WO2002007675A3 - Omega-conopeptides - Google Patents

Omega-conopeptides Download PDF

Info

Publication number
WO2002007675A3
WO2002007675A3 PCT/US2001/023041 US0123041W WO0207675A3 WO 2002007675 A3 WO2002007675 A3 WO 2002007675A3 US 0123041 W US0123041 W US 0123041W WO 0207675 A3 WO0207675 A3 WO 0207675A3
Authority
WO
WIPO (PCT)
Prior art keywords
conopeptides
agents
propeptides
omega
encoding
Prior art date
Application number
PCT/US2001/023041
Other languages
French (fr)
Other versions
WO2002007675A2 (en
Inventor
Baldomero M Olivera
J Michael Mcintosh
Maren Watkins
James E Garrett
Ki-Joon Shon
Richard Jacobsen
Robert M Jones
G Edward Cartier
Original Assignee
Univ Utah Res Found
Cognetix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utah Res Found, Cognetix Inc filed Critical Univ Utah Res Found
Priority to JP2002513413A priority Critical patent/JP2004512025A/en
Priority to CA002416287A priority patent/CA2416287A1/en
Priority to EP01957214A priority patent/EP1311283A4/en
Priority to AU2001278982A priority patent/AU2001278982A1/en
Publication of WO2002007675A2 publication Critical patent/WO2002007675A2/en
Publication of WO2002007675A3 publication Critical patent/WO2002007675A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention relates to φ-conopeptides, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents, as cardiovascular agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.
PCT/US2001/023041 2000-07-21 2001-07-23 Omega-conopeptides WO2002007675A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002513413A JP2004512025A (en) 2000-07-21 2001-07-23 Omega-conopeptide
CA002416287A CA2416287A1 (en) 2000-07-21 2001-07-23 Omega-conopeptides
EP01957214A EP1311283A4 (en) 2000-07-21 2001-07-23 Omega-conopeptides
AU2001278982A AU2001278982A1 (en) 2000-07-21 2001-07-23 Omega-conopeptides

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21961600P 2000-07-21 2000-07-21
US60/219,616 2000-07-21
US26588801P 2001-02-05 2001-02-05
US60/265,888 2001-02-05

Publications (2)

Publication Number Publication Date
WO2002007675A2 WO2002007675A2 (en) 2002-01-31
WO2002007675A3 true WO2002007675A3 (en) 2003-03-06

Family

ID=26914073

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/023041 WO2002007675A2 (en) 2000-07-21 2001-07-23 Omega-conopeptides

Country Status (5)

Country Link
EP (1) EP1311283A4 (en)
JP (1) JP2004512025A (en)
AU (1) AU2001278982A1 (en)
CA (1) CA2416287A1 (en)
WO (1) WO2002007675A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8673856B2 (en) 2006-11-04 2014-03-18 Anygen Co., Ltd. Omega conotoxins
WO2011032233A1 (en) * 2009-09-21 2011-03-24 The University Of Queensland Novel omega conotoxin peptides
JP6977979B2 (en) * 2015-06-09 2021-12-08 国立大学法人大阪大学 Nerve injury treatment or preventive medicine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587454A (en) * 1991-12-30 1996-12-24 Neurex Corporation Omega conopeptide compositions
US5591821A (en) * 1993-07-16 1997-01-07 The University Of Utah Omega-conotoxin peptides
WO1999054350A1 (en) * 1998-04-16 1999-10-28 The University Of Queensland Novel omega conotoxin peptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231011A (en) * 1991-04-18 1993-07-27 University Of Utah Segregated folding determinants for small disulfide-rich peptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587454A (en) * 1991-12-30 1996-12-24 Neurex Corporation Omega conopeptide compositions
US5591821A (en) * 1993-07-16 1997-01-07 The University Of Utah Omega-conotoxin peptides
WO1999054350A1 (en) * 1998-04-16 1999-10-28 The University Of Queensland Novel omega conotoxin peptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1311283A4 *

Also Published As

Publication number Publication date
CA2416287A1 (en) 2002-01-31
WO2002007675A2 (en) 2002-01-31
EP1311283A4 (en) 2004-09-01
JP2004512025A (en) 2004-04-22
EP1311283A2 (en) 2003-05-21
AU2001278982A1 (en) 2002-02-05

Similar Documents

Publication Publication Date Title
WO2002072005A3 (en) Linear y-carboxyglutamate rich conotoxins
IL157478A0 (en) Method for the synthesis of 2', 3'-didehydronucleosides
WO2001066564A3 (en) Gamma-secretase inhibitors
MXPA03001001A (en) Anticonvulsant derivatives useful for the treatment of depression.
AU2002224927A1 (en) Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds
IL166710A0 (en) Process for the preparation of 4-ÄÄ4-ÄÄ-(2-cyanoethenyl)2,6-dimethylphenylÜaminoÜ-2-pyrimidinylÜaminoÜbenzonitrile
WO2001060347A3 (en) Method for treating ocular pain
MXPA03009527A (en) Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds.
MXPA03010020A (en) Process for the preparation of urea.
HUP0303034A3 (en) Novel 7-azaindole-derivatives, use thereof as phosphodiesterase 4 inhibitors and method for producing the same
AU3657100A (en) Use of water-soluble beta-(1,3) glucans as agents for producing therapeutic skintreatment agents
WO2002030870A3 (en) Substituted c-cyclohexylmethylamine derivatives
WO2002007678A3 (en) Mu-conopeptides
WO2003037863A3 (en) Substituted indoles, method for production and use thereof for the inhibition of pain
IL157709A0 (en) Process for the preparation of 1,2-benzisoxazole-3-acetic acid
WO2002007675A3 (en) Omega-conopeptides
HUP0401577A3 (en) Process for the preparation of 2,4-didezoxyhexoses and 2,4,6-tridezoxyhexoses
MXPA03002926A (en) Process for the synthesis of 2,2,6,6-tetramethyl-4-oxopiperidine.
IL144066A0 (en) Process for the preparation of 1,1-cyclohexane diacetic monoamide
ZA200210361B (en) Method of administering bishosphonates.
SI1468686T1 (en) S-methyl-dihydro-ziprasidone for treatment of psychiatric disorders
HK1049485A1 (en) DithiepinoÄ6,5-BÜpyridines, and related compositions, methods of producing and uses.
ZA200110172B (en) Method of producing novolak resin.
AU5482001A (en) Method for producing caprolactam on the basis of 6-aminocapronitrile and subsequent purification by crystallization
IL137364A (en) Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 2416287

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001957214

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2001278982

Country of ref document: AU

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWP Wipo information: published in national office

Ref document number: 2001957214

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2003131327

Country of ref document: RU

Kind code of ref document: A

Format of ref document f/p: F

WWW Wipo information: withdrawn in national office

Ref document number: 2001957214

Country of ref document: EP