 WO 0210198A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotides
polypeptides
relates
sequences
mediated
Prior art date
Application number
PCT/GB2001/003390
Other languages
French (fr)
Other versions
WO2002010198A2 (en
Inventor
Ian Mcdonald Hayes
Raymond Anthony Jupp
William Kenneth Pollack
Original Assignee
Aventis Pharma Ltd
Ian Mcdonald Hayes
Raymond Anthony Jupp
William Kenneth Pollack
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0018700A external-priority patent/GB0018700D0/en
Application filed by Aventis Pharma Ltd, Ian Mcdonald Hayes, Raymond Anthony Jupp, William Kenneth Pollack filed Critical Aventis Pharma Ltd
Priority to AU2002227496A priority Critical patent/AU2002227496A8/en
Priority to AU2002227496A priority patent/AU2002227496A1/en
Publication of WO2002010198A2 publication Critical patent/WO2002010198A2/en
Publication of WO2002010198A3 publication Critical patent/WO2002010198A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to polynucleotide and polypeptide sequences which are associated with eosinophil mediated inflammatory diseases, such as asthma. The invention also relates to means and methods for modulating the expression and/or activity of these sequences, preferably in the treatment or prevention of inflammatory disease mediated by eosinophils. Screening assays for agents which act as agonists or antagonists of these polynucleotides or polypeptides are also provided.
PCT/GB2001/003390 2000-07-31 2001-07-30 Polynucleotides and polypeptides WO2002010198A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002227496A AU2002227496A8 (en) 2000-07-31 2001-07-30 Polynucleotides and polypeptides
AU2002227496A AU2002227496A1 (en) 2000-07-31 2001-07-30 Polynucleotides and polypeptides

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0018700.5 2000-07-31
GB0018700A GB0018700D0 (en) 2000-07-31 2000-07-31 Polynucleotides and polypeptides
GB0031021.9 2000-12-19
GB0031021A GB0031021D0 (en) 2000-07-31 2000-12-19 Polynucleotides and polypeptides

Publications (2)

Publication Number Publication Date
WO2002010198A2 WO2002010198A2 (en) 2002-02-07
WO2002010198A3 true WO2002010198A3 (en) 2007-10-18

Family

ID=26244763

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/003390 WO2002010198A2 (en) 2000-07-31 2001-07-30 Polynucleotides and polypeptides

Country Status (3)

Country Link
AU (2) AU2002227496A8 (en)
GB (1) GB0031021D0 (en)
WO (1) WO2002010198A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7217799B2 (en) 2000-08-28 2007-05-15 Agensys, Inc. Antibodies that recognize the 85P1B3 protein useful in treatment and detection of cancer
WO2021248053A2 (en) * 2020-06-04 2021-12-09 Godx, Inc. Point-of-care sars-cov-2 virus diagnostic device and methods of use thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRENNER V ET AL: "Analysis of cellular adhesion by microarray expression profiling", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 250, no. 1-2, 1 April 2001 (2001-04-01), pages 15 - 28, XP004230692, ISSN: 0022-1759 *
DATABASE EMBL [online] 14 March 2000 (2000-03-14), BIRREN B. ET AL., XP002190683, retrieved from EBI Database accession no. AC025342 *
KILTY I C ET AL: "Studies of differential gene expression in clinically derived eosinophil populations.", CLINICAL AND EXPERIMENTAL ALLERGY, vol. 29, no. 12, December 1999 (1999-12-01), pages 1671 - 1680, XP001038352, ISSN: 0954-7894 *
TEMPLE R ET AL.: "Microarray analysis of eosinophils reveals a number of candidate survival and apoptosis genes.", AM J RESPIR CELL MOL BIOL, vol. 25, no. 4, October 2001 (2001-10-01), pages 425 - 433, XP001037077 *

Also Published As

Publication number Publication date
AU2002227496A1 (en) 2002-02-13
WO2002010198A2 (en) 2002-02-07
AU2002227496A8 (en) 2007-12-20
GB0031021D0 (en) 2001-01-31

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