WO2001097871A3 - Collagen hemostatic pellets - Google Patents

Collagen hemostatic pellets Download PDF

Info

Publication number
WO2001097871A3
WO2001097871A3 PCT/EP2001/006794 EP0106794W WO0197871A3 WO 2001097871 A3 WO2001097871 A3 WO 2001097871A3 EP 0106794 W EP0106794 W EP 0106794W WO 0197871 A3 WO0197871 A3 WO 0197871A3
Authority
WO
WIPO (PCT)
Prior art keywords
collagen
pellets
hemostatic
gel
collagen hemostatic
Prior art date
Application number
PCT/EP2001/006794
Other languages
French (fr)
Other versions
WO2001097871A2 (en
Inventor
Wolfgang Biering
Original Assignee
Wolfgang Biering
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wolfgang Biering filed Critical Wolfgang Biering
Priority to AU2001279662A priority Critical patent/AU2001279662A1/en
Publication of WO2001097871A2 publication Critical patent/WO2001097871A2/en
Publication of WO2001097871A3 publication Critical patent/WO2001097871A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/102—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Subject of the invention are collagen hemostatic pellets containing collagen gel in the contacting surface. The hemostatic pellets preferably contain physiologically active substances as additives. They either are based on a homogeneous collagen composition, or comprise collagen gel as a layer. The further subject of the invention is the method of producing the collagen hemostatic pellets by dissolving a collagen source at an acid pH, optionally neutralizing the collagen solution to produce a gel at pH 6-8, and pelleting the gel by centrifugation, spray-drying, fluid-bed drying and/or encapsulating. The collagen hemostatic pellets according to the invention can be used in various surgical interventions, in particular for laparoscopic procedures.
PCT/EP2001/006794 2000-06-20 2001-06-15 Collagen hemostatic pellets WO2001097871A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001279662A AU2001279662A1 (en) 2000-06-20 2001-06-15 Collagen hemostatic pellets

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT10692000A AT411326B (en) 2000-06-20 2000-06-20 HEMOSTATIC COLLAGEN PELLETS
ATA1069/00 2000-06-20

Publications (2)

Publication Number Publication Date
WO2001097871A2 WO2001097871A2 (en) 2001-12-27
WO2001097871A3 true WO2001097871A3 (en) 2002-03-07

Family

ID=3684965

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/006794 WO2001097871A2 (en) 2000-06-20 2001-06-15 Collagen hemostatic pellets

Country Status (3)

Country Link
AT (1) AT411326B (en)
AU (1) AU2001279662A1 (en)
WO (1) WO2001097871A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6568398B2 (en) * 2001-03-07 2003-05-27 Edgar C. Cohen Method for hemostasis
US7074425B2 (en) 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
AU2011260274B2 (en) 2010-06-01 2015-07-02 Baxter Healthcare S.A. Process for making dry and stable hemostatic compositions
MX345479B (en) 2010-06-01 2017-02-01 Baxter Int Inc * Process for making dry and stable hemostatic compositions.
AU2011260258B2 (en) 2010-06-01 2015-07-09 Baxter Healthcare S.A. Process for making dry and stable hemostatic compositions
AU2012247480B2 (en) 2011-04-27 2016-09-22 Dilon Technologies Inc. Hemostatic compositions
EP3011974B1 (en) 2011-06-02 2018-08-08 University Of Louisville Research Foundation, Inc. Anti-nucleolin agent-conjugated nanoparticles
CA2865349C (en) 2012-03-06 2021-07-06 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
EP2825216B1 (en) 2012-06-12 2015-08-19 Ferrosan Medical Devices A/S Dry haemostatic composition
CN105358071B (en) 2013-06-21 2018-07-31 弗罗桑医疗设备公司 The dry composition of vacuum expansion and syringe for retaining the dry composition
CN105828844B (en) 2013-12-11 2019-09-27 弗罗桑医疗设备公司 Dry composition comprising squeezing out reinforcing agent
CN106999621B (en) 2014-10-13 2020-07-03 弗罗桑医疗设备公司 Dry composition for hemostasis and wound healing
AU2015371184B2 (en) 2014-12-24 2020-06-25 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
BR112017027695A2 (en) 2015-07-03 2018-09-04 Ferrosan Medical Devices As first and second substance retention and mixing syringe
AU2017310470B2 (en) 2016-08-12 2021-12-16 Dilon Technologies Inc. Hemostatic flowable
ES2968412T3 (en) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Method for preparing a hemostatic composition

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4393041A (en) * 1980-04-25 1983-07-12 International Minerals & Chemical Corp. Fibrin binder/carrier for active biochemical agents
US4581030A (en) * 1982-09-30 1986-04-08 Massachusetts General Hospital Collagen replacement prothesis for the cornea
US4711783A (en) * 1982-04-01 1987-12-08 Bioetica, S.A. Forms of microencapsulation of medicinal substances by homogeneous layers of native collagen
WO1996027662A1 (en) * 1995-03-03 1996-09-12 Metabolex, Inc. Novel encapsulation process by a gelling polymer
WO1998031403A1 (en) * 1997-01-16 1998-07-23 Cohesion Corporation Lyophilized collagen-based biomaterials, process of preparation and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505855A (en) * 1982-09-30 1985-03-19 Massachusetts General Hospital Transparent non-fibrilized collagen material by ultracentrifugation
IT1214505B (en) * 1987-03-12 1990-01-18 Gentili Ist Spa PROCEDURE FOR THE PREPARATION OF COLLAGEN AND PRODUCTS SO OBTAINED.
CA2251475C (en) * 1996-04-04 2006-09-05 Immuno Aktiengesellschaft Hemostatic sponge based on collagen
FR2777284B1 (en) * 1998-04-10 2000-05-26 Hamza Mansour PROCESS FOR THE STERILIZATION OF A NATIVE COLLAGEN IN A LIQUID MEDIUM, A STERILE NATIVE COLLAGEN OBTAINED, COMPOSITIONS CONTAINING THE SAME AND APPLICATIONS

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4393041A (en) * 1980-04-25 1983-07-12 International Minerals & Chemical Corp. Fibrin binder/carrier for active biochemical agents
US4711783A (en) * 1982-04-01 1987-12-08 Bioetica, S.A. Forms of microencapsulation of medicinal substances by homogeneous layers of native collagen
US4581030A (en) * 1982-09-30 1986-04-08 Massachusetts General Hospital Collagen replacement prothesis for the cornea
WO1996027662A1 (en) * 1995-03-03 1996-09-12 Metabolex, Inc. Novel encapsulation process by a gelling polymer
WO1998031403A1 (en) * 1997-01-16 1998-07-23 Cohesion Corporation Lyophilized collagen-based biomaterials, process of preparation and uses thereof

Also Published As

Publication number Publication date
ATA10692000A (en) 2003-05-15
AU2001279662A1 (en) 2002-01-02
AT411326B (en) 2003-12-29
WO2001097871A2 (en) 2001-12-27

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