WO2001094529A3 - Nouveau polypeptide, serine hydrolase humaine atp-dependante 21, et polynucleotide codant pour ce polypeptide - Google Patents

Nouveau polypeptide, serine hydrolase humaine atp-dependante 21, et polynucleotide codant pour ce polypeptide Download PDF

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Publication number
WO2001094529A3
WO2001094529A3 PCT/CN2001/000658 CN0100658W WO0194529A3 WO 2001094529 A3 WO2001094529 A3 WO 2001094529A3 CN 0100658 W CN0100658 W CN 0100658W WO 0194529 A3 WO0194529 A3 WO 0194529A3
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WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
serine proteinase
human atp
discloses
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PCT/CN2001/000658
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English (en)
Chinese (zh)
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WO2001094529A2 (fr
Inventor
Yumin Mao
Yi Xie
Original Assignee
Shanghai Biowindow Gene Dev
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Shanghai Biowindow Gene Dev, Yumin Mao, Yi Xie filed Critical Shanghai Biowindow Gene Dev
Priority to AU85648/01A priority Critical patent/AU8564801A/en
Publication of WO2001094529A2 publication Critical patent/WO2001094529A2/fr
Publication of WO2001094529A3 publication Critical patent/WO2001094529A3/fr

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un nouveau polypeptide, une sérine hydrolase humaine ATP-dépendante 21, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la sérine hydrolase humaine ATP-dépendante 21.
PCT/CN2001/000658 2000-04-29 2001-04-28 Nouveau polypeptide, serine hydrolase humaine atp-dependante 21, et polynucleotide codant pour ce polypeptide WO2001094529A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU85648/01A AU8564801A (en) 2000-04-29 2001-04-28 A novel polypeptide, a human atp dependant serine proteinase 21 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN00115512A CN1321768A (zh) 2000-04-29 2000-04-29 一种新的多肽——人atp依赖的丝氨酸蛋白水解酶21和编码这种多肽的多核苷酸

Publications (2)

Publication Number Publication Date
WO2001094529A2 WO2001094529A2 (fr) 2001-12-13
WO2001094529A3 true WO2001094529A3 (fr) 2002-05-02

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000658 WO2001094529A2 (fr) 2000-04-29 2001-04-28 Nouveau polypeptide, serine hydrolase humaine atp-dependante 21, et polynucleotide codant pour ce polypeptide

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Country Link
CN (1) CN1321768A (fr)
AU (1) AU8564801A (fr)
WO (1) WO2001094529A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7103563B1 (en) 2000-03-21 2006-09-05 America Online, Inc. System and method for advertising with an internet voice portal
CA2516455C (fr) 2003-02-20 2012-05-01 Seattle Genetics, Inc. Conjugues de medicaments anticorps anti-cd70, utilisation desdits conjugues dans le traitement du cancer et des troubles immunitaires

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063073A1 (fr) * 1998-05-21 1999-12-09 The Trustees Of Columbia University In The City Of New York Pak4 un nouveau gene codant pour une serine/threonine kinase
US6013464A (en) * 1995-01-06 2000-01-11 Onyx Pharmaceuticals, Inc. Human PAK65

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013464A (en) * 1995-01-06 2000-01-11 Onyx Pharmaceuticals, Inc. Human PAK65
WO1999063073A1 (fr) * 1998-05-21 1999-12-09 The Trustees Of Columbia University In The City Of New York Pak4 un nouveau gene codant pour une serine/threonine kinase

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MORI, E. ET AL.: "Cloning, nucleotide sequencing and expression of the azospirillum brasilense ion gene: involvement in iron uptake", J. BACTERIOL., vol. 178, no. 12, 1996, pages 3440 - 3446 *
STEPHENS, R.S. ET AL.: "Genome sequence of an obligate intracellular pathogen of humans: chlamydia trachomatis", SCIENCE, vol. 282, no. 5389, 1998, pages 754 - 759 *
SULSTON, J.E. AND WATERSTON, R.: "Toward a complete human genome sequence", GENOME RES., vol. 8, no. 11, 1998, pages 1097 - 1108 *

Also Published As

Publication number Publication date
WO2001094529A2 (fr) 2001-12-13
AU8564801A (en) 2001-12-17
CN1321768A (zh) 2001-11-14

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